Hotels Near
Medical Center

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Featured Medical Center Hotels

Atheneum Suite Hotel
Atheneum Suite Hotel
4 out of 5
1000 Brush Avenue, Detroit, MI
Book a stay at this boutique hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the bar and the helpful staff ...
9/10 Wonderful! (1,827 reviews)
"With Greektown being under construction it would be great if the hotel actively offered and advertised a shuttle to the stadium area for games. The rooms are showing their age with outdated decor especially in the sitting area of the suites"

Reviewed on Jun 30, 2025

Atheneum Suite Hotel
Hollywood Casino at Greektown
Hollywood Casino at Greektown
4 out of 5
1200 Saint Antoine St, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Detroit. Enjoy free WiFi, 5 restaurants, and a casino. Our guests praise the helpful staff and the convenient ...
8.6/10 Excellent! (4,084 reviews)
"Great facility!"

Reviewed on Jul 4, 2025

Hollywood Casino at Greektown
The Siren Hotel, an Ash Hotel
The Siren Hotel, an Ash Hotel
4 out of 5
1509 Broadway St., Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Detroit. Enjoy free WiFi, 3 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in our ...
8.8/10 Excellent! (1,550 reviews)
"Good"

Reviewed on Jul 5, 2025

The Siren Hotel, an Ash Hotel
MotorCity Casino Hotel
MotorCity Casino Hotel
4.5 out of 5
2901 Grand River Ave, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Detroit. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (3,841 reviews)
"Nice clean hotel with friendly knowledgeable staff. Great gaming and dining options. Overall great place to stay and play."

Reviewed on Jul 2, 2025

MotorCity Casino Hotel
Hotel Indigo Detroit Downtown by IHG
Hotel Indigo Detroit Downtown by IHG
3.5 out of 5
1020 Washington Blvd, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
7.8/10 Good! (1,001 reviews)
"Good day. Had some trouble parking an oversized vehicle."

Reviewed on Jul 2, 2025

Hotel Indigo Detroit Downtown by IHG
Fort Pontchartrain Detroit, a Wyndham Hotel
Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 out of 5
2 Washington Blvd, Detroit, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
8.2/10 Very Good! (2,111 reviews)
"Check in was smooth and easy. Teresa was amazing and so were all the staff"

Reviewed on Jul 5, 2025

Fort Pontchartrain Detroit, a Wyndham Hotel
Baymont by Wyndham Downtown Detroit
Baymont by Wyndham Downtown Detroit
2.5 out of 5
3250 East Jefferson Ave., Detroit, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Detroit. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.8/10 (1,021 reviews)
Quick trip stay
"Came for a concert and a nice place to lay my head afterwards. My stay was all I hoped For and needed. Thank you for being a great establishment with amazing staff! 10/10 recommend!"

Reviewed on Jul 2, 2025

Baymont by Wyndham Downtown Detroit
The Godfrey Detroit, Curio Collection By Hilton
The Godfrey Detroit, Curio Collection By Hilton
4 out of 5
1401 Michigan Avenue, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Detroit. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the restaurant and the helpful staff in our reviews. ...
9/10 Wonderful! (1,553 reviews)
"Beautiful with great service"

Reviewed on Jun 30, 2025

The Godfrey Detroit, Curio Collection By Hilton
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
3 out of 5
30847 Flynn Drive, Romulus, MI
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Romulus. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.2/10 Very Good! (2,162 reviews)
"Proximity to DTW"

Reviewed on Jul 6, 2025

La Quinta Inn & Suites by Wyndham Detroit Metro Airport
Sheraton Detroit Metro Airport
Sheraton Detroit Metro Airport
3.5 out of 5
8000 Merriman Rd, Romulus, MI
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Romulus. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,002 reviews)
"They have a good service and it was a close anywhere I wanna go"

Reviewed on Jul 4, 2025

Sheraton Detroit Metro Airport
Radisson Hotel Detroit Metro Airport
Radisson Hotel Detroit Metro Airport
3 out of 5
8800 Wickham Rd, Romulus, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Romulus. Enjoy free WiFi, free parking, and a free airport shuttle. Popular attractions Gateway Golf Club and ...
7.2/10 Good! (1,004 reviews)
"For our needs, a very early flight out and a very accessible shuttle, the Radisson was perfect. The beds were very comfortable. The evening clerk was just ok in friendliness and welcoming. The morning clerk was very friendly, greeting us and wishing us a good trip. I needed a band aid and was disappointed ..."

Reviewed on Jun 28, 2025

Radisson Hotel Detroit Metro Airport
DoubleTree Suites by Hilton Hotel Detroit Downtown - Fort Shelby
DoubleTree Suites by Hilton Hotel Detroit Downtown - Fort Shelby
4 out of 5
525 West Lafayette Blvd, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star luxury hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,000 reviews)
"Excellent spot, clean and friendly."

Reviewed on Jul 1, 2025

DoubleTree Suites by Hilton Hotel Detroit Downtown - Fort Shelby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical Center

Detroit is a city that has a lot going on, but you have your sights set on Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Detroit so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $74
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.