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4 Star Hotels in Otay Mesa

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Featured 4 Star Otay Mesa Hotels

Hotel del Coronado, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 25 min drive from Cross Border Xpress
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
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Opens in a new windowHotel del Coronado, Curio Collection by Hilton
Hard Rock Hotel San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Cross Border Xpress
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
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Opens in a new windowHard Rock Hotel San Diego
DoubleTree by Hilton Hotel San Diego - Mission Valley
4 out of 5
Fully refundableReserve now, pay when you stay
  • 38 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
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Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
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Courtyard by Marriott San Diego Downtown Little Italy
4 out of 5
Fully refundable
  • 31 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
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Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Hilton San Diego Mission Valley
4 out of 5
Fully refundableReserve now, pay when you stay
  • 37 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
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Opens in a new windowHilton San Diego Mission Valley
Legacy Resort Hotel & Spa
4 out of 5
  • 37 min drive from Cross Border Xpress
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
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Opens in a new windowLegacy Resort Hotel & Spa
Wyndham San Diego Bayside
4 out of 5
Fully refundableReserve now, pay when you stay
  • 31 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
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Opens in a new windowWyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from Cross Border Xpress
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
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Opens in a new windowEmbassy Suites by Hilton San Diego Bay Downtown
Lafayette Hotel & Club
4 out of 5
Fully refundableReserve now, pay when you stay
  • 36 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
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Opens in a new windowLafayette Hotel & Club
Sheraton Mission Valley San Diego Hotel
4 out of 5
  • 37 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
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Opens in a new windowSheraton Mission Valley San Diego Hotel
The Westin San Diego Bayview
4 out of 5
Fully refundableReserve now, pay when you stay
  • 30 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
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Opens in a new windowThe Westin San Diego Bayview
Manchester Grand Hyatt San Diego
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Cross Border Xpress
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
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Opens in a new windowManchester Grand Hyatt San Diego
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.