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Hotels in San Mateo

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Choose from 5171 San Mateo Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this family-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (3,003 reviews)
Beautiful grounds and lovely room.

Reviewed on Apr 12, 2026

Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,393 reviews)
Great staff

Reviewed on Apr 12, 2026

Hotel Riu Plaza Fisherman's Wharf
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,050 reviews)
Queen Bed was comfy and pillows were really nice. Very clean room. Only negative was the size of the room.

Reviewed on Apr 12, 2026

Club Quarters Hotel in San Francisco
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
  • 43 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,011 reviews)
Decent coffee and baked goods at breakfast. For some reason, my room wasn't cleaned unless I asked specifically.

Reviewed on Apr 11, 2026

YOTEL San Francisco
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
501 Geary St San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this boutique hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the restaurant ...
9.2/10 Wonderful! (1,226 reviews)
Great room and low street noise since our room was not face street, with comp water in the room. Free coffee & tea in the restaurant, though since small staff priority is understandably to the paid clients, after 15 minutes to wait to refill cafinated coffee, we end up leaving and going ...

Reviewed on Apr 11, 2026

The Marker Union Square San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
  • 44 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.4/10 Very Good! (1,248 reviews)
The sunset and view were amazing from the bar on the 46th floor

Reviewed on Apr 12, 2026

Hilton San Francisco Union Square
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and Netflix. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,461 reviews)
Good central position. Clean room and amenities. Staff welcoming and helpful.

Reviewed on Apr 12, 2026

FOUND Hotel Carlton, Nob Hill
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
  • 45 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,624 reviews)
clean room

Reviewed on Apr 11, 2026

Hilton San Francisco Financial District
Hotel Julian

Hotel Julian

3 out of 5
940 Sutter Street San Francisco CA
  • 45 min drive from San Mateo County Event Center
Stay at this hotel in San Francisco. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Pier 39 and Oracle Park are located ...
8.6/10 Excellent! (721 reviews)
Angie was super nice and helpful !

Reviewed on Apr 9, 2026

Hotel Julian
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
  • 47 min drive from San Mateo County Event Center
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (2,519 reviews)
Great social atmosphere downstairs in the common areas, great overall location.

Reviewed on Apr 11, 2026

Hotel Zephyr San Francisco
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
1550 Bayshore Hwy Burlingame CA
  • 14 min drive from San Mateo County Event Center
Book a stay at this business-friendly hotel in Burlingame. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (4,824 reviews)
Clean room and nice breakfast.

Reviewed on Apr 12, 2026

Bay Landing San Francisco Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Mateo

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Mateo.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Mateo’s 5,171 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $103. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Mateo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Mateo. No matter your reason for visiting San Mateo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Mateo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Mateo for as low as $103.

How many hotels are there in San Mateo?

With over 5,171 hotels in San Mateo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $103.

How to find cheap car rentals in San Mateo?

Finding a cheap car rental deal in San Mateo is as easy as scoring cheap hotels in San Mateo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.