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Hotels in Santee

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Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
  • 9 min drive from Mission Trails Regional Park
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,423 reviews)
The hotel was plenty fine, but the grounds were just dirty feeling.

Reviewed on Feb 18, 2026

Paradise Point Resort & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
  • 19 min drive from Mission Trails Regional Park
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,329 reviews)
It was great

Reviewed on Feb 18, 2026

Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
  • 17 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,078 reviews)
Everything was excellent

Reviewed on Feb 18, 2026

The DEXTRO Little Italy, BW Premier Collection
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
  • 18 min drive from Mission Trails Regional Park
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,778 reviews)
Good

Reviewed on Feb 18, 2026

The Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
  • 17 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,040 reviews)
Perfect location! Very clean and the staff were wonderful! The bay view was gorgeous.

Reviewed on Feb 18, 2026

Wyndham San Diego Bayside
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
  • 11 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (2,478 reviews)
Room was clean ,beds are good

Reviewed on Feb 17, 2026

Days Inn by Wyndham San Diego Hotel Circle
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
  • 12 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
9.2/10 Wonderful! (638 reviews)
the room smell like pets and there's no parking available

Reviewed on Feb 17, 2026

Hampton Inn & Suites by Hilton San Diego SeaWorld
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
  • 11 min drive from Mission Trails Regional Park
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,097 reviews)
Every single staff member in every single interaction was pleasant. Room and pool immaculate. Housekeeping excellent. Just about perfect.

Reviewed on Feb 18, 2026

The Dana on Mission Bay
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real San Diego CA
  • 20 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (2,072 reviews)
All great

Reviewed on Feb 18, 2026

DoubleTree by Hilton San Diego - Del Mar
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
  • 24 min drive from Mission Trails Regional Park
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,005 reviews)
Excellent weather, service and atmosphere.

Reviewed on Feb 16, 2026

Hotel del Coronado, Curio Collection by Hilton
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
  • 18 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,401 reviews)
Easy, quick check-in. Great location on Shelter Island. Morning coffee was tasty. Bar and Dining room service was first rate. Friendly staff all around. Looking forward to our next stay!

Reviewed on Feb 18, 2026

Bay Club Hotel & Marina
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
  • 11 min drive from Mission Trails Regional Park
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,442 reviews)
Everything was great, except the weather!

Reviewed on Feb 17, 2026

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santee

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Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santee?

With over 9,768 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $92.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.