Hotels Near
Central West End

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Featured Central West End Hotels

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in ...
9/10 Wonderful! (1,010 reviews)
"Nice hotel highly recommended"

Reviewed on Jun 5, 2026

The Royal Sonesta Chase Park Plaza St. Louis
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,002 reviews)
"Na"

Reviewed on Jun 3, 2026

DoubleTree by Hilton St. Louis Forest Park
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions St. Louis Zoo and St. Louis Union Station ...
8.6/10 Excellent! (541 reviews)
"Clean rooms. Staff was prompt with things."

Reviewed on Jun 6, 2026

The West End
Aloft by Marriott St. Louis Cortex

Aloft by Marriott St. Louis Cortex

3 out of 5
4245 Duncan Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (935 reviews)
"A nice stay however the valet service charged us for 4 days when we were only there for 2 days. I got the receipt in my email 2 days later. Property is nice and close enough to the busier parts of the city."

Reviewed on Jun 4, 2026

Aloft by Marriott St. Louis Cortex
Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG

3.5 out of 5
4630 Lindell St. Louis MO
Fully refundable
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 4 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,013 reviews)
"Tasteful and clean"

Reviewed on Jun 6, 2026

Hotel Indigo St Louis - Central West End by IHG
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (762 reviews)
"Great stay. Was able to navigate the area just fine. The staff was kind and helpful."

Reviewed on Jun 6, 2026

AC Hotel St. Louis Central West End
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,100 reviews)
"Hotel staff was friendly and room was very clean"

Reviewed on Jun 7, 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (2,006 reviews)
"Very clean, friendly staff,breakfast big variety,convient location,I will stay again"

Reviewed on Jun 7, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,228 reviews)
"Garage parking is free on weekends"

Reviewed on Jun 7, 2026

Clayton Plaza Hotel & Extended Stay
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,341 reviews)
"We enjoyed our overnight stay and breakfast very much! The room was clean and the beds were comfortable. Breakfast was very good, with a variety of choices."

Reviewed on Jun 6, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (3,003 reviews)
"Good place! Great staff. I'll be back."

Reviewed on Jun 7, 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,486 reviews)
"We had a nice visit, it was clean, close to our destination. Bed was comfortable and we look forward to returning so we can enjoy the amenities a little more our next visit."

Reviewed on Jun 7, 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Central West End

St. Louis is a city that has a lot going on, but you have your sights set on Central West End. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Central West End has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Central West End hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Central West End underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Central West End city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Central West End cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Central West End at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $106
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Central West End hotel you want, book it, and never look back. Because your great escape is ahead of you.