Hotels Near
Little Rock Medical District

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Featured Little Rock Medical District Hotels

Four Points by Sheraton Little Rock Midtown

Four Points by Sheraton Little Rock Midtown

3.5 out of 5
925 S University Ave, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
7.8/10 Good! (805 reviews)
It was nice loved the upstairs and down wished I stayed longer

Reviewed on Oct 19, 2025

Four Points by Sheraton Little Rock Midtown
Guest Inn & Suites - Midtown Medical Center

Guest Inn & Suites - Midtown Medical Center

3 out of 5
301 S. University Ave., Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (845 reviews)
Rate was good for area. Nothing fancy, just comfortable, except for the bed. It was too soft and leaned down at the head.

Reviewed on Oct 28, 2025

Guest Inn & Suites - Midtown Medical Center
Days Inn by Wyndham Little Rock/Medical Center

Days Inn by Wyndham Little Rock/Medical Center

2.5 out of 5
901 Fair Park Blvd, Little Rock, AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Little ...
6/10 (1,000 reviews)
It was near the hospital.

Reviewed on Oct 22, 2025

Days Inn by Wyndham Little Rock/Medical Center
Staybridge Suites Little Rock - Medical Center by IHG

Staybridge Suites Little Rock - Medical Center by IHG

3 out of 5
1020 S University Ave, Little Rock, AR
Fully refundable
Stay at this 3-star business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,001 reviews)
Great gym. Had very small kitchen in room.

Reviewed on Oct 6, 2025

Staybridge Suites Little Rock - Medical Center by IHG
Home2 Suites By Hilton Little Rock Midtown/Medical Center

Home2 Suites By Hilton Little Rock Midtown/Medical Center

3 out of 5
6300 District Ave, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Simmons Bank Arena and Park Plaza Mall are located ...
9.4/10 Exceptional! (68 reviews)
Enjoyed the quiet and cleanliness

Reviewed on Nov 2, 2025

Home2 Suites By Hilton Little Rock Midtown/Medical Center
Garden Inn and Suites Little Rock

Garden Inn and Suites Little Rock

2 out of 5
3801 W. 8th St., Little Rock, AR
Fully refundable
Stay at this motel in Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (619 reviews)
The hotel is a little old but Room was good and staff was very nice.

Reviewed on Oct 29, 2025

Garden Inn and Suites Little Rock
Spark by Hilton Little Rock West

Spark by Hilton Little Rock West

3 out of 5
9 Crossings Court, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,092 reviews)
Very clean and quiet with good staff but breakfast is just some carbs nothing substantial or warm.

Reviewed on Nov 3, 2025

Spark by Hilton Little Rock West
Wyndham Riverfront Little Rock

Wyndham Riverfront Little Rock

3.5 out of 5
2 Riverfront Pl, North Little Rock, AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in North Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,634 reviews)
We stayed here October 27-28. We were supposed to travel with another couple, however, they had a family emergency. Wyndham and hotels.com refunded the monies for this room, even though it was less than 12 hrs to check in. The front desk on both 27 & 28 were extremely accommodating and friendly, ...

Reviewed on Oct 28, 2025

Wyndham Riverfront Little Rock
Comfort Inn & Suites Presidential - Downtown Little Rock

Comfort Inn & Suites Presidential - Downtown Little Rock

3 out of 5
707 Interstate 30, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,172 reviews)
Yes

Reviewed on Nov 2, 2025

Comfort Inn & Suites Presidential - Downtown Little Rock
Little Rock Marriott

Little Rock Marriott

4 out of 5
3 Statehouse Plaza, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Little Rock. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.8/10 Excellent! (1,003 reviews)
Very quiet and comfortable room.

Reviewed on Nov 1, 2025

Little Rock Marriott
Hampton Inn & Suites Little Rock-Downtown

Hampton Inn & Suites Little Rock-Downtown

2.5 out of 5
320 River Market Avenue, Little Rock, AR
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,005 reviews)
Clean, great area, nice staff, parking garage.

Reviewed on Nov 3, 2025

Hampton Inn & Suites Little Rock-Downtown
Embassy Suites Little Rock

Embassy Suites Little Rock

3.5 out of 5
11301 Financial Centre Pkwy, Little Rock, AR
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Little Rock. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast ...
8/10 Very Good! (1,024 reviews)
Excellent

Reviewed on Oct 29, 2025

Embassy Suites Little Rock
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Little Rock Medical District

Little Rock is a city that has a lot going on, but you have your sights set on Little Rock Medical District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Little Rock Medical District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Little Rock Medical District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Little Rock so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Little Rock Medical District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Little Rock Medical District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Little Rock Medical District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Little Rock Medical District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $57
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Little Rock Medical District hotel you want, book it, and never look back. Because your great escape is ahead of you.