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Hotels in San Mateo

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Choose from 5190 San Mateo Hotel Deals

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,416 reviews)
Very nice

Reviewed on Apr 26, 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (5,635 reviews)
Amazing food, amazing amenities, very clean hotel and just a great location and experience. We are so picky and we will not stay anywhere else next time we come! Worth it!

Reviewed on Apr 26, 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,687 reviews)
Room was nice and always clean! Staff at front desk was kind and fast. I really wish you would offer room service! This was not hotels fault but our stay unfortunately got impacted with the neighbors having an intense domestic dispute. Security handled it but frustrating when you want relax and have ...

Reviewed on Apr 26, 2026

Hilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,068 reviews)
Good

Reviewed on Apr 26, 2026

Club Quarters Hotel in San Francisco
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,049 reviews)
Very clean . Great staff

Reviewed on Apr 26, 2026

Handlery Union Square Hotel
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,007 reviews)
The breakfast was good, easy

Reviewed on Apr 25, 2026

YOTEL San Francisco
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
  • 14 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,852 reviews)
Everything was good. No bad issues at all. Larger trash cans in the rooms would be the only change I would make.

Reviewed on Apr 25, 2026

Bay Landing San Francisco Airport Hotel
The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay

3.5 out of 5
68 Monarch Bay Dr San Leandro CA
  • 31 min drive from San Mateo County Event Center
Book a stay at this golf hotel in San Leandro. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,414 reviews)
Perfect

Reviewed on Apr 26, 2026

The Marina Inn on San Francisco Bay
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this luxury hotel in San Francisco. Enjoy a full-service spa, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,520 reviews)
This hotel is dated and not worth the price that they charge. Had to have them fix the toilet twice and have them fix the sink because it wasn’t draining. The sink shouldn’t have drainage issues at this price and management should check these things. Wallpaper peeling. I get that it’s a historic ...

Reviewed on Apr 23, 2026

Fairmont San Francisco
The Pickwick Hotel

The Pickwick Hotel

3.5 out of 5
85 5th St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
7.8/10 Good! (1,226 reviews)
Rooms were clean, hotel is a little outdated but other than that good stay.

Reviewed on Apr 26, 2026

The Pickwick Hotel
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.4/10 Very Good! (1,269 reviews)
The bedsheets are stained, and the floor wasn’t cleaned thoroughly.

Reviewed on Apr 25, 2026

Hilton San Francisco Union Square
Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

2 out of 5
326 S Airport Blvd South San Francisco CA
  • 24 min drive from San Mateo County Event Center
Book a stay at this business-friendly motel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the clean ...
6/10 (3,534 reviews)
We slept in our clothes. The hotel is in very bad shape. The shape. The bathroom pocket door did not close. Only hot water came out of the faust. The curtains were ripped. The door to the outdoors was dirty. The front desk would not call us a taxis to

Reviewed on Apr 26, 2026

Travelodge by Wyndham San Francisco Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Mateo.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 5,190 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Mateo for as low as $72.

How many hotels are there in San Mateo?

With over 5,190 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.