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Featured Otay Mesa Historic Hotels
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
Fully refundable
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Otay Mesa
- Hotels with a Pool in Otay Mesa
- Hotels with Free Parking in Otay Mesa
- Beach Hotels in Otay Mesa
- Family Hotels in Otay Mesa
- Winery Hotels in Otay Mesa
- Hotels with Hot Tubs in Otay Mesa
- Casinos in Otay Mesa
- Resorts & Hotels with Spas in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Luxury Hotels in Otay Mesa
Top Points of Interests in Otay Mesa
- Hotels near Cross Border Xpress
- Hotels near San Diego Zoo
- Hotels near Mission Bay
- Hotels near San Diego Convention Center
- Hotels near San Ysidro Border Crossing
- Hotels near Petco Park
- Hotels near Mission Beach
- Hotels near Balboa Park
- Hotels near Hotel Circle
- Hotels near Naval Base San Diego
- Hotels near San Diego State University
- Hotels near Port of San Diego
- Hotels near USS Midway Museum
- Hotels near Hotel del Coronado
- Hotels near Coronado Beach
- Hotels near University of San Diego
- Hotels near Naval Base Coronado
- Hotels near Seaport Village
- Hotels near Marine Corps Recruit Depot
- Hotels near Las Americas Premium Outlets
Cities near Otay Mesa
- San Diego Hotels (15.34 mi)
- Chula Vista Hotels (8.51 mi)
- Coronado Hotels (14.99 mi)
- Playas de Rosarito Hotels (21.71 mi)
- Rosarito Hotels (14.31 mi)
- Coronado Island Hotels (16.04 mi)
- El Cajon Hotels (16.26 mi)
- Southern California Hotels (91.04 mi)
- National City Hotels (10.98 mi)
- La Mesa Hotels (14.67 mi)
- Imperial Beach Hotels (8.3 mi)
- San Ysidro Hotels (4.08 mi)
- Alpine Hotels (22.51 mi)
- Tecate Hotels (19.72 mi)
- Santee Hotels (19.26 mi)
- Spring Valley Hotels (12.88 mi)
Car Rentals Near Otay Mesa
- Car rentals in San Diego
- Car rentals in Chula Vista
- Car rentals in Coronado
- Car rentals in Playas de Rosarito
- Car rentals in Rosarito
- Car rentals in Coronado Island
- Car rentals in El Cajon
- Car rentals in Southern California
- Car rentals in National City
- Car rentals in La Mesa
- Car rentals in Imperial Beach
- Car rentals in San Ysidro
- Car rentals in Alpine
- Car rentals in Tecate
- Car rentals in Santee
- Car rentals in Spring Valley
Top Booked Hotels in Otay Mesa
- Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
- Handlery Hotel
- Wyndham San Diego Bayside
- Manchester Grand Hyatt San Diego
- Marriott Marquis San Diego Marina
- The Dana on Mission Bay
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- The Dextro Hotel, BW Premier Collection
- The Little Italy Hotel Downtown San Diego
- Bay Club Hotel & Marina
- Hilton San Diego Bayfront
- Hampton Inn San Diego/Mission Valley
- Hotel del Coronado, Curio Collection by Hilton
- Alma San Diego Downtown, a Tribute Portfolio Hotel
- Kings Inn San Diego
- Sheraton San Diego Resort