Hotels Near
Medical District

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Featured Medical District Hotels

La Quinta Inn by Wyndham Huntsville Research Park

La Quinta Inn by Wyndham Huntsville Research Park

3 out of 5
4870 University Dr NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (246 reviews)
Yes

Reviewed on Dec 2, 2025

La Quinta Inn by Wyndham Huntsville Research Park
The Westin Huntsville

The Westin Huntsville

4 out of 5
6800 Governors Dr W Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (1,001 reviews)
Room clean, wife happy! The hotel doesn't disappoint. Amenities are what we need. It is located with shopping within walking distance as well as driving to areas we do need in a short time frame.

Reviewed on Dec 3, 2025

The Westin Huntsville
Everhome Suites Huntsville - Research Park

Everhome Suites Huntsville - Research Park

2.5 out of 5
5581 Holmes Avenue Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a fitness center. Popular attractions US Space and Rocket Center ...
8.4/10 Very Good! (202 reviews)
Room was spotless, staff was great and friendly! My family and it will recommend this hotel suite everytime is visit Huntsville, AL.

Reviewed on Dec 1, 2025

Everhome Suites Huntsville - Research Park
WaterWalk Extended Stay by Wyndham Huntsville

WaterWalk Extended Stay by Wyndham Huntsville

2.5 out of 5
1550 Perimeter Pkwy Huntsville AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Huntsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.4/10 Exceptional! (505 reviews)
EXCELLENT

Reviewed on Dec 1, 2025

WaterWalk Extended Stay by Wyndham Huntsville
Embassy Suites by Hilton Huntsville

Embassy Suites by Hilton Huntsville

3.5 out of 5
800 Monroe Street Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Huntsville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,015 reviews)
The hotel was nice and comfortable and VERY dog friendly.

Reviewed on Nov 28, 2025

Embassy Suites by Hilton Huntsville
Best Western Plus Madison-Huntsville Hotel

Best Western Plus Madison-Huntsville Hotel

3 out of 5
9035 Madison Boulevard Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,000 reviews)
Staff

Reviewed on Nov 30, 2025

Best Western Plus Madison-Huntsville Hotel
Sonesta Simply Suites Huntsville Research Park

Sonesta Simply Suites Huntsville Research Park

2 out of 5
201 Exchange Place Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (815 reviews)
Best place to stay in Huntsville

Reviewed on Nov 26, 2025

Sonesta Simply Suites Huntsville Research Park
Drury Inn & Suites Huntsville at the Space & Rocket Center

Drury Inn & Suites Huntsville at the Space & Rocket Center

3 out of 5
93 Wynn Drive NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,000 reviews)
Friendly staff great customer service

Reviewed on Dec 1, 2025

Drury Inn & Suites Huntsville at the Space & Rocket Center
Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone

3 out of 5
6860 Governors West NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
There were no USB plugs in rooms only in lobby. This was very inconvenient for us. Beds were just a little to firm. Comfortable but to firm for several of us in the room. Pillows went flat as soon as you layed your head on it. Pillows need a little more firmness/thickness.

Reviewed on Dec 4, 2025

Hyatt Place Huntsville/ Research Park/ Redstone
La Quinta Inn & Suites by Wyndham Huntsville Airport Madison

La Quinta Inn & Suites by Wyndham Huntsville Airport Madison

3 out of 5
105 Westchester Drive Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
Nice and clean. Good job

Reviewed on Nov 27, 2025

La Quinta Inn & Suites by Wyndham Huntsville Airport Madison
Hampton Inn & Suites Huntsville Downtown

Hampton Inn & Suites Huntsville Downtown

2.5 out of 5
313 Clinton Avenue W Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
9.2/10 Wonderful! (470 reviews)
Staff was excellent.

Reviewed on Dec 3, 2025

Hampton Inn & Suites Huntsville Downtown
stayAPT Suites Madison-Greenbrier

stayAPT Suites Madison-Greenbrier

4 out of 5
26800 Success Dr SW Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly aparthotel in Madison. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Wheeler National ...
9.4/10 Exceptional! (234 reviews)
Easy check in, cute courtyard area, huge space!

Reviewed on Nov 29, 2025

stayAPT Suites Madison-Greenbrier
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Huntsville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Huntsville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $72
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.