Hotels Near
Mission District

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Featured Mission District Hotels

Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (2,993 reviews)
Great size rooms, dated but comfortable. Location is convenient but not my favourite area in San Francisco, however the transport get you everywhere in fast! Staff were super helpful

Reviewed on Apr 17, 2026

Handlery Union Square Hotel
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,569 reviews)
Staff was good. Facility needs refurbishing. Rooms are cramped and outdated.

Reviewed on Apr 16, 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,641 reviews)
Good location. Friendly staff.

Reviewed on Apr 16, 2026

Hilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,066 reviews)
Good location for walking around town and good rooms. Staff were also good.

Reviewed on Apr 16, 2026

Club Quarters Hotel in San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,390 reviews)
Excellent location and Helpful staff.

Reviewed on Apr 17, 2026

Hotel Riu Plaza Fisherman's Wharf
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,007 reviews)
I will be avoiding this hotel in the future. They overcharged my credit card and it took me over 3 weeks, 5 escalations and follow-ups to get my refund.

Reviewed on Apr 16, 2026

YOTEL San Francisco
Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel

3 out of 5
380 S Airport Boulevard South San Francisco CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,762 reviews)
I come just for the Breakfast & wonderful Staff..

Reviewed on Apr 17, 2026

Best Western Plus Grosvenor Airport Hotel
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

3.5 out of 5
68 Monarch Bay Dr San Leandro CA
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in San Leandro. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,394 reviews)
Was surprised by the $18 a night parking fee. Otherwise the room was clean and had a nice view of the bay

Reviewed on Apr 17, 2026

The Marina Inn on San Francisco Bay
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
501 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant ...
9.2/10 Wonderful! (1,237 reviews)
Great breakfast

Reviewed on Apr 17, 2026

The Marker Union Square San Francisco
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St San Francisco CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and Netflix. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,473 reviews)
Super nice and amenities downstairs are nice. Can use water to refill bottles. Very quiet and nice area. Elevator is small but only complaint

Reviewed on Apr 17, 2026

FOUND Hotel Carlton, Nob Hill
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,830 reviews)
Very clean, convenient to airport. Great views of the bay.

Reviewed on Apr 17, 2026

Bay Landing San Francisco Airport Hotel
Hotel Julian

Hotel Julian

3 out of 5
940 Sutter Street San Francisco CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Francisco. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Pier 39 and Oracle Park are located ...
8.6/10 Excellent! (731 reviews)
Finding parking initially was difficult but eventually I snagged a spot on the street 2 blocks away. Once checking in the receptionist did give me directions to their suggested parking garage that was around the block. I just came solo for a night. The room was modern with good lighting and a nice ...

Reviewed on Apr 16, 2026

Hotel Julian
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mission District

San Francisco is a city that has a lot going on, but you have your sights set on Mission District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mission District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mission District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Francisco so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mission District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mission District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mission District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mission District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $111
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mission District hotel you want, book it, and never look back. Because your great escape is ahead of you.