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Hotels in Santee

Last Minute Hot Rate® Hotel Deals in Santee

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Choose from 176 Santee Hotel Deals

Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $47 per night from Feb 19 to Feb 20
$47
per night
Feb 19 - Feb 20
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
3.4/5 (332 reviews)
"Convenient access off of I95 for our trip"

Reviewed on Feb 6, 2023

Travelodge by Wyndham Santee
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $79 per night from Feb 9 to Feb 10
$79
per night
Feb 9 - Feb 10
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the convenient parking ...
4/5 Very Good! (896 reviews)
"stayed two nites to take a break in driving to Fla.. clean,quite, and right off I95."

Reviewed on Feb 7, 2023

Baymont by Wyndham Santee
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC, 29142-8932
  • 6 min drive from Santee State Park
The price is $123 per night from Feb 19 to Feb 20
$123
per night
Feb 19 - Feb 20
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast. Our guests praise the breakfast and the restaurant in our reviews. Popular ...
4/5 Very Good! (553 reviews)
"The property was clean and organized"

Reviewed on Feb 5, 2023

Holiday Inn Santee, an IHG Hotel
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $142 per night from Feb 15 to Feb 16
$142
per night
Feb 15 - Feb 16
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
4.8/5 Exceptional! (672 reviews)
"Very nice stay. Staff very professional and friendly"

Reviewed on Feb 5, 2023

Fairfield Inn & Suites by Marriott Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $105 per night from Mar 9 to Mar 10
$105
per night
Mar 9 - Mar 10
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
4.2/5 Excellent! (1,035 reviews)
"Safe feeling, smelled good, nice people, and reasonably priced."

Reviewed on Jan 28, 2023

Best Western Plus Santee Inn
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $142 per night from Feb 15 to Feb 16
$142
per night
Feb 15 - Feb 16
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
4.7/5 Exceptional! (1,041 reviews)
Excellent stay for road trips
"Great hotel stay on I-95. The gym was well equipped for a quick workout. We really felt the southern charm from all the workers we encountered. Perfect rest stop for a road trip!"

Reviewed on Feb 7, 2023

Hampton Inn Santee-I-95
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $118 per night from Feb 15 to Feb 16
$118
per night
Feb 15 - Feb 16
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the spacious rooms in our reviews. Popular ...
3.9/5 Good! (710 reviews)
Compassion at Hotels .com
"While I was unable to stay at your hotel, I was very impressed with the compassion and understanding, when I had to cancel at the last minute due to a family emergency. Thank you!"

Reviewed on Feb 1, 2023

Comfort Inn & Suites Santee
Red Roof Inn Santee
Red Roof Inn Santee
2 out of 5
9091 Old Hwy 6, Santee, SC, 29142
  • 6 min drive from Santee State Park
The price is $69 per night from Feb 9 to Feb 10
$69
per night
Feb 9 - Feb 10
Stay at this motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the convenient parking and the clean rooms in our reviews. ...
3.1/5 (492 reviews)
"It was average for price."

Reviewed on Feb 4, 2023

Red Roof Inn Santee
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2 out of 5
9125 Old Highway 6, Santee, SC, 29142-8899
  • 7 min drive from Santee State Park
The price is $75 per night from Feb 9 to Feb 10
$75
per night
Feb 9 - Feb 10
Stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular ...
3.2/5 (346 reviews)
"good one night stay. Good value"

Reviewed on Jan 14, 2023

Super 8 by Wyndham Santee
Econo Lodge
Econo Lodge
2 out of 5
9112 Old 6 Highway, Santee, SC, 29142-8898
  • 7 min drive from Santee State Park
The price is $48 per night from Feb 22 to Feb 23
$48
per night
Feb 22 - Feb 23
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff in our reviews. ...
3.1/5 (308 reviews)
OK for an overnighter
"Hotel needs a facelift inside and out. While bed was comfortable enough overall the place felt dingy. They appeared to be working on painting inside of some rooms and hope outside will also get some attention. Person who checked us in was lacking personality."

Reviewed on Oct 28, 2022

Econo Lodge
Wyndham Vacation Resorts Lake Marion
Wyndham Vacation Resorts Lake Marion
4 out of 5
401 Bass Drive, Santee, SC, 29412
  • 6 min drive from Santee State Park
Stay at this 4-star vacation home in Santee. Enjoy free WiFi, free parking, and an in-room DVD player. Popular attractions Santee Cooper Country Club and Santee ...
4.5/5 Wonderful! (11 reviews)
"It's great to wake up to a lake and wildlife right outside the back door and balcony. Rooms are very spacious and clean."

Reviewed on Feb 1, 2021

Wyndham Vacation Resorts Lake Marion
Rodeway Inn Santee I-95
Rodeway Inn Santee I-95
2 out of 5
123 Mall Street, Santee, SC, 29142
  • 7 min drive from Santee State Park
The price is $64 per night from Mar 6 to Mar 7
$64
per night
Mar 6 - Mar 7
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
3/5 (471 reviews)
Modest but pleasing
"Just needed a place to sleep during long distance travel. This place fit the bill, easy access, clean comfortable room & bed. The AC unit was loud & tripped on & off frequently. Turned it off for better sleep."

Reviewed on Apr 24, 2022

Rodeway Inn Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Santee

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santee hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 176 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $47. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Santee hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santee. No matter your reason for visiting Santee, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santee for as low as $47.

How many hotels are there in Santee?

With over 176 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $47.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Santee now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Santee right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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