Hotels Near
Mission Bay

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Featured Mission Bay Hotels

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (3,923 reviews)
Exceptional service! Amazingly helpful and kind staff. Practical guest laundry self-service - vey necessary on a long trip. Highly recommend Dana Hotel.

Reviewed on Dec 15, 2025

The Dana on Mission Bay
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,311 reviews)
Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!

Reviewed on Dec 14, 2025

San Diego Mission Bay Resort
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,353 reviews)
Paradies Point feels a bit like high end camping with large, nice rooms that need a bit of improvement here and there. The staff is young and not very hospitable - just doing their jobs. Expensive food and drinks - $500 for two appetizers, sandwiches and drinks for 4 plus a infant. Rooms are expensive ...

Reviewed on Dec 14, 2025

Paradise Point Resort & Spa
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,570 reviews)
Beautiful property right on the water. I will be back.

Reviewed on Dec 11, 2025

Hyatt Regency Mission Bay Spa and Marina
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,180 reviews)
Yes , nicest hotel I have ever seen

Reviewed on Dec 15, 2025

Sheraton San Diego Resort
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,328 reviews)
The hotel is big on charm and decor. It was in 1937 and the guest rooms haven’t been enlarged or highly modernized. What they did get is a big dash of kitsch. Clashing wall paper, canopied beds, retro appliances, and a huge room bar (you pay per drink). We took a second floor poolside room with a ...

Reviewed on Dec 11, 2025

Lafayette Hotel & Club
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (740 reviews)
Good place. Easy to get around and clean.

Reviewed on Dec 15, 2025

The DEXTRO Little Italy, BW Premier Collection
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,952 reviews)
Very well and clean

Reviewed on Dec 12, 2025

Legacy Resort Hotel & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
8.8/10 Excellent! (3,151 reviews)
the staff was very accommodating and the food options nearby were all very delicious!

Reviewed on Dec 15, 2025

Hard Rock Hotel San Diego
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr National City CA
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (3,538 reviews)
⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️

Reviewed on Dec 16, 2025

Best Western Plus Marina Gateway Hotel
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
8.4/10 Very Good! (2,180 reviews)
We had a great stay! Everything was clean and the staff was phenomenal!!

Reviewed on Dec 14, 2025

San Diego Marriott La Jolla
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (100 reviews)
Clean rooms, friendly staff

Reviewed on Dec 15, 2025

Courtyard by Marriott San Diego Downtown Little Italy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Mission Bay

San Diego is a city that has a lot going on, but you have your sights set on Mission Bay. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Mission Bay has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Mission Bay hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of San Diego so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Mission Bay underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Mission Bay city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Mission Bay cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Mission Bay at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $124
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Mission Bay hotel you want, book it, and never look back. Because your great escape is ahead of you.