Hotels Near
East Florence

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Featured East Florence Hotels

Renaissance Shoals Resort and Spa

Renaissance Shoals Resort and Spa

3.5 out of 5
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (754 reviews)
The staff was excellent! We made it out of the ice storm in MS. We had no powe and no water with a 5 month old and 3 year old. The staff was so accommodating. So thankful for this beautiful Resort to take shelter in. Thank you all!

Reviewed on Jan 27, 2026

Renaissance Shoals Resort and Spa
Residence Inn Florence Marriott

Residence Inn Florence Marriott

3 out of 5
1000 Sweetwater Ave Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (330 reviews)
The room was great!

Reviewed on Nov 29, 2025

Residence Inn Florence Marriott
Budget Inn & Suites

Budget Inn & Suites

2.5 out of 5
1238 Florence Boulevard Florence AL
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (148 reviews)
Good enough for the price.

Reviewed on Jan 17, 2026

Budget Inn & Suites
The ColdWater Inn

The ColdWater Inn

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (681 reviews)
The front desk staff was extremely friendly

Reviewed on Jan 27, 2026

The ColdWater Inn
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (816 reviews)
Nice staff clean. Might want to bring ear plugs as you can hear people in halls and neighboring rooms.

Reviewed on Jan 19, 2026

The Stricklin Hotel
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,003 reviews)
Clean and comfortable.

Reviewed on Jan 24, 2026

Days Inn by Wyndham Muscle Shoals Florence
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (972 reviews)
The room was clean bed was comfortable and the staff was friendly and helpful.

Reviewed on Jan 19, 2026

Clarion Inn Sheffield Muscle Shoals
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (767 reviews)
Nice clean room.

Reviewed on Jan 14, 2026

Comfort Suites Florence Shoals Area
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (595 reviews)
Clean room and courteous staff!

Reviewed on Jan 14, 2026

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.2/10 Good! (901 reviews)
Good stay. Clean room. Front desk friendly and efficient.

Reviewed on Jan 21, 2026

Baymont by Wyndham Florence/Muscle Shoals
Red Roof Inn Muscle Shoals

Red Roof Inn Muscle Shoals

2.5 out of 5
2807 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fame Recording Studios and ...
6.6/10 (303 reviews)
Courteous staff nice room

Reviewed on Jan 22, 2026

Red Roof Inn Muscle Shoals
Hampton Inn & Suites Florence-Downtown

Hampton Inn & Suites Florence-Downtown

2.5 out of 5
505 S Court St Florence AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (704 reviews)
The hotel was great. Also, this place shares a parking lot with a Taco Bell. I definitely lived mas.

Reviewed on Jan 16, 2026

Hampton Inn & Suites Florence-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East Florence

Florence is a city that has a lot going on, but you have your sights set on East Florence. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East Florence has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East Florence hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East Florence underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the East Florence city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East Florence cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in East Florence at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $73
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the East Florence hotel you want, book it, and never look back. Because your great escape is ahead of you.