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Tru By Hilton Santee
Baymont by Wyndham Santee
"This is an old property. They have tried to update, but it shows its age. It had a pool that is filled with concrete, poor caulking around the tub enclosure and it smelled vaguely of urine. This is probably because it is "pet friendly "...so not so people friendly! Breakfast was minimal..it did have ..."
Reviewed on Oct 15, 2026
Fairfield Inn & Suites by Marriott Santee
Comfort Inn & Suites Santee
Best Western Plus Santee Inn
Hampton Inn Santee-I-95
Holiday Inn Santee by IHG
"The hotel had a restaurant inside it. They refused to allow my service dog in so I went to another restaurant. I complained to the manager upon check out and she apologized about the incident. Said she was going to correct the employee and the policy."
Reviewed on Oct 14, 2026
Quality Inn & Suites Santee I-95
"would never stay there again"
Reviewed on Oct 12, 2026
Travelodge by Wyndham Santee
"Nice bed, water was very hot which is nice, and satellite TV with tons of channels."
Reviewed on Oct 10, 2026
Ramada by Wyndham Santee I-95
Red Roof Inn Santee
"Nice place. Clean & mattress was super comfy!"
Reviewed on Sep 6, 2026
Super 8 by Wyndham, Orangeburg
"The front desk gentleman was very kind and helpful. The hotel room was dirty and worn out. I paid around $95 for one night with my pet fee included. I slept well and left very early morning. I probably would stay somewhere else next time. It wasn’t awful, but it really needed a deep cleaning."
Reviewed on Oct 11, 2026
Find cheap hotels in Santee
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.
Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 353 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santee hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santee. No matter your reason for visiting Santee, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Santee hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santee for as low as $65.
How many hotels are there in Santee?
With over 353 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.
How to find cheap car rentals in Santee?
Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Hotels near Santee State Park
- Hotels near Santee Cooper Country Club
- Hotels near Santee National Golf Club
- Hotels near Congaree National Park
- Hotels near Lake Marion
- Hotels near South Carolina State University
- Hotels near Wyboo Golf Club
- Hotels near Edisto Memorial Gardens
- Hotels near Santee National Wildlife Refuge
- Hotels near St. George United Methodist Church
- Hotels near I.P. Stanback Museum & Planetarium
- Hotels near St. George Country Club
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