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Florence

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Florence Flights as Low as $410

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Florence

Fall in love at first flight with your vacation to Florence by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Florence on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Florence, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Florence

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Florence with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MSL airport.

What is the cheapest month to fly to Florence?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Florence are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Florence?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Florence.

What airport is best to fly into Florence?

When you’re planning your trip to Florence, convenience is the name of the game. Luckily, Florence Northwest Alabama Regional Airport is nearby so you can deplane and get going on checking off everything on your Florence must-do list.

How much are flights to Florence?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Florence on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $410, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Florence?

The trick to saving a stack of cash on your flight to Florence? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $410 right now, why wait?

Florence Flight Information
Destination airport
Florence
Destination airport IATA code
MSL

Last Minute Hotel Deals in Florence

The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (825 reviews)
Yes

Reviewed on Feb 20, 2026

The Stricklin Hotel
Renaissance Shoals Resort and Spa

Renaissance Shoals Resort and Spa

3.5 out of 5
10 Hightower Place Florence AL
Book a stay at this spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (758 reviews)
Lively atmosphere made for a fun stay but the hotel never seemed too crowded.

Reviewed on Feb 16, 2026

Renaissance Shoals Resort and Spa
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (778 reviews)
Very clean

Reviewed on Feb 19, 2026

Comfort Suites Florence Shoals Area
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.2/10 Good! (903 reviews)
Good stay. Clean room. Front desk friendly and efficient.

Reviewed on Jan 21, 2026

Baymont by Wyndham Florence/Muscle Shoals
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (601 reviews)
It was a great stay-we will be back t

Reviewed on Feb 16, 2026

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Hampton Inn & Suites Florence-Downtown

Hampton Inn & Suites Florence-Downtown

2.5 out of 5
505 S Court St Florence AL
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (706 reviews)
Clean room, great location.

Reviewed on Feb 7, 2026

Hampton Inn & Suites Florence-Downtown
Residence Inn Florence Marriott

Residence Inn Florence Marriott

3 out of 5
1000 Sweetwater Ave Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (332 reviews)
The room was great!

Reviewed on Nov 29, 2025

Residence Inn Florence Marriott
GunRunner Boutique Hotel

GunRunner Boutique Hotel

3.5 out of 5
310 E Tennessee St Florence AL
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (191 reviews)
Flawless execution by the Gunrunner staff from beginning to end! The pre-arrival instructions were spot-on. Our room was clean and personalized for us when we arrived (they had left us a gift of wine and a card congratulating us for our wedding anniversary that we were there celebrating - nice touch!). ...

Reviewed on Feb 6, 2026

GunRunner Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.