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Hotels in San Ysidro

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Choose from 5978 San Ysidro Hotel Deals

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
  • 37 min drive from San Ysidro Border Crossing
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,910 reviews)
"Over Really Great experience. Only complaint waa the bed was a wasn't the best and Pillows were Uncomfortable for me personally. Pool was fantastic loved the night right"

Reviewed on Jul 31, 2025

Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
  • 30 min drive from San Ysidro Border Crossing
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,777 reviews)
"Water pressure was the best I’ve had."

Reviewed on Aug 2, 2025

Wyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy, San Diego, CA
  • 29 min drive from San Ysidro Border Crossing
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,321 reviews)
"The hotel is really good but there are lots of surcharges that makes me decide not to go back in this hotel. Embassy Suite is always nice, but this branch is the least on my lists."

Reviewed on Jul 30, 2025

Embassy Suites by Hilton San Diego Bay Downtown
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
  • 29 min drive from San Ysidro Border Crossing
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,778 reviews)
"Loved loved loved how clean it was! This is the second time staying at a Hyatt hotel and it didn’t disappoint. Will continue to stay at many more of their locations."

Reviewed on Aug 1, 2025

Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
  • 39 min drive from San Ysidro Border Crossing
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,607 reviews)
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Reviewed on Aug 3, 2025

The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
  • 29 min drive from San Ysidro Border Crossing
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,787 reviews)
"Everything was great--exceeded expectations."

Reviewed on Aug 1, 2025

Marriott Marquis San Diego Marina
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
1 Park Blvd, San Diego, CA
  • 28 min drive from San Ysidro Border Crossing
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (1,617 reviews)
"Great location and friendly staff"

Reviewed on Aug 1, 2025

Hilton San Diego Bayfront
Dextro, Little Italy, BW Premier Collection

Dextro, Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
  • 31 min drive from San Ysidro Border Crossing
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
7.6/10 Good! (1,035 reviews)
"Elijah was amazing and very accommodating as a front desk worker! The room was clean and comfortable. I will be staying here again and recommending this location to friends."

Reviewed on Jul 31, 2025

Dextro, Little Italy, BW Premier Collection
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
  • 37 min drive from San Ysidro Border Crossing
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,155 reviews)
"Everything was great except why we have to pay for parking."

Reviewed on Jul 30, 2025

Hampton Inn San Diego/Mission Valley
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
  • 37 min drive from San Ysidro Border Crossing
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,900 reviews)
"Parking is difficult and tight...gotta re paint the lines and give more room to park"

Reviewed on Aug 3, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
  • 31 min drive from San Ysidro Border Crossing
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (2,758 reviews)
"The staff is very friendly and helpful. We had a small issue with the AC in our room and they handled it right away and resolved the issue quickly. The rest of the weekend was great with our stay!"

Reviewed on Aug 3, 2025

Bay Club Hotel & Marina
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
  • 38 min drive from San Ysidro Border Crossing
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,468 reviews)
"Customer service, beds and sheets wonderful. Amazing view from room. Good location."

Reviewed on Aug 2, 2025

Sheraton Mission Valley San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Ysidro

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $128. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Ysidro hotel deals at the last minute.

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Frequently Asked Questions About San Ysidro hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in San Ysidro?

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How to find cheap car rentals in San Ysidro?

Finding a cheap car rental deal in San Ysidro is as easy as scoring cheap hotels in San Ysidro. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.