Hotels Near
Clayton

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Featured Clayton Hotels

Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,920 reviews)
"Very clean hotel with easy check in. Surprised and disappointed there was no coffee station available in the lobby. We were permitted to check in at 2 pm."

Reviewed on Jul 8, 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton
AC Hotel St. Louis Clayton
3 out of 5
227 South Central Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (89 reviews)
"Had a two-night stay around the 4th of July. Great location and nice, contemporary building and rooms. Walkable to food and dining places around the Clayton area, and very close to The Hill and the museums. Highly recommended!"

Reviewed on Jul 7, 2025

AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3 out of 5
216 N Meramec Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (856 reviews)
"Fantastic location. The on site bar was friendly and served delicious cocktails. Will be back!"

Reviewed on Jul 7, 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,837 reviews)
Excellent View of the Arch
"Hotel was literally at the Arch. Our room had an excellent front view of the St Louis Arch. We watched the 4th of July celebration from our room. The hotel was also walking distance to St Louis Cardinals baseball stadium and many restaurants."

Reviewed on Jul 6, 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,821 reviews)
"My husband and I decided to come to St. Louis for the 4th, and I'm glad that I booked a room here. It is the most convenient location, next to the Gateway Arch and also walking distance to Ballpark Village where there are restaurants to choose from. The bed was comfortable and the bathroom was pretty ..."

Reviewed on Jul 6, 2025

Drury Plaza Hotel St. Louis at the Arch
The Arch Convention Hotel
The Arch Convention Hotel
3.5 out of 5
811 N 9th Street, St. Louis, MO
Fully refundable
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
7/10 Good! (1,011 reviews)
"Let me start by saying that the staff was amazing. Front desk helped me with issues that I found with the room (smelled like cigarette smoke and closet door handle broke off). The hotel really needs to be updated due to wear and tear."

Reviewed on Jul 4, 2025

The Arch Convention Hotel
Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,477 reviews)
"Great stay"

Reviewed on Jul 5, 2025

Pear Tree Inn St. Louis Near Union Station
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,012 reviews)
"Served its purpose for our needs"

Reviewed on Jul 6, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Moonrise Hotel
Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
9/10 Wonderful! (1,783 reviews)
"I would 100% stay at the Moonrise Hotel again. The Delmar Loop was a great place to explore as a tourist in St. Louis. I loved the theme of this hotel, every nook and cranny was decorated with something cute. The room was clean and had everything we needed. Parking was easier than expected in the ..."

Reviewed on Jul 7, 2025

Moonrise Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
8.6/10 Excellent! (1,006 reviews)
"The whole staff was super nice since we first contacted them with questions prior to staying . They made us and our dog Athena feel super"

Reviewed on Jul 5, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,949 reviews)
Clean and nice.
"Really great place to stay."

Reviewed on Jul 5, 2025

Hollywood Casino & Hotel St. Louis
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,227 reviews)
"Excellent service"

Reviewed on Jul 8, 2025

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Clayton

St. Louis is a city that has a lot going on, but you have your sights set on Clayton. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Clayton has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Clayton hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Clayton underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Clayton city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Clayton cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Clayton at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $109
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Clayton hotel you want, book it, and never look back. Because your great escape is ahead of you.