Hotels NearEast Main Street
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Featured East Main Street Hotels

Grand Junction Vacation Rental w/ Fire Pit!

Grand Vista Hotel
Yvonne at the check in was very helpful. She also picked us up from the airport when we had to return our car.
Reviewed on Nov 22, 2025

La Quinta Inn & Suites by Wyndham Grand Junction
Clean, specious, great room! Very happy with our stay!
Reviewed on Nov 18, 2025

Super 8 by Wyndham Grand Junction Colorado
Check-in was quick and efficient. The housekeeping staff were attentive and efficient, as well. The location is close to many eateries and is centrally located. Overall, my stay was pleasant.
Reviewed on Nov 17, 2025

Tru by Hilton Grand Junction Downtown
clean room, friendly staff
Reviewed on Nov 17, 2025

La Quinta Inn & Suites by Wyndham Fruita
Clean room, good breakfast options, great to be able to stay with our dog.
Reviewed on Nov 18, 2025

Comfort Inn & Suites
Room was very clean. Staff is friendly and professional.
Reviewed on Nov 13, 2025

Clarion Inn Grand Junction
This place smells great!
Reviewed on Nov 16, 2025

Ramada by Wyndham Grand Junction
Plus: Nice and helpful staff, clean room, good hot breakfast, comfortable bed. Minus: Very poor soundproofing.
Reviewed on Nov 20, 2025

Comfort Inn Grand Junction I-70
Room was like new
Reviewed on Nov 20, 2025

Hampton Inn Grand Junction Downtown/Historic Main Street
Great staff
Reviewed on Nov 10, 2025

Doubletree Hotel Grand Junction
Very clean and friendly staff! Restaurant had excellent food and service!
Reviewed on Nov 15, 2025
Hotels in East Main Street
Grand Junction is a city that has a lot going on, but you have your sights set on East Main Street. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East Main Street has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East Main Street hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of Grand Junction so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East Main Street underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the East Main Street city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East Main Street cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in East Main Street at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $63
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the East Main Street hotel you want, book it, and never look back. Because your great escape is ahead of you.
Hotels by Star Rating
East Main Street Neighborhoods
Top Attractions in East Main Street
- Hotels near Colorado River (399.03 mi)
- Hotels near Colorado Mesa University (0.8 mi)
- Hotels near Colorado National Monument (8.03 mi)
- Hotels near Canyon View Park (4.19 mi)
- Hotels near Two Rivers Convention Center (0.99 mi)
- Hotels near Redlands Mesa Golf Club (3.86 mi)
- Hotels near Bananas Fun Park (2.67 mi)
- Hotels near Western Colorado Botanical Gardens (0.97 mi)
- Hotels near Gunnison River (33.89 mi)
- Hotels near Grand Junction Motor Speedway (4.07 mi)
- Hotels near Mesa County Fairgrounds (2.31 mi)
- Hotels near Grand Mesa National Forest (34.93 mi)
- Hotels near High Country Orchards (8.52 mi)
- Hotels near Western Colorado Center for the Arts (1.26 mi)
- Hotels near Colorado Welcome Center (11.56 mi)
- Hotels near Connected Lakes (2.59 mi)
- Hotels near Cross Orchards Historic Site (4.03 mi)
Cities near East Main Street
- Grand Junction Hotels (0.24 mi)
- Fruita Hotels (11.42 mi)
- Palisade Hotels (11.15 mi)
- Rocky Mountains Hotels (690.09 mi)
- Mesa Hotels (23.13 mi)
- Clifton Hotels (5.75 mi)
- Gateway Hotels (35.15 mi)
- Whitewater Hotels (21.99 mi)
- Western United States Hotels (267.72 mi)
- Loma Hotels (16.59 mi)
- Southern Rocky Mountains Hotels (91.36 mi)
- De Beque Hotels (26.64 mi)
- Glade Park Hotels (11.35 mi)
- Colorado Western Slope Hotels (56.03 mi)
- Southwest Colorado Hotels (89.18 mi)
- Northwest Colorado Hotels (84.66 mi)
- Mountain States Hotels (264.26 mi)
- Central Colorado Hotels (95.96 mi)
- Southeastern Utah - Glen Canyon National Recreation Area Hotels (103.98 mi)
- Dinosaur Diamond Prehistoric Highway Hotels (66.55 mi)
