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South Carolina Midlands

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South Carolina Midlands Flights as Low as $182

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Thu, Jun 18 - Tue, Jun 30
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$182 Roundtrip, found 14 hours ago
$182
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Jun 18 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 30, priced at $182 found 14 hours ago
Delta
Thu, Jun 18 - Tue, Jun 30
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$187 Roundtrip, found 14 hours ago
$187
Roundtrip
found 14 hours ago
Select Delta flight, departing Thu, Jun 18 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 30, priced at $187 found 14 hours ago
Frontier Airlines
Thu, Jun 18 - Tue, Jun 30
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$194 Roundtrip, found 14 hours ago
$194
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Thu, Jun 18 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 30, priced at $194 found 14 hours ago
Frontier Airlines
Tue, Jul 21 - Tue, Jul 28
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$203 Roundtrip, found 16 hours ago
$203
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Tue, Jul 21 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jul 28, priced at $203 found 16 hours ago
Frontier Airlines
Thu, Sep 17 - Sat, Sep 19
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$208 Roundtrip, found 1 day ago
$208
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Sep 17 from LaGuardia to Charlotte-Douglas Intl., returning Sat, Sep 19, priced at $208 found 1 day ago
Bargain Flight
Wed, Aug 19 - Tue, Sep 1
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$211 Roundtrip, found 5 hours ago
$211
Roundtrip
found 5 hours ago
Select Bargain Flight flight, departing Wed, Aug 19 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Sep 1, priced at $211 found 5 hours ago
American Airlines
Thu, Jun 18 - Tue, Jun 30
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$218 Roundtrip, found 14 hours ago
$218
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Jun 18 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 30, priced at $218 found 14 hours ago
Delta
Thu, Jun 18 - Tue, Jun 30
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$223 Roundtrip, found 14 hours ago
$223
Roundtrip
found 14 hours ago
Select Delta flight, departing Thu, Jun 18 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Jun 30, priced at $223 found 14 hours ago
Bargain Flight
Wed, Jun 3 - Wed, Jun 17
LGA
LaGuardia
CAE
Columbia Metropolitan
$248 Roundtrip, found 22 hours ago
$248
Roundtrip
found 22 hours ago
Select Bargain Flight flight, departing Wed, Jun 3 from LaGuardia to Columbia Metropolitan, returning Wed, Jun 17, priced at $248 found 22 hours ago
Bargain Flight
Fri, Jun 5 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
CAE
Columbia Metropolitan
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Jun 5 from Detroit Metropolitan Wayne County to Columbia Metropolitan, returning Sat, Jun 6, priced at $263 found 1 day ago
American Airlines
Tue, Jul 14 - Thu, Jul 30
LGA
LaGuardia
FLO
Florence Regional
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Jul 14 from LaGuardia to Florence Regional, returning Thu, Jul 30, priced at $283 found 2 hours ago
Delta
Thu, Oct 22 - Sun, Oct 25
LGA
LaGuardia
AGS
Augusta Regional
$298 Roundtrip, found 6 days ago
$298
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 22 from LaGuardia to Augusta Regional, returning Sun, Oct 25, priced at $298 found 6 days ago
JetBlue Airways
Wed, Aug 19 - Tue, Sep 1
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$353 Roundtrip, found 5 hours ago
$353
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Wed, Aug 19 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Sep 1, priced at $353 found 5 hours ago
Delta
Wed, May 27 - Tue, Jun 9
DTW
Detroit Metropolitan Wayne County
AGS
Augusta Regional
$382 Roundtrip, found 6 hours ago
$382
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, May 27 from Detroit Metropolitan Wayne County to Augusta Regional, returning Tue, Jun 9, priced at $382 found 6 hours ago
American Airlines
Wed, May 27 - Sat, May 30
CMH
John Glenn Columbus Intl.
FLO
Florence Regional
$511 Roundtrip, found 23 hours ago
$511
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Wed, May 27 from John Glenn Columbus Intl. to Florence Regional, returning Sat, May 30, priced at $511 found 23 hours ago
American Airlines
Thu, Jul 23 - Fri, Jul 31
DTW
Detroit Metropolitan Wayne County
FLO
Florence Regional
$568 Roundtrip, found 23 hours ago
$568
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Thu, Jul 23 from Detroit Metropolitan Wayne County to Florence Regional, returning Fri, Jul 31, priced at $568 found 23 hours ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $182, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $182 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$230

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
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Hilton Garden Inn Columbia/Harbison
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,677 reviews)
"All good and the best value at Florence. Only downside is the walkways are missing paint so don’t look nice."

Reviewed on May 25, 2026

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Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (155 reviews)
"Great spot to stay for a quick over night when traveling!"

Reviewed on May 25, 2026

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Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,278 reviews)
"Calidad"

Reviewed on May 25, 2026

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Park Inn by Radisson Florence, SC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
8/10 Very Good! (1,004 reviews)
"My stay was very comfortable and I was able to relax and enjoy myself. Everyone was very helpful and the property is very clean. Rooms are very nice and clean. Food was good . The eggs could be scrambled instead of frozen round eggs. But I will be visiting again😊"

Reviewed on May 24, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,086 reviews)
"Loves the property"

Reviewed on May 24, 2026

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Sleep Inn Columbia
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (671 reviews)
"Excellent stay!"

Reviewed on May 25, 2026

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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,013 reviews)
"Unfortunately our room was sub par as far as cleanliness. I told the front desk after checking in that the toilet seemed dirty with some type of residue on the base and floor. Although they apologized nothing was done . The next morning checking out I mentioned it again and said no one followed thru ..."

Reviewed on May 24, 2026

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Courtyard by Marriott Columbia Downtown at USC
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.6/10 (1,002 reviews)
"Clean room. Hotel is doing an amazing job with renovations and upgrades as time moves on."

Reviewed on May 25, 2026

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Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,008 reviews)
"Amazing!!! I would definately recommend this place to stay."

Reviewed on May 25, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,005 reviews)
"The staff were great and very helpful. The rooms were clean but could need some updating. Great place for a convention."

Reviewed on May 24, 2026

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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Staff was awsome, rooms clean, breakfast was good."

Reviewed on May 25, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,003 reviews)
"Staff was very helpful and accommodating ."

Reviewed on May 24, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
"The room itself was clean and beds comfortable. The room was quiet. But the lock mechanism on my door would intermittently work and I got locked out 3 times and had to get my room key reprogrammed. Then the key machines went down and the concierge was as helpful as he could be. This wasn’t his fault ..."

Reviewed on May 25, 2026

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Clarion Inn Columbia Airport
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.