Hotels Near
Clayton

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured Clayton Hotels

Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,124 reviews)
"Very nice!"

Reviewed on Nov 25, 2023

Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,636 reviews)
"Great value"

Reviewed on Nov 27, 2023

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
4 out of 5
7730 Bonhomme Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast, and WiFi. Popular attractions St. Louis Zoo and Saint Louis Galleria ...
8.8/10 Excellent! (408 reviews)
"the area was great and convenient to everything. The accomodations and the staff were superb!"

Reviewed on Nov 10, 2023

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5 out of 5
100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in St. Louis. Enjoy breakfast, WiFi, and room service. Our guests praise the room service in our reviews. Popular attractions ...
9.2/10 Wonderful! (495 reviews)
"I expected to see a shuttle from the airport -- or at least advice about the location of a taxi dispatcher and approximate fee for the taxi. More importantly, I was not aware that the MetroLink service maintains a stop immediately behind the hotel and would have cost me about a tenth as much as the ..."

Reviewed on Oct 28, 2023

The Ritz-Carlton, St. Louis
Homewood Suites by Hilton St Louis - Galleria
Homewood Suites by Hilton St Louis - Galleria
3 out of 5
8040 Clayton Road, Richmond Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,000 reviews)
"This hotel surpasses my expectations. It is so clean and spacious. It has kitchen and stoves and everything I needed. The breakfast was amazing with a lot of healthy foods.. I will definitely recommend it for people."

Reviewed on Nov 20, 2023

Homewood Suites by Hilton St Louis - Galleria
Residence Inn By Marriott St. Louis Clayton
Residence Inn By Marriott St. Louis Clayton
3 out of 5
8125 Forsyth Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and valet parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (48 reviews)
"This hotel looks new and is super clean. Our room was huge and comfortable. Breakfast was delicious (hot) and staff was friendly and helpful."

Reviewed on Nov 21, 2023

Residence Inn By Marriott St. Louis Clayton
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundable
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (2,862 reviews)
"This was my second time staying and well I was gonna add a picture but I’m unable to but I had a few issues with my room as my bath didn’t work at first just the shower then they fixed that and I got in the tub and realized the putter shell was stripping off so flakes of paint were floating with ..."

Reviewed on Nov 28, 2023

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,050 reviews)
"This was a great stay overall! I had never stayed at a Drury Plaza before and was unsure what to expect. I was pleasantly surprised. The only down fall was the lack of a restaurant that was kid friendly and it was difficult to make the most of "happy hour" due to the crowds, but it was a perk and ..."

Reviewed on Nov 27, 2023

Drury Plaza Hotel St. Louis at the Arch
Moonrise Hotel
Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the bar and the helpful staff in our reviews. ...
9/10 Wonderful! (1,048 reviews)
"Great property"

Reviewed on Nov 27, 2023

Moonrise Hotel
Hilton St. Louis at the Ballpark
Hilton St. Louis at the Ballpark
4 out of 5
1 S Broadway, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the helpful staff and ...
7.4/10 Good! (1,000 reviews)
"Only problem was sitting on the street for 20 minutes to use the Valet service. Need to figure out a better way."

Reviewed on Nov 18, 2023

Hilton St. Louis at the Ballpark
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
1820 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,003 reviews)
"The staff was great, the rooms clean and comfortable"

Reviewed on Nov 20, 2023

St. Louis Union Station Hotel, Curio Collection by Hilton
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in St. Louis. Enjoy free WiFi, breakfast, and valet parking. Popular attractions St. Louis Union Station and Dome at America’s Center ...
9.2/10 Wonderful! (105 reviews)
"I like the building and how it was repurposed. I like the art work."

Reviewed on Nov 29, 2023

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Clayton

St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $96
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.