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Hotels in St. Charles

Choose from 2362 St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
All good

Reviewed on Mar 24, 2026

Ameristar Casino Resort and Spa
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,002 reviews)
The staff was amazing! Just the room was a bit dirty and run down.

Reviewed on Mar 23, 2026

Comfort Suites St Charles - St Louis
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
  • 6 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
Extremely Clean & Comfortable an Professional.

Reviewed on Mar 23, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,001 reviews)
I didnt have a pet personally but i did see multiple dogs while i was there so it waa likely very pet friendly

Reviewed on Mar 23, 2026

Drury Plaza Hotel St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
  • 11 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
Breakfast was disappointing. Food was cold and the guy making the omlets was very rude to my husband and our daughter.

Reviewed on Mar 23, 2026

Embassy Suites by Hilton St. Louis St. Charles
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,359 reviews)
My kids loved it

Reviewed on Mar 24, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,889 reviews)
Air conditioning in multiple rooms didnt work. Fromt desk reset unit but onky lasted a few hours. Room was mid 70 by morning.

Reviewed on Mar 25, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,110 reviews)
Stay was wonderful. Would definitely recommend.

Reviewed on Mar 23, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,687 reviews)
Overall a great hotel, nice location, easy valet. It was inconvenient that an elevator was down, we waited for 5 cycles to run before we were able to get to the lobby around breakfast.

Reviewed on Mar 24, 2026

21C Museum Hotel St Louis
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 20 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,201 reviews)
Great hotel for the hockey tournament... very nice staff... great location. The air quality was poor nearing the casino and awful inside... otherwise a great stay

Reviewed on Mar 21, 2026

Hollywood Casino & Hotel St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,980 reviews)
Clean, friendly staff.

Reviewed on Mar 25, 2026

Hyatt Regency St. Louis at The Arch
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,352 reviews)
I stayed at Drury Inn and had a mixed experience. The staff was very nice and welcoming, and the extras offered were a great touch and definitely appreciated. However, there were several issues that made the stay disappointing. The hot tub and pool were both freezing and essentially unusable. The ...

Reviewed on Mar 25, 2026

Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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