Hotels Near
Clayton

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Featured Clayton Hotels

Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,181 reviews)
"Enjoyed our stay. Room was great and staff were friendly and helpful."

Reviewed on May 4, 2024

Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,875 reviews)
"I always stay here where I’m in St. Louis"

Reviewed on May 5, 2024

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
4 out of 5
7730 Bonhomme Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Popular attractions St. Louis ...
8.8/10 Excellent! (460 reviews)
"The pool wasn’t open! The baseboard was quite dirty in bathroom of 1109…staff was phenomenal!"

Reviewed on Apr 30, 2024

Le Méridien St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3 out of 5
216 N Meramec Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (719 reviews)
Nice but showing a little wear and tear
"Still a comfortable and relatively affordable place to stay in Clayton (although note it’s not really in the Galleria area as billed.) But it’s showing a little wear compared with my earlier visits when it was brand new. The light and alert sound on the legendary waffle maker was broken as was my ..."

Reviewed on Apr 30, 2024

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Homewood Suites by Hilton St Louis - Galleria
Homewood Suites by Hilton St Louis - Galleria
3 out of 5
8040 Clayton Road, Richmond Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,001 reviews)
"It was right next to the highway, so it was a little noisy, but not terrible. The room was spacious and clean, we enjoyed out time. The breakfast was great!! Our only downside was that there was a family that stayed at the same time and their kid kept pooping in the pool and hot tub so they had to ..."

Reviewed on Apr 29, 2024

Homewood Suites by Hilton St Louis - Galleria
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundable
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (2,999 reviews)
"Comfortable beds."

Reviewed on May 6, 2024

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,183 reviews)
In St. Louis for the Battlehawks game.
"Our room we booked had a slight chemical odor(I think from cleaning products). We called down to the front desk and Jack took care of us promptly! We were moved to another room right away and was very pleased with our new room. Jack was very professional and very accommodating. Jack made our stay ..."

Reviewed on May 5, 2024

Drury Plaza Hotel St. Louis at the Arch
The Last Hotel
The Last Hotel
4.5 out of 5
1501 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the bar in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"This was my second time staying here and it was just as good as the first time. It was clean and was a cute hotel."

Reviewed on May 5, 2024

The Last Hotel
Hilton St. Louis at the Ballpark
Hilton St. Louis at the Ballpark
4 out of 5
1 S Broadway, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff and ...
7.4/10 Good! (1,010 reviews)
"The stay was pretty nice. The room was pretty nice but it was a bit warm and the thermostat was programmed and couldn’t be changed manually. The elevator in the west bldg was hot and the hallways were too hot. The parking was overly expensive. I believe when you’re paying for the hotel the parking ..."

Reviewed on May 5, 2024

Hilton St. Louis at the Ballpark
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
2.5 out of 5
1200 S Kirkwood Road, Kirkwood, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,009 reviews)
"Rooms were clean and the included breakfast was good."

Reviewed on May 2, 2024

Best Western St. Louis-Kirkwood Route 66
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions St. Louis Union Station and Busch ...
9/10 Wonderful! (392 reviews)
"Absolutely beautiful hotel and so unique. My only complaint is the elevators are small and extremely slow. Nonetheless I will definitely recommend to others."

Reviewed on May 5, 2024

21C Museum Hotel St Louis
Angad Arts Hotel
Angad Arts Hotel
4 out of 5
3550 Samuel Shepard Drive, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the restaurant ...
8.8/10 Excellent! (1,022 reviews)
Clean and Neat Hotel but not enough information.
"This hotel was very neat. I was going to see a show at the Fox and the hotel is almost right across the street from the theatre so it was great for that purpose. There are some things I wish I had known prior to staying so I will share those here. Parking is in the back of the building for the hotel ..."

Reviewed on May 3, 2024

Angad Arts Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Clayton

St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $104
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.