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Hotels in Southern Illinois

Check Last Minute Southern Illinois Hotel Deals

Tonight Jul 1 - Jul 2This weekend Jul 1 - Jul 3

Choose from 653 Southern Illinois Hotel Deals

Motel 6 Caseyville, IL - Caseyville Il
Motel 6 Caseyville, IL - Caseyville Il
2 out of 5
2431 Old Country Inn Dr, Caseyville, IL, 62232
  • 4 hours drive from Shawnee National Forest
The price is $60 per night from Jul 29 to Jul 30
Stay at this business-friendly motel in Caseyville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the comfy rooms ...
Motel 6 Caseyville, IL - Caseyville Il
Drury Inn & Suites Mt. Vernon
Drury Inn & Suites Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL, 62864
  • 2 hours drive from Shawnee National Forest
The price is $130 per night from Jul 7 to Jul 8
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites Mt. Vernon
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL, 62269
  • 4 hours drive from Shawnee National Forest
The price is $108 per night from Jul 7 to Jul 8
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites St. Louis O'Fallon, IL
Super 8 by Wyndham Fairview Heights-St. Louis
Super 8 by Wyndham Fairview Heights-St. Louis
2 out of 5
45 Ludwig Dr, Fairview Heights, IL, 62208
  • 4 hours drive from Shawnee National Forest
The price is $60 per night from Jul 8 to Jul 9
Stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
Super 8 by Wyndham Fairview Heights-St. Louis
Best Western Troy Hotel
Best Western Troy Hotel
2.5 out of 5
2020 Formosa Drive, Troy, IL, 62294
  • 4 hours drive from Shawnee National Forest
The price is $85 per night from Jul 17 to Jul 18
Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Best Western Troy Hotel
Hampton Inn O'Fallon
Hampton Inn O'Fallon
2.5 out of 5
430 Regency Park, O'Fallon, IL, 62269
  • 4 hours drive from Shawnee National Forest
The price is $105 per night from Jul 19 to Jul 20
Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Hampton Inn O'Fallon
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
2.5 out of 5
6 Gateway Dr, Collinsville, IL, 62234
  • 4 hours drive from Shawnee National Forest
The price is $109 per night from Jul 5 to Jul 6
Stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy beds ...
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
2.5 out of 5
300 Potomac Blvd, Mount Vernon, IL, 62864
  • 2 hours drive from Shawnee National Forest
The price is $129 per night from Jul 28 to Jul 29
Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis Area
2 out of 5
910 Edwardsville Rd, Troy, IL, 62294
  • 4 hours drive from Shawnee National Forest
The price is $76 per night from Jul 3 to Jul 4
Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Super 8 by Wyndham Troy IL/St. Louis Area
La Quinta Inn & Suites by Wyndham Pontoon Beach
La Quinta Inn & Suites by Wyndham Pontoon Beach
2.5 out of 5
14 Regency Park Dr, Granite City, IL, 62040
  • 4 hours drive from Shawnee National Forest
The price is $99 per night from Jul 6 to Jul 7
Stay at this business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the comfy rooms and the overall value ...
La Quinta Inn & Suites by Wyndham Pontoon Beach
Comfort Suites Mount Vernon
Comfort Suites Mount Vernon
2.5 out of 5
404 South 44th Street, Mount Vernon, IL, 62864
  • 2 hours drive from Shawnee National Forest
The price is $104 per night from Jul 4 to Jul 5
Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Suites Mount Vernon
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL, 62208
  • 4 hours drive from Shawnee National Forest
The price is $103 per night from Jul 19 to Jul 20
Stay at this 3-star business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites St. Louis Fairview Heights
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southern Illinois

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southern Illinois hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Illinois.

Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Illinois’s 653 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $60. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southern Illinois hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Illinois. No matter your reason for visiting Southern Illinois, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Illinois hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Illinois for as low as $60.

How many hotels are there in Southern Illinois?

With over 653 hotels in Southern Illinois, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $60.

How to find cheap car rentals in Southern Illinois?

Finding a cheap car rental deal in Southern Illinois is as easy as scoring cheap hotels in Southern Illinois. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southern Illinois now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southern Illinois right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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