Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Featured San Francisco 4 Star Hotels

See all 672 Properties in San Francisco
Hotel Spero

Hotel Spero

405 Taylor St, San Francisco
    4.0 out of 5.0
     
     

    Hotel Spero$149

    Hotel Spero$149
    Hyatt Regency San Francisco

    Hyatt Regency San Francisco

    5 Embarcadero Center, San Francisco
      4.0 out of 5.0
       
       

      Hyatt Regency San Francisco$166

      Hyatt Regency San Francisco$166
      Argonaut Hotel - a Noble House Hotel

      Argonaut Hotel - a Noble House Hotel

      495 Jefferson St, San Francisco
        4.5 out of 5.0
         
         

        Argonaut Hotel - a Noble House Hotel$169

        Argonaut Hotel - a Noble House Hotel$169
        Hotel Nikko San Francisco

        Hotel Nikko San Francisco

        222 Mason St, San Francisco
          4.0 out of 5.0
           
           

          Hotel Nikko San Francisco$176

          Hotel Nikko San Francisco$176
          Hilton San Francisco Airport Bayfront

          Hilton San Francisco Airport Bayfront

          600 Airport Blvd, Burlingame
            4.0 out of 5.0
             
             

            Hilton San Francisco Airport Bayfront$85

            Hilton San Francisco Airport Bayfront$85
            Pullman San Francisco Bay

            Pullman San Francisco Bay

            223 Twin Dolphin Dr, Redwood City
              4.0 out of 5.0
               
               

              Pullman San Francisco Bay$98

              Pullman San Francisco Bay$98
              Hilton San Francisco Union Square

              Hilton San Francisco Union Square

              333 O'Farrell St., San Francisco
                4.0 out of 5.0
                 
                 

                Hilton San Francisco Union Square$140

                Hilton San Francisco Union Square$140
                Grand Hyatt San Francisco Union Square

                Grand Hyatt San Francisco Union Square

                345 Stockton St, San Francisco
                  4.0 out of 5.0
                   
                   

                  Grand Hyatt San Francisco Union Square$161

                  Grand Hyatt San Francisco Union Square$161
                  San Francisco Marriott Marquis

                  San Francisco Marriott Marquis

                  780 Mission Street, San Francisco
                    4.0 out of 5.0
                     
                     

                    San Francisco Marriott Marquis$159

                    San Francisco Marriott Marquis$159
                    Hilton San Francisco Financial District

                    Hilton San Francisco Financial District

                    750 Kearny St, San Francisco
                      4.0 out of 5.0
                       
                       

                      Hilton San Francisco Financial District$84

                      Hilton San Francisco Financial District$84
                      Map

                      Recently booked San Francisco hotels

                      San Francisco Airport Marriott Waterfront
                      4.0 out of 5.0
                      Last booking: 4 minutes ago
                      Music City Hotel
                      1.5 out of 5.0
                      Last booking: 4 minutes ago
                      Palace Hotel, a Luxury Collection Hotel, San Francisco
                      5.0 out of 5.0
                      Last booking: 4 minutes ago
                      Staybridge Suites San Francisco Airport
                      3.0 out of 5.0
                      Last booking: 5 minutes ago
                      Travelodge by Wyndham San Francisco Airport North
                      2.0 out of 5.0
                      Last booking: 5 minutes ago
                      Four Seasons Hotel San Francisco
                      5.0 out of 5.0
                      Last booking: 5 minutes ago
                      Jackson Court
                      2.5 out of 5.0
                      Last booking: 6 minutes ago
                      Handlery Union Square Hotel
                      3.5 out of 5.0
                      Last booking: 7 minutes ago
                      Kensington Park Hotel
                      3.5 out of 5.0
                      Last booking: 7 minutes ago