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Choose from 2245 St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,006 reviews)
Clean room, wonderful amenities

Reviewed on Nov 14, 2025

Ameristar Casino Resort and Spa
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
  • 7 min drive from Ameristar Casino St. Charles
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
7.8/10 Good! (1,002 reviews)
Comfortable and clean room. Would stay again

Reviewed on Nov 14, 2025

Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
  • 6 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
Room was very nice and clean! It smelled so good when we opened the door! Staff was great! Would definitely stay there again!

Reviewed on Nov 9, 2025

Country Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz, St. Charles, MO
  • 11 min walk from Ameristar Casino St. Charles
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,043 reviews)
Was very nice not to have to go out for dinner as they had a restaurant on the premises. Good service and good food.

Reviewed on Nov 11, 2025

Embassy Suites by Hilton St. Louis St. Charles
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St, St. Charles, MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,008 reviews)
Overall was fine. Breakfast service an refilling food was not great

Reviewed on Nov 11, 2025

Comfort Suites St Charles - St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,984 reviews)
Wonderful staff and great area. Accessible to so much in the area. Amazing bath tubs with remote and soaker tubs… 👍👍😎😎😍😍

Reviewed on Nov 11, 2025

Clayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
  • 35 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,088 reviews)
Clean Room Friendly Staff

Reviewed on Nov 10, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
  • 11 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,744 reviews)
room was clean, bed and pillows are comfortable, very nice staff and shuttle to the airport was quick

Reviewed on Nov 9, 2025

Pear Tree Inn St. Louis Airport
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
  • 31 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,216 reviews)
I arrived at almost 4 am after a long day at the hospital—my mom had surgery, & I just needed a few hours of real rest before heading back. Hotels.com and the front desk staff made it super easy to check in way before the normal 3 p.m. time, no hassle at all. The room was spotless, bed was so comfortable, ...

Reviewed on Nov 7, 2025

Forest Park Hotel by MDR
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,239 reviews)
Provided breakfast and dinner. Also three complimentary drinks at dinner!

Reviewed on Nov 14, 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,998 reviews)
Nice hotel close to the arch. Ruth steakhouse is right inside hotel. Staff pleasant

Reviewed on Nov 15, 2025

Hyatt Regency St. Louis at The Arch
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,276 reviews)
Staff was very attentive, friendly, available. Hotel was clean, gorgeous and architecturally beautiful. Breakfast offerings....thoughtful. Happy Hour offering with a meal was above and beyond. Loved everything about this hotel.

Reviewed on Nov 13, 2025

Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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