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Choose from 2427 St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,002 reviews)
"Upon arrival, we observed several cleanliness and maintenance issues in the room. The couch had visible spots and hair on it. There appeared to be red stains or residue on the curtains. Additionally, the toilet was not functioning properly. These conditions did not meet our expectations for cleanliness ..."

Reviewed on Jun 24, 2026

Ameristar Casino Resort and Spa
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
  • 7 min drive from Ameristar Casino St. Charles
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,001 reviews)
"Moisy and doing renovations now."

Reviewed on Jun 23, 2026

Hampton Inn St. Charles St. Peters
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,004 reviews)
"We loved our stay. The room was clean, the food was delicious, and the staff was friendly and explained everything in detail. We will definitely stay here again."

Reviewed on Jun 27, 2026

Drury Plaza Hotel St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
  • 11 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
"Beautiful hotel. Well maintained. Breakfast could be better. Housekeeping did not come to room everyday and we needed fresh towels. One night, there was a big group in the center lobby and the noise was so loud till 2:00am or later. Was difficult for my kids to sleep and hotel staff didn't ask them ..."

Reviewed on Jun 21, 2026

Embassy Suites by Hilton St. Louis St. Charles
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,154 reviews)
"Great room!"

Reviewed on Jun 26, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,250 reviews)
"Great place. Staff was very nice and helpful. Breakfast was really good . Parking was a bit confusing at first but is great to have parking. Not free on the weekends but still good."

Reviewed on Jun 27, 2026

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,520 reviews)
"Clean rooms, good breakfast, friendly staff"

Reviewed on Jun 27, 2026

Drury Plaza Hotel St. Louis at the Arch
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
  • 31 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,618 reviews)
"The area has homeless people and random people asking for the password to get into the hotel….floors were wet so much my feet were black. Did not feel safe."

Reviewed on Jun 27, 2026

Forest Park Hotel by MDR
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
  • 25 min drive from Ameristar Casino St. Charles
Book a stay at this boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ...
9/10 Wonderful! (1,978 reviews)
"Okay so all the reviews about your car being broken into, they should just offer a stay and break package because that is it guarantee that it's going to happen. I'm not sure who I'm more frustrated with, the St Louis PD who does nothing to stop this problem or care (still waiting for them to call ..."

Reviewed on Jun 25, 2026

Moonrise Hotel
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
  • 45 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,636 reviews)
"Fantastic property"

Reviewed on Jun 26, 2026

River City Casino & Hotel
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 20 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,193 reviews)
"Everyone there was Great!"

Reviewed on Jun 26, 2026

Hollywood Casino & Hotel St. Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (2,030 reviews)
"This property needs some major updates. It is old and dirty. The toilet in the room didn't work correctly. The only employee that was helpful was the friendly lady at the front desk. I wish I had caught her name she deserves recognition! All the other employees looked as if they hated their job and ..."

Reviewed on Jun 26, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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