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Hotels in Santee

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Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
  • 10 min drive from Mission Trails Regional Park
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,497 reviews)
Beautiful location, but our stay was disappointing due to several issues. We found a large bug in the room, the bathroom door got stuck and locked my son inside (maintenance said it had happened before), and the AC unit smelled strongly like urine when turned on. The shower also had visible buildup. ...

Reviewed on Apr 1, 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
  • 11 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.8/10 Good! (3,345 reviews)
Clean, comfortable

Reviewed on Apr 1, 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
  • 19 min drive from Mission Trails Regional Park
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,465 reviews)
Clean room, helpful enthusiastic staff, and a nice hotel to stay at overall. The location is prime if you’re a baseball fan or going to an event at the convention center because the hotel is just across the street.

Reviewed on Apr 1, 2026

Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
  • 11 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,364 reviews)
Love the pool

Reviewed on Mar 31, 2026

Handlery Hotel
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
  • 17 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (1,292 reviews)
Nice hotel

Reviewed on Apr 1, 2026

The DEXTRO Little Italy, BW Premier Collection
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
  • 11 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (2,579 reviews)
staff cleans daily if needed. nice front desk staff

Reviewed on Mar 31, 2026

Days Inn by Wyndham San Diego Hotel Circle
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
  • 19 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,870 reviews)
Great room and friendly staff

Reviewed on Apr 1, 2026

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
  • 17 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,104 reviews)
We went as a family of 4. Stayed 3 nights to check out the zoo and USS Midway. The elevator with the glass dome was a huge hit for the kids. We hit the pool every day. The onsite restaurants and gift shop had all the important things! Perfect for a home away from home for a few days.

Reviewed on Apr 1, 2026

Wyndham San Diego Bayside
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
  • 11 min drive from Mission Trails Regional Park
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,218 reviews)
Great location very close (walking distance) to Sea World. Nice pools, reasonably priced drinks and a nice restaurant (the Firefly)

Reviewed on Mar 31, 2026

The Dana on Mission Bay
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
  • 16 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,405 reviews)
Overall, our family of 4’s stay was pleasant. The only thing was there was what I believe to be sewage gas backup coming out of the shower drain (room 440). Had the same experience at the Sheraton Toronto Airport, something about these older Sheraton hotels…

Reviewed on Mar 31, 2026

Sheraton San Diego Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
  • 18 min drive from Mission Trails Regional Park
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,864 reviews)
Great stay. Clean rooms. Close to everything in walking distance

Reviewed on Apr 1, 2026

The Sofia Hotel
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
  • 20 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (2,255 reviews)
Acceptable

Reviewed on Apr 1, 2026

DoubleTree by Hilton San Diego - Del Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santee

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $94. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santee hotel deals at the last minute.

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Frequently Asked Questions About Santee hotels

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How many hotels are there in Santee?

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How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.