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Hotels in National City

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Choose from 7546 National City Hotel Deals

Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel
3.5 out of 5
800 Bay Marina Dr, National City, CA
  • 4 min drive from Paradise Valley Medical Center
The price is $158 per night from Mar 30 to Mar 31
$158
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star eco-certified hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (3,063 reviews)
"Clean, quiet and professional staff! When back in San Diego, Im staying here."

Reviewed on Mar 15, 2025

Best Western Plus Marina Gateway Hotel
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
  • 16 min drive from Paradise Valley Medical Center
The price is $202 per night from Mar 23 to Mar 24
$202
includes taxes & fees
Mar 23 - Mar 24
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,276 reviews)
"We loved the walking paths around the property as well as the pool. The rooms were pretty nice, but there wasn’t a fan in the bathroom—just a window with a plantation shutter that opens to the outside (where people could technically walk past and see you in the bathroom), so that was weird. It also ..."

Reviewed on Mar 16, 2025

The Dana on Mission Bay
San Diego Marriott La Jolla
San Diego Marriott La Jolla
4 out of 5
4240 La Jolla Village Dr, La Jolla, CA
  • 32 min drive from Paradise Valley Medical Center
The price is $171 per night from Mar 30 to Mar 31
$171
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (1,639 reviews)
"Acceptable , but parking is very expensive"

Reviewed on Mar 15, 2025

San Diego Marriott La Jolla
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
  • 14 min drive from Paradise Valley Medical Center
The price is $160 per night from Mar 24 to Mar 25
$160
includes taxes & fees
Mar 24 - Mar 25
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,351 reviews)
"It was a great stay. Everyone was friendly, helpful and hospitable."

Reviewed on Mar 16, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
  • 17 min drive from Paradise Valley Medical Center
The price is $269 per night from Mar 23 to Mar 24
$269
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,147 reviews)
"Beautiful resort. We were in the tower on the top floor facing the highway so it was constantly loud with those sounds when on the balcony. The room was quiet, and the staff very accommodating when it came to daily service. Their Spa Breeza was to die for. I really loved being pampered and my massage ..."

Reviewed on Mar 8, 2025

San Diego Mission Bay Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
  • 8 min drive from Paradise Valley Medical Center
The price is $171 per night from Apr 13 to Apr 14
$171
includes taxes & fees
Apr 13 - Apr 14
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,616 reviews)
"This was our first time staying in San Diego and I’m happy I chose for us to stay here! Great room, great views, the only small thing that my wife didn’t like but it really didn’t disrupt her is that it’s close to San Diego Airport so you can hear the takeoffs all night but it wasn’t enough for us ..."

Reviewed on Mar 17, 2025

Wyndham San Diego Bayside
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
  • 13 min drive from Paradise Valley Medical Center
The price is $127 per night from Mar 31 to Apr 1
$127
includes taxes & fees
Mar 31 - Apr 1
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,764 reviews)
"There was a construction 🚧"

Reviewed on Mar 17, 2025

Comfort Inn Sea World Area
Inn By The Sea La Jolla
Inn By The Sea La Jolla
3.5 out of 5
7830 Fay Ave, La Jolla, CA
  • 28 min drive from Paradise Valley Medical Center
The price is $233 per night from Mar 30 to Mar 31
$233
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star hotel in La Jolla. Enjoy free WiFi, room service, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,482 reviews)
"Home away from home:)"

Reviewed on Mar 14, 2025

Inn By The Sea La Jolla
Humphreys Half Moon Inn
Humphreys Half Moon Inn
3.5 out of 5
2303 Shelter Island Dr, San Diego, CA
  • 9 min drive from Paradise Valley Medical Center
The price is $191 per night from Apr 13 to Apr 14
$191
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in San Diego. Enjoy a marina, a nightclub, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9/10 Wonderful! (2,193 reviews)
"Nice room and nice grounds with great atmosphere."

Reviewed on Mar 14, 2025

Humphreys Half Moon Inn
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
  • 9 min drive from Paradise Valley Medical Center
The price is $231 per night from Mar 26 to Mar 27
$231
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,568 reviews)
"Excellent"

Reviewed on Mar 16, 2025

Sheraton San Diego Resort
The Little Italy Hotel Downtown San Diego
The Little Italy Hotel Downtown San Diego
4 out of 5
1646 Front St, San Diego, CA
  • 8 min drive from Paradise Valley Medical Center
The price is $157 per night from Mar 20 to Mar 21
$157
includes taxes & fees
Mar 20 - Mar 21
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
7.6/10 Good! (1,012 reviews)
"Fantastic"

Reviewed on Mar 15, 2025

The Little Italy Hotel Downtown San Diego
Omni San Diego Hotel
Omni San Diego Hotel
4 out of 5
675 L St, San Diego, CA
  • 6 min drive from Paradise Valley Medical Center
The price is $277 per night from Apr 18 to Apr 19
$277
includes taxes & fees
Apr 18 - Apr 19
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9/10 Wonderful! (1,893 reviews)
3 day weekend at the Omni
"The Omni never disappoints!! Amazing service and the view from room 1909 , to die for"

Reviewed on Mar 18, 2025

Omni San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in National City

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in National City.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of National City’s 7,546 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $127. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great National City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in National City. No matter your reason for visiting National City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About National City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in National City for as low as $127.

How many hotels are there in National City?

With over 7,546 hotels in National City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $127.

How to find cheap car rentals in National City?

Finding a cheap car rental deal in National City is as easy as scoring cheap hotels in National City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.