Hotels Near
Guadalupe District

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Featured Guadalupe District Hotels

Guadalupe Inn
Guadalupe Inn
2 out of 5
604 Agua Fria St., Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santa Fe. Enjoy free WiFi, parking (surcharge), and a business center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (998 reviews)
Fab , quaint stay in central Santa Fe.
"Excellent stay . Walking distance to all the main central bars , restaurants and museums on offer in Santa Fe. Quaint slightly oldie worldly hotel well worth a stay. Alan at the reception was super warm and friendly and also helpful with guidance and tourism advice. I had the pleasure of meeting ..."

Reviewed on Jun 16, 2025

Guadalupe Inn
The Sage Hotel
The Sage Hotel
3 out of 5
725 Cerrillos Rd, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service, and a 24-hour fitness center. Our guests praise the breakfast and ...
7.8/10 Good! (1,746 reviews)
"We love the Sage for its friendly and relaxed staff, the well kept little pool area, and the ability to walk to the rail yards and close grocery stores. The rooms are perfectly comfortable."

Reviewed on Jun 28, 2025

The Sage Hotel
La Fonda on the Plaza
La Fonda on the Plaza
4 out of 5
100 E San Francisco St, Santa Fe, NM
Book a stay at this historic hotel in Santa Fe. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ...
9.2/10 Wonderful! (1,004 reviews)
"Amazing place to stay in Santa Fe!"

Reviewed on Jun 29, 2025

La Fonda on the Plaza
Hotel Santa Fe
Hotel Santa Fe
4 out of 5
1501 Paseo De Peralta, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Santa Fe. Enjoy an outdoor pool, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the bar ...
9.2/10 Wonderful! (1,007 reviews)
"Nice hotel and staff. Hotel has signs of wear and needs a little TLC."

Reviewed on Jun 30, 2025

Hotel Santa Fe
Piñon Court By La Fonda
Piñon Court By La Fonda
3 out of 5
201 Montezuma Ave, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Santa Fe. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast ...
9.2/10 Wonderful! (1,013 reviews)
"Had a good experience. There are no elevators and that could be tough for some, but if your ok with potentially having to go upstairs the room was very nice. Slightly expensive with fees and taxes but the free breakfast is better than most hotels. Easy to walk to many restaurants. If you need ice ..."

Reviewed on Jun 27, 2025

Piñon Court By La Fonda
The Mystic Santa Fe
The Mystic Santa Fe
2 out of 5
2810 Cerrillos Road, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this motel in Santa Fe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,168 reviews)
"The Mystic has a retro charm, and a comfortable bar in the evening."

Reviewed on Jun 30, 2025

The Mystic Santa Fe
Eldorado Hotel & Spa
Eldorado Hotel & Spa
4 out of 5
309 W San Francisco Street, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Santa Fe. Enjoy a full-service spa, 2 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,004 reviews)
"Beautiful place to stay. friendly staff , clean , great food and drinks. I definitely will be going back for another visit."

Reviewed on Jun 29, 2025

Eldorado Hotel & Spa
Coyote South
Coyote South
3.5 out of 5
3358 Cerrillos Rd, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Santa Fe. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the ...
8.2/10 Very Good! (2,429 reviews)
"Great location and seamless stay"

Reviewed on Jun 29, 2025

Coyote South
Inn and Spa at Loretto
Inn and Spa at Loretto
4 out of 5
211 Old Santa Fe Trail, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santa Fe. Enjoy breakfast (surcharge), a fitness center, and onsite spa services. Our guests praise the restaurant ...
9/10 Wonderful! (1,009 reviews)
"Wow! So beautiful. Our room was right above the chapel, so great view"

Reviewed on Jun 30, 2025

Inn and Spa at Loretto
Hilton Santa Fe Buffalo Thunder
Hilton Santa Fe Buffalo Thunder
4 out of 5
20 Buffalo Thunder Trl, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa resort in Santa Fe. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,004 reviews)
"Friendly, clean and nice amenities."

Reviewed on Jun 21, 2025

Hilton Santa Fe Buffalo Thunder
El Sendero Inn, Ascend Hotel Collection
El Sendero Inn, Ascend Hotel Collection
2.5 out of 5
311 Old Santa Fe Trail, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santa Fe. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,449 reviews)
Wonderful!!
"It was excellent!! Very friendly front desk staff!!"

Reviewed on Jun 28, 2025

El Sendero Inn, Ascend Hotel Collection
Drury Plaza Hotel in Santa Fe
Drury Plaza Hotel in Santa Fe
3.5 out of 5
828 Paseo de Peralta, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Santa Fe. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,264 reviews)
"Great location, nice hotel, the room had no view and felt like a cave however, so that was disappointing."

Reviewed on Jun 29, 2025

Drury Plaza Hotel in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Guadalupe District

Santa Fe is a city that has a lot going on, but you have your sights set on Guadalupe District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Guadalupe District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Guadalupe District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Santa Fe so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Guadalupe District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Guadalupe District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Guadalupe District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Guadalupe District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Guadalupe District hotel you want, book it, and never look back. Because your great escape is ahead of you.