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Hotels in South Carolina Midlands

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Choose from 3275 South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 34 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,090 reviews)
"Staff was really pleasant and nice to deal with"

Reviewed on Jun 7, 2026

Hilton Garden Inn Columbia/Harbison
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
  • 13 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,023 reviews)
"Hotel is clean and well maintained. I liked it"

Reviewed on Jun 6, 2026

Courtyard by Marriott Columbia Downtown at USC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Palmetto Performing Arts and ...
8/10 Very Good! (1,014 reviews)
"Friendly clean reasonable price"

Reviewed on Jun 5, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
  • 15 min drive from Fort Jackson
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (692 reviews)
"The Gentleman At The Front Desk Was Extremely Nice, Helpful And Friendly. The Property Was Beautiful. I Loved The Bar Aspect And The Outside Boho Feel With The Chairs. I Loved The Free Breakfast, As I Was Here For My Son's Basketball Weekend. That Was Beneficial. The Room Was Clean (And I Don't Say ..."

Reviewed on Jun 6, 2026

Tru By Hilton Columbia Downtown
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,296 reviews)
"The stay was ok. Average hotel."

Reviewed on Jun 6, 2026

Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (177 reviews)
"Very clean."

Reviewed on Jun 6, 2026

Quality Inn & Suites Florence Civic Center
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
  • 14 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,005 reviews)
"Very clean"

Reviewed on May 29, 2026

Hyatt Place Columbia/Downtown/The Vista
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 25 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,087 reviews)
"The hotel wasn’t clean like the pictures on the website. The bathrooms and showers were in port condition. There was trash in the parking lot. Only one ice machine and it was in the breakfast area. The elevator was one of the slowest I’ve ever been on. The pillows were flat and the beds were ..."

Reviewed on Jun 6, 2026

Sleep Inn Columbia
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.8/10 Good! (1,104 reviews)
"The breakfast was pretty good"

Reviewed on Jun 6, 2026

Country Inn & Suites by Radisson, Columbia, SC
Quality Inn Columbia Airport

Quality Inn Columbia Airport

2.5 out of 5
2516 Augusta Rd West Columbia SC
  • 24 min drive from Fort Jackson
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,003 reviews)
"This I enjoyed stay here.."

Reviewed on Jun 5, 2026

Quality Inn Columbia Airport
Clarion Pointe Rock Hill Near University

Clarion Pointe Rock Hill Near University

2.5 out of 5
1106 N. Anderson Road Rock Hill SC
  • 3 hours drive from Fort Jackson
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,071 reviews)
"The room was clean and modern. The staff was very accommodating. The facility was very quiet, especially considering that there was a club basketball team staying there as well."

Reviewed on Jun 5, 2026

Clarion Pointe Rock Hill Near University
 La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

3 out of 5
1538 Horseshoe Drive Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (2,008 reviews)
"Breakfast was very good."

Reviewed on Jun 4, 2026

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Carolina Midlands

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in South Carolina Midlands.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South Carolina Midlands’s 3,275 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Carolina Midlands hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Carolina Midlands. No matter your reason for visiting South Carolina Midlands, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Carolina Midlands hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South Carolina Midlands for as low as $68.

How many hotels are there in South Carolina Midlands?

With over 3,275 hotels in South Carolina Midlands, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in South Carolina Midlands?

Finding a cheap car rental deal in South Carolina Midlands is as easy as scoring cheap hotels in South Carolina Midlands. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.