Hotels Near
Medical District

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Featured Medical District Hotels

La Quinta Inn by Wyndham Huntsville Research Park

La Quinta Inn by Wyndham Huntsville Research Park

3 out of 5
4870 University Dr NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (372 reviews)
Clean and comfortable. Outside doors.

Reviewed on Mar 7, 2026

La Quinta Inn by Wyndham Huntsville Research Park
Sonesta Simply Suites Huntsville Research Park

Sonesta Simply Suites Huntsville Research Park

2 out of 5
201 Exchange Place Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (865 reviews)
Didn’t feel safe. Loud argument in another room that went on for at least 30 minutes.

Reviewed on Mar 6, 2026

Sonesta Simply Suites Huntsville Research Park
The Westin Huntsville

The Westin Huntsville

4 out of 5
6800 Governors Dr W Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
Tv didn’t work and toilet was stopped up.

Reviewed on Feb 22, 2026

The Westin Huntsville
Anthem House Huntsville MidCity, powered by Placemakr

Anthem House Huntsville MidCity, powered by Placemakr

4 out of 5
945 NW Mid City Drive Huntsville AL
Fully refundableReserve now, pay when you stay
Stay at this apartment in Huntsville. Enjoy free WiFi, free valet parking, and a 24-hour fitness center. Popular attractions US Space and Rocket Center and Von ...
9.2/10 Wonderful! (62 reviews)
Great location. Very quiet and convenient. Contactless chedk in onlu applies if you sont se

Reviewed on Mar 7, 2026

Anthem House Huntsville MidCity, powered by Placemakr
Drury Inn & Suites Huntsville at the Space & Rocket Center

Drury Inn & Suites Huntsville at the Space & Rocket Center

3 out of 5
93 Wynn Drive NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,004 reviews)
Clean room, room available a bit early for check-in prior to normal check-in time. Friendly staff and easy check-in and out. Breakfast was fresh and hot, with a good selection of options. Popcorn in the afternoons and the Coke machine were great perks!

Reviewed on Mar 8, 2026

Drury Inn & Suites Huntsville at the Space & Rocket Center
Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone

3 out of 5
6860 Governors West NW Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
The staff I would say was average and below. The hotel was super nice and clean. But the hotel staff behind the desk could have given better costumer support. Example 1, I had booked two rooms together online. After checking in, we noticed the rooms were on two separate floors. So we went back up ...

Reviewed on Feb 24, 2026

Hyatt Place Huntsville/ Research Park/ Redstone
Embassy Suites by Hilton Huntsville

Embassy Suites by Hilton Huntsville

3.5 out of 5
800 Monroe Street Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Huntsville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,013 reviews)
Thanks

Reviewed on Mar 6, 2026

Embassy Suites by Hilton Huntsville
Best Western Plus Madison-Huntsville Hotel

Best Western Plus Madison-Huntsville Hotel

3 out of 5
9035 Madison Boulevard Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,007 reviews)
Ok

Reviewed on Mar 6, 2026

Best Western Plus Madison-Huntsville Hotel
Everhome Suites Huntsville - Research Park

Everhome Suites Huntsville - Research Park

2.5 out of 5
5581 Holmes Avenue Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, free parking, and a fitness center. Popular attractions US Space and Rocket Center ...
8.4/10 Very Good! (227 reviews)
Very clean and modern room. Shower height was perfect. I’m 6’5”. It’s not very often I go to a hotel that has a shower that fits. I appreciated that.

Reviewed on Mar 8, 2026

Everhome Suites Huntsville - Research Park
Hampton Inn Madison Huntsville Airport

Hampton Inn Madison Huntsville Airport

2.5 out of 5
9225 Madison Blvd Madison AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Madison. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (923 reviews)
Todo estuvo excelente! Me encanto este hotel, las instalaciones renovadas, limpieza. La atención del personal muy amigable. El Desayuno muy bueno. Lo recomiendo 100% le doy 10/10.

Reviewed on Mar 7, 2026

Hampton Inn Madison Huntsville Airport
106 Jefferson Huntsville, Curio Collection by Hilton

106 Jefferson Huntsville, Curio Collection by Hilton

4 out of 5
106 Jefferson Street Huntsville AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Huntsville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (369 reviews)
The room was very clean and the customer service was outstanding!

Reviewed on Mar 2, 2026

106 Jefferson Huntsville, Curio Collection by Hilton
Home2 Suites by Hilton Huntsville/Research Park Area, AL

Home2 Suites by Hilton Huntsville/Research Park Area, AL

3 out of 5
7010 Cabela Drive Huntsville AL
Stay at this hotel in Huntsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (565 reviews)
The staff was phenomenal 👏

Reviewed on Feb 21, 2026

Home2 Suites by Hilton Huntsville/Research Park Area, AL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical District

Huntsville is a city that has a lot going on, but you have your sights set on Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Huntsville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $80
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.