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Hotels in St. Charles

Choose from 2281 St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,007 reviews)
All around great stay!

Reviewed on Dec 19, 2025

Ameristar Casino Resort and Spa
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street St. Charles MO
  • 7 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,000 reviews)
Nice room. No coffeemaker.

Reviewed on Dec 16, 2025

Best Western Plus The Charles Hotel
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
  • 7 min drive from Ameristar Casino St. Charles
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,003 reviews)
Very good

Reviewed on Dec 20, 2025

Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
  • 6 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
Everything was great!

Reviewed on Dec 22, 2025

Country Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
  • 11 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,009 reviews)
Excellent staff. Great room! Very clean. Amazing breakfast!

Reviewed on Dec 16, 2025

Embassy Suites by Hilton St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,006 reviews)
Nice stay

Reviewed on Dec 21, 2025

Drury Plaza Hotel St. Louis St. Charles
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (4,026 reviews)
It was fast and were able to accommodate a joining room for us.

Reviewed on Dec 20, 2025

Hyatt Regency St. Louis at The Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
  • 35 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,177 reviews)
Staff was so nice and helpful.

Reviewed on Dec 19, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
  • 35 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,169 reviews)
The lobby was beautiful, check-in was fast, and the room was great. There was no issue check-in of our cat and small dog.

Reviewed on Dec 23, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,281 reviews)
All is perfect except room cleanse

Reviewed on Dec 18, 2025

Drury Plaza Hotel St. Louis at the Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,508 reviews)
Clean room, nice linens, great view!

Reviewed on Dec 20, 2025

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,033 reviews)
Everything was Great!

Reviewed on Dec 22, 2025

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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