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Hotels in Santee

Check Last Minute Santee Hotel Deals

Tonight Jul 27 - Jul 28Next weekend Aug 2 - Aug 4

Choose from 232 Santee Hotel Deals

Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 out of 5
249 Britain Street, Santee, SC
  • 7 min drive from Santee State Park
The price is $83 per night from Jul 28 to Jul 29
$83
includes taxes & fees
Jul 28 - Jul 29
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the comfy rooms and the overall value ...
7.8/10 Good! (1,298 reviews)
"Top notch"

Reviewed on Jul 21, 2024

Baymont by Wyndham Santee
Tru By Hilton Santee
Tru By Hilton Santee
2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
  • 7 min drive from Santee State Park
The price is $127 per night from Aug 11 to Aug 12
$127
includes taxes & fees
Aug 11 - Aug 12
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee Outlets ...
9/10 Wonderful! (170 reviews)
"Very eclectic nice. Breakfast was good too"

Reviewed on Jul 21, 2024

Tru By Hilton Santee
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 out of 5
221 Britain St, Santee, SC
  • 7 min drive from Santee State Park
The price is $126 per night from Aug 8 to Aug 9
$126
includes taxes & fees
Aug 8 - Aug 9
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Outlets and Santee Cooper Country Club are located ...
7.8/10 Good! (865 reviews)
"Very nice facility. 5 stars in every way."

Reviewed on Jul 24, 2024

Comfort Inn & Suites Santee
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $158 per night from Aug 5 to Aug 6
$158
includes taxes & fees
Aug 5 - Aug 6
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the comfy rooms and the property condition in our reviews. ...
9.8/10 Exceptional! (1,000 reviews)
"Great and clean place, easy access to highway and most importantly the staff was very friendly and courteous. Will be stopping there again in the future."

Reviewed on Jul 19, 2024

Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $161 per night from Aug 7 to Aug 8
$161
includes taxes & fees
Aug 7 - Aug 8
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the comfy rooms and the property condition in our reviews. ...
9.4/10 Exceptional! (1,002 reviews)
"This is a great place to stay. Pet friendly with a wonderful pool and gym. The beds and pillows are so comfy with extra large rooms! The rooms are super clean and the breakfast is hot with so many choices. The nice lady that works in the breakfast area is so friendly and helpful."

Reviewed on Jul 25, 2024

Hampton Inn Santee-I-95
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5
8929 Old Number Six Highway, Santee, SC
  • 6 min drive from Santee State Park
The price is $70 per night from Aug 1 to Aug 2
$70
includes taxes & fees
Aug 1 - Aug 2
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (244 reviews)
"Just what we needed."

Reviewed on Jul 2, 2024

Quality Inn & Suites
Holiday Inn Santee, an IHG Hotel
Holiday Inn Santee, an IHG Hotel
3 out of 5
139 Bradford Blvd, Santee, SC
  • 6 min drive from Santee State Park
The price is $123 per night from Jul 29 to Jul 30
$123
includes taxes & fees
Jul 29 - Jul 30
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Santee Outlets and Santee Cooper Country ...
8/10 Very Good! (761 reviews)
Holiday inn
"My only complaint was we weren’t told about the $75 dog fee"

Reviewed on Jul 26, 2024

Holiday Inn Santee, an IHG Hotel
Travelodge by Wyndham Santee
Travelodge by Wyndham Santee
2 out of 5
9117 Old Number Six Hwy, Santee, SC
  • 7 min drive from Santee State Park
The price is $67 per night from Jul 28 to Jul 29
$67
includes taxes & fees
Jul 28 - Jul 29
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee Outlets are located ...
6.8/10 (520 reviews)
"We stayed here on the way to the Port of Charleston. Beds were comfortable but small as they are doubles and there are 4 of us. Rooms were clean. Check in was fast and easy. Parking is plentiful. There is a pool that is not in service, but we weren’t here for that. The outside is a bit messy/run ..."

Reviewed on Jul 20, 2024

Travelodge by Wyndham Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 out of 5
I 95 Exit 98, Santee, SC
  • 7 min drive from Santee State Park
The price is $127 per night from Aug 4 to Aug 5
$127
includes taxes & fees
Aug 4 - Aug 5
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
Lovely stay.
"We had a beautiful view of the golf course. It was lovely! Our remote for the TV didn't work but someone came promptly, afterthought on a weekend, too check batteries, etc."

Reviewed on Jul 14, 2024

Best Western Plus Santee Inn
Red Roof Inn Santee
Red Roof Inn Santee
2 out of 5
9091 Old Hwy 6, Santee, SC
  • 6 min drive from Santee State Park
The price is $71 per night from Jul 28 to Jul 29
$71
includes taxes & fees
Jul 28 - Jul 29
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (563 reviews)
"It was dated and needs some maintenance. Get what you pay for."

Reviewed on Jul 8, 2024

Red Roof Inn Santee
Super 8 by Wyndham Santee
Super 8 by Wyndham Santee
2 out of 5
9125 Old Highway 6, Santee, SC
  • 7 min drive from Santee State Park
The price is $83 per night from Jul 28 to Jul 29
$83
includes taxes & fees
Jul 28 - Jul 29
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions ...
6.6/10 (396 reviews)
"Very comfortable and convenient place to stay"

Reviewed on Jul 23, 2024

Super 8 by Wyndham Santee
Rodeway Inn Santee I-95
Rodeway Inn Santee I-95
2 out of 5
123 Mall Street, Santee, SC
  • 7 min drive from Santee State Park
The price is $100 per night from Jul 29 to Jul 30
$100
includes taxes & fees
Jul 29 - Jul 30
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.2/10 (501 reviews)
"The staff was exceptionally nice and accommodating. Room was appropriately priced. I will definitely stay here again in the future."

Reviewed on Jul 10, 2024

Rodeway Inn Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Santee

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santee hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 232 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $67. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Santee hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santee. No matter your reason for visiting Santee, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santee for as low as $67.

How many hotels are there in Santee?

With over 232 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Santee now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Santee right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.