Hotels Near
Five Points South

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Featured Five Points South Hotels

Residence Inn by Marriott Birmingham Downtown at UAB

Residence Inn by Marriott Birmingham Downtown at UAB

3 out of 5
821 20th Street S, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Birmingham. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,009 reviews)
"The staff so friendly and amicable. I would love to come back and stay at this hotel!!"

Reviewed on Jul 14, 2025

Residence Inn by Marriott Birmingham Downtown at UAB
Homewood Suites by Hilton Birmingham Downtown Near UAB

Homewood Suites by Hilton Birmingham Downtown Near UAB

3 out of 5
1016 20th Street, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Birmingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
"The pool was cloudy and was so full of chlorine we had to leave, but the room and the staff were good."

Reviewed on Jul 13, 2025

Homewood Suites by Hilton Birmingham Downtown Near UAB
Hilton Garden Inn Downtown Birmingham

Hilton Garden Inn Downtown Birmingham

3 out of 5
250 18th Street South, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Birmingham. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (784 reviews)
"Great localization, near hospitals and security."

Reviewed on Jul 9, 2025

Hilton Garden Inn Downtown Birmingham
Hilton Birmingham Downtown at UAB

Hilton Birmingham Downtown at UAB

4 out of 5
808 20th Street S, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Birmingham. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,006 reviews)
"My room needed some attention with the shower curtain"

Reviewed on Jul 6, 2025

Hilton Birmingham Downtown at UAB
The Painted Lady

The Painted Lady

2 out of 5
2143 2nd Ave S, Birmingham, AL
Stay at this hotel in Birmingham. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions The Summit and Heaviest Corner on Earth ...
9.6/10 Exceptional! (31 reviews)
"I recently stayed at the Painted Lady Hotel and really loved it. The staff were super friendly, the location was perfect for getting around, and my room was cozy, modern, and super comfortable."

Reviewed on Jul 1, 2025

The Painted Lady
Hotel Indigo Birmingham Five Points S - UAB by IHG

Hotel Indigo Birmingham Five Points S - UAB by IHG

4 out of 5
1023 20th Street South, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Birmingham. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our ...
7.4/10 Good! (1,001 reviews)
"Location was great. There wasn’t a refrigerator or microwave as advertised in the room and staying for 4 days made it hard to keep food. I had to eat out way more than I anticipated. Otherwise everything else was great."

Reviewed on Jul 10, 2025

Hotel Indigo Birmingham Five Points S - UAB by IHG
Hassinger Daniels Guest House

Hassinger Daniels Guest House

3.5 out of 5
2028 Highland Avenue South, Birmingham, AL
Stay at this 3.5-star guesthouse in Birmingham. Enjoy free parking, daily housekeeping, and a garden. Popular attractions The Summit and Alabama Museum of Health ...
9.2/10 Wonderful! (818 reviews)
"This was our fourth stay at this charming, historic property--the first with the new owners. While some of the property could use a glow-up with new paint and paper, the basics are still there- it's comfortable, charming and clean. They no longer offer the complimentary breakfast, which was nice, ..."

Reviewed on Jul 14, 2025

Hassinger Daniels Guest House
Courtyard by Marriott Birmingham Downtown at UAB

Courtyard by Marriott Birmingham Downtown at UAB

3 out of 5
1820 5th Avenue South, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Birmingham. Enjoy breakfast (surcharge), a 24-hour health club, and a 24-hour front desk. Our guests praise the ...
8.6/10 Excellent! (759 reviews)
"Friendly staff. Clean room. Good food service."

Reviewed on Jul 14, 2025

Courtyard by Marriott Birmingham Downtown at UAB
SpringHill Suites Birmingham Downtown at UAB

SpringHill Suites Birmingham Downtown at UAB

3 out of 5
2024 4th Avenue South, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Birmingham. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (1,004 reviews)
"Check in was easy and the property was very nice. The rooms are very clean and spacious. I was traveling with my husband and son. We were meeting up with my other son, his wife, and their toddler. The front desk was accommodating to place us in rooms that are next door to each other. We were close ..."

Reviewed on Jul 13, 2025

SpringHill Suites Birmingham Downtown at UAB
Tree House

Tree House

3 out of 5
1309 19th St S, Birmingham, AL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly guesthouse in Birmingham. Enjoy free WiFi, free parking, and in-room massages. Popular attractions The Summit and Vulcan ...
9.6/10 Exceptional! (68 reviews)
"We loved the house as well as the other guests. It is hard to categorized the place. I'm leaning towards hostel/ airbnb. We were assigned to the earth room, which was wonderful and relaxing, and we loved the note and details. Our favorite area was outside on the veranda (front porch). We took a midday ..."

Reviewed on Jun 10, 2025

Tree House
Holiday Inn Birmingham-Airport by IHG

Holiday Inn Birmingham-Airport by IHG

3 out of 5
5000 Richard Arrington Jr Blvd N, Birmingham, AL
Fully refundable
Stay at this 3-star business-friendly hotel in Birmingham. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the restaurant and ...
7.8/10 Good! (2,281 reviews)
"I wasn’t crazy about the surrounding area; however, the hotel was clean. My husband and I ate dinner at the hotel. Ordered the pizza, and it was delicious!"

Reviewed on Jul 12, 2025

Holiday Inn Birmingham-Airport by IHG
Hyatt Regency Birmingham-The Wynfrey Hotel

Hyatt Regency Birmingham-The Wynfrey Hotel

4 out of 5
1000 Riverchase Galleria, Hoover, Birmingham, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Birmingham. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,155 reviews)
"Average. Good stay"

Reviewed on Jul 7, 2025

Hyatt Regency Birmingham-The Wynfrey Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Five Points South

Birmingham is a city that has a lot going on, but you have your sights set on Five Points South. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Five Points South has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Five Points South hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Birmingham so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Five Points South underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Five Points South city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Five Points South cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Five Points South at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $91
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Five Points South hotel you want, book it, and never look back. Because your great escape is ahead of you.