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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Interior
Suite, 1 King Bed (Library) | 1 bedroom, in-room safe, desk, laptop workspace
Loft, 2 Queen Beds | 1 bedroom, in-room safe, desk, laptop workspace
Dining
Billiards

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
$178
includes taxes & fees
Nov 23 - Nov 24

Explore the area

View in a map
1528 Locust street, St. Louis, MO, 63103
  • Place, St. Louis Union Station
    ‪6 min walk‬
  • Place, Enterprise Center
    ‪6 min walk‬
  • Place, Busch Stadium
    ‪14 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪21 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(76 reviews)
  • 309 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | 1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(22 reviews)
  • 423 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 237 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Loft, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Loft, 2 Queen Beds

  • 431 sq ft
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, Accessible (Accessible)

  • 269 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed (21C)

  • 1119 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed (Library)

  • 732 sq ft
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Luxury Suite, 1 King Bed

  • 549 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 Double Bed, Accessible

  • 388 sq ft
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 Double Bed, Accessible

  • 517 sq ft
  • Sleeps 2
  • 1 Double Bed

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About this property

21C Museum Hotel St Louis

4.5-star hotel in Downtown West
This smoke-free hotel features an indoor pool, a restaurant, and a fitness center. WiFi in public areas is free. Additionally, a bar/lounge, a steam room, and a coffee shop/cafe are onsite. Change of towels is available on request.
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
In addition to an indoor pool, 21C Museum Hotel St Louis provides a steam room and a fitness center. Dining options at the hotel include a restaurant and a coffee shop/cafe. A bar/lounge is on site where guests can unwind with a drink. Public areas are equipped with complimentary wireless Internet access.

Business-related amenities at this 4.5-star property consist of a business center and meeting rooms. This luxury hotel also offers spa services, a vending machine, and concierge services. Parking is available onsite for a surcharge.

21C Museum Hotel St Louis is a smoke-free property.

Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Reviews

21C Museum Hotel St Louis Reviews

9.0

Wonderful

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness
Rating 10 - Excellent. 1030 out of 1432 reviews
Rating 8 - Good. 211 out of 1432 reviews
Rating 6 - Okay. 93 out of 1432 reviews
Rating 4 - Poor. 44 out of 1432 reviews
Rating 2 - Terrible. 54 out of 1432 reviews

Reviews

10/10 Excellent

Jamie

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jul 2025

10/10 Excellent

Frank

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great gym and pool.
Stayed 3 nights in Apr 2025

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025

4/10 Poor

Kyle

Traveled with family and small children
Liked: Property conditions & facilities
Disliked: Cleanliness, staff & service
The property was beautiful but we did not have a good experience. There were wrappers in the hallway on the 4th floor and it looked dirty. That evening an employee opened and came all the way into our room with his key card and it freaked us out, we never found out why that happened. He just ran out the door without saying anything. The next day, the fire alarms went off multiple times and we had to go down to street level and hang out in the lobby area for 45 minutes until the firefighters declared it a false alarm. We wanted to go to the bar and get some drinks, there was nobody at the hostess station so we sat down until the bartender very rudely told us we had to wait to be seated. I asked about going to the museum and I was told that it was closed due to a private event. I asked if I could go the next morning and the front desk employee told me I could go very early because they had another event the next day too. I asked if 6am would be alright and they said yes. I woke up specifically to go see the museum and the main gallery had already been closed for the event. We were also told the pool opened at 5am but my husband went down at 5:15am and it was closed. The hotel is nice but it just feels like it has some pretty big management issues. The room was nice though and the girl who did the valet parking (a young woman wearing knee braces both times we saw her) was very friendly and efficient! Coffee at the cafe spot was great as well.
Stayed 2 nights in Jul 2025

4/10 Poor

Celeste

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service
Check in was horrible. We arrived around midnight, with no reservation. Unbeknown to us, there were a few events happening that weekend and almost all hotels were booked full. We were grateful to have found this hotel. However, at check in, the
Stayed 1 night in Jul 2025

8/10 Good

Liz

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jul 2025

10/10 Excellent

Joseph

Stayed 3 nights in Jul 2025

8/10 Good

Angela

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel. I always enjoying seeking out and finding a 21C. The vibe was inviting and creative. Beautiful works of art. Loved the pool and gym/sauna/steam room area. We will stay again.
Stayed 1 night in Jul 2025

10/10 Excellent

Tedtra

Stayed 1 night in Jul 2025

10/10 Excellent

Bruce

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Art Deco at its Finest

This has been one of the best hotels I've been to in several years. Beautiful and clean with the the most beautiful art work around the whole hotel and the fact that it has its own Art Gallery is absolutely amazing.
Stayed 1 night in Jul 2025

10/10 Excellent

Trenicia

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved it! No complaints
Stayed 2 nights in Jul 2025

6/10 Okay

Bill

Traveled with family
Disliked: Amenities
The property was unique, breakfast at cafe was good. The bad, the first valet was not helpful at all , the front desk people were not helpful, when we got to our rooms my room still had food in the refrigerator and it was broke. The room was extremely hot because the a/c was off . Went to take a shower that night and the shower button was broke the drain was broke . Told front desk and they didn’t seem to concerned said that they’d heard there were some issues with some rooms. Overall for the money would not stay again
Stayed 4 nights in Jul 2025

10/10 Excellent

Sean

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Ashley

Stayed 1 night in Jul 2025

6/10 Okay

Melissa

Traveled with family
Definitely no attention to detail with cleanliness. Robes so wrinkled and cheap looking didn’t even want to use them. Carpets stained horribly in the hallways. Bathroom not properly wiped down.
Stayed 1 night in Jul 2025

6/10 Okay

Nicole

Liked: Staff & service
Disliked: Cleanliness

Cool vibe

Cool atmosphere and vibe, however, the room was not the cleanest. Towels had stains on them, bedding as well. There were giant cobwebs in the vents and we didn't get clean towels when they cleaned the room.
Stayed 3 nights in Jul 2025

10/10 Excellent

Randall

Stayed 2 nights in Jul 2025

10/10 Excellent

Julie

Business traveler, Traveled with partner
Liked: Amenities
Everything about this hotel was magical! Food is fove star service people rooms. Saunna workout room and it's beautiful!
Stayed 2 nights in Jul 2025

10/10 Excellent

Rebecca

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kevin was especially helpful and good to find a fellow LFC supporter !
Stayed 2 nights in Jul 2025

10/10 Excellent

Michael

Stayed 1 night in Jul 2025

10/10 Excellent

Lindsay

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Jul 2025

6/10 Okay

Randy

Stayed 3 nights in Jul 2025

10/10 Excellent

Lynne

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

rebecca

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great location
Stayed 1 night in Jun 2025

10/10 Excellent

Shauna

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Jun 2025