Search for Cheap Deals on
Hotels in Mayflower

Choose from 743 Mayflower Hotel Deals

Wyndham Riverfront Little Rock

Wyndham Riverfront Little Rock

3.5 out of 5
2 Riverfront Pl North Little Rock AR
  • 8 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in North Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,745 reviews)
Bed is comfy

Reviewed on Mar 25, 2026

Wyndham Riverfront Little Rock
Comfort Inn & Suites Presidential - Downtown Little Rock

Comfort Inn & Suites Presidential - Downtown Little Rock

3 out of 5
707 Interstate 30 Little Rock AR
  • 10 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,445 reviews)
Very clean, pleasant staff, spacious room with comfy bed, would definitely stay here again when passing thru Little Rock

Reviewed on Mar 24, 2026

Comfort Inn & Suites Presidential - Downtown Little Rock
Little Rock Marriott

Little Rock Marriott

4 out of 5
3 Statehouse Plaza Little Rock AR
  • 8 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
9/10 Wonderful! (1,000 reviews)
Very nice!

Reviewed on Mar 23, 2026

Little Rock Marriott
Hampton Inn & Suites Little Rock-Downtown

Hampton Inn & Suites Little Rock-Downtown

2.5 out of 5
320 River Market Avenue Little Rock AR
  • 9 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,000 reviews)
Checked in late and left early. Room was clean

Reviewed on Mar 24, 2026

Hampton Inn & Suites Little Rock-Downtown
Embassy Suites Little Rock

Embassy Suites Little Rock

3.5 out of 5
11301 Financial Centre Pkwy Little Rock AR
  • 13 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast ...
8.2/10 Very Good! (1,017 reviews)
The room was super nice once I entered the room on Wednesday I didn’t come back out until breakfast Thursday morning. I wanted to stay and extra night but it was for work. Checking in and out was very fast and the clerks were extremely professional. I will be returning soon. Thank you

Reviewed on Mar 23, 2026

Embassy Suites Little Rock
Motel 6 North Little Rock, AR

Motel 6 North Little Rock, AR

2 out of 5
400 W 29th St North Little Rock AR
  • 10 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly motel in North Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff ...
7.8/10 Good! (732 reviews)
Moldy bathroom and no hot water refused to refund one of our 3 days and told us it would take a week for funds to be returned so we toughed it out do not stay here drug deals going on and strong odor of marijuana throughout the property. We always stay motel 6 but this was by far the worst in the ...

Reviewed on Mar 24, 2026

Motel 6 North Little Rock, AR
Courtyard by Marriott Little Rock West

Courtyard by Marriott Little Rock West

3 out of 5
10900 Financial Centre Pkwy Little Rock AR
  • 13 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (322 reviews)
The staff was outstanding especially the young lady at the deak and Jay at the bar, for a quick overnight, it was a greaf experience!

Reviewed on Mar 14, 2026

Courtyard by Marriott Little Rock West
Motel 6 Little Rock, AR - West

Motel 6 Little Rock, AR - West

2 out of 5
10524 W Markham St Little Rock AR
  • 12 min drive from University of Arkansas for Medical Sciences
Stay at this motel in Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.4/10 (927 reviews)
Great place to stay and budget friendly for your trip if you want somewhere cheap and comfortable to stay

Reviewed on Mar 20, 2026

Motel 6 Little Rock, AR - West
Capital Hotel

Capital Hotel

3.5 out of 5
111 W Markham St Little Rock AR
  • 8 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful ...
9.4/10 Exceptional! (586 reviews)
Wonderful hotel! Staff is so friendly!!! We loved it!! The service at this hotel is unbelievable!

Reviewed on Mar 13, 2026

Capital Hotel
DoubleTree by Hilton Little Rock

DoubleTree by Hilton Little Rock

4 out of 5
424 W Markham St Little Rock AR
  • 8 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly hotel in Little Rock. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
7.8/10 Good! (1,000 reviews)
clean

Reviewed on Mar 24, 2026

DoubleTree by Hilton Little Rock
Motel 6 Little Rock, AR - Airport

Motel 6 Little Rock, AR - Airport

2 out of 5
3200 Bankhead Drive Little Rock AR
  • 17 min drive from University of Arkansas for Medical Sciences
Book a stay at this business-friendly motel in Little Rock. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our ...
6.4/10 (1,003 reviews)
Great

Reviewed on Mar 25, 2026

Motel 6 Little Rock, AR - Airport
Hilton Garden Inn Little Rock Downtown

Hilton Garden Inn Little Rock Downtown

3 out of 5
322 Rock Street Little Rock AR
  • 9 min drive from University of Arkansas for Medical Sciences
Stay at this hotel in Little Rock. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (830 reviews)
The staff were friendly rooms were clean. I would stay there again.

Reviewed on Mar 24, 2026

Hilton Garden Inn Little Rock Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mayflower

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mayflower hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mayflower.

Choosing the right hotel in Arkansas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mayflower’s 743 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $53. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mayflower hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mayflower. No matter your reason for visiting Mayflower, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mayflower hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mayflower for as low as $53.

How many hotels are there in Mayflower?

With over 743 hotels in Mayflower, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $53.

How to find cheap car rentals in Mayflower?

Finding a cheap car rental deal in Mayflower is as easy as scoring cheap hotels in Mayflower. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.