Hotels Near
East End

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Featured East End Hotels

Sanibel Inn

Sanibel Inn

3 out of 5
937 East Gulf Drive Sanibel FL
Fully refundableReserve now, pay when you stay
Book a stay at this beach hotel in Sanibel. Enjoy a private beach, a 24-hour front desk, and daily housekeeping. Popular attractions Key West Express and Sanibel ...
9/10 Wonderful! (1,000 reviews)
Very nice hotel/resort. Clean, quiet, nice pool, attentive staff. Love the screened in balcony.

Reviewed on Dec 3, 2025

Sanibel Inn
Tarpon Tale Inn

Tarpon Tale Inn

3 out of 5
367 Periwinkle Way Sanibel FL
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and free bicycles on site. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (392 reviews)
Super cute and clean spot with bars and restaurants nearby.

Reviewed on Nov 17, 2025

Tarpon Tale Inn
Sunshine Island Inn

Sunshine Island Inn

2.5 out of 5
642 East Gulf Drive Sanibel FL
Stay at this motel in Sanibel. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Key West Express and Sanibel Island Southern Beach ...
8.8/10 Excellent! (289 reviews)
Great location and facility. Renovated so nice with a great pool. Easy beach access with chairs and umbrellas to use. Perfect place to stay!

Reviewed on Nov 22, 2025

Sunshine Island Inn
Seahorse Cottages on Sanibel - Adults Only

Seahorse Cottages on Sanibel - Adults Only

3 out of 5
1223 Buttonwood Lane Sanibel FL
Stay at this cottage in Sanibel. Enjoy free WiFi, free parking, and free bicycles on site. Popular attractions Key West Express and Sanibel Island Southern Beach ...
It is easy to get to the beach. Owners also provide a private laundry and bikes for people to ride, as well as beach equipment.

Reviewed on Jul 18, 2021

Seahorse Cottages on Sanibel - Adults Only
Lighthouse Resort and Club

Lighthouse Resort and Club

2 out of 5
210 Periwinkle Way Sanibel FL
Stay at this resort in Sanibel. Enjoy free WiFi, a beach locale, and laundry facilities. Popular attractions Key West Express and Sanibel Island Southern Beach ...
Lighthouse Resort and Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East End

Sanibel is a city that has a lot going on, but you have your sights set on East End. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East End has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East End hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Sanibel so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East End underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the East End city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East End cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in East End at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $177
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the East End hotel you want, book it, and never look back. Because your great escape is ahead of you.