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South Carolina Midlands

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South Carolina Midlands Flights as Low as $186

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Tue, Sep 15 - Tue, Sep 29
DCA
Ronald Reagan Washington National
CLT
Charlotte-Douglas Intl.
$186 Roundtrip, found 5 days ago
$186
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Tue, Sep 15 from Ronald Reagan Washington National to Charlotte-Douglas Intl., returning Tue, Sep 29, priced at $186 found 5 days ago
American Airlines
Wed, Jul 8 - Tue, Jul 21
DCA
Ronald Reagan Washington National
CLT
Charlotte-Douglas Intl.
$209 Roundtrip, found 4 days ago
$209
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Jul 8 from Ronald Reagan Washington National to Charlotte-Douglas Intl., returning Tue, Jul 21, priced at $209 found 4 days ago
Bargain Flight
Wed, Aug 19 - Tue, Sep 1
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$211 Roundtrip, just found
$211
Roundtrip
just found
Select Bargain Flight flight, departing Wed, Aug 19 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Sep 1, priced at $211 just found
Delta
Wed, Jul 8 - Tue, Jul 21
DCA
Ronald Reagan Washington National
CLT
Charlotte-Douglas Intl.
$229 Roundtrip, found 4 days ago
$229
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jul 8 from Ronald Reagan Washington National to Charlotte-Douglas Intl., returning Tue, Jul 21, priced at $229 found 4 days ago
Frontier Airlines
Tue, Aug 4 - Wed, Aug 5
ATL
Hartsfield-Jackson Atlanta Intl.
CLT
Charlotte-Douglas Intl.
$230 Roundtrip, found 4 days ago
$230
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Aug 4 from Hartsfield-Jackson Atlanta Intl. to Charlotte-Douglas Intl., returning Wed, Aug 5, priced at $230 found 4 days ago
Frontier Airlines
Wed, Aug 19 - Tue, Sep 1
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$230 Roundtrip, just found
$230
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, Aug 19 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Sep 1, priced at $230 just found
American Airlines
Tue, Jun 30 - Tue, Jul 7
DCA
Ronald Reagan Washington National
CAE
Columbia Metropolitan
$255 Roundtrip, found 22 hours ago
$255
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Jun 30 from Ronald Reagan Washington National to Columbia Metropolitan, returning Tue, Jul 7, priced at $255 found 22 hours ago
Delta
Sat, Nov 14 - Tue, Nov 17
ATL
Hartsfield-Jackson Atlanta Intl.
AGS
Augusta Regional
$259 Roundtrip, found 12 hours ago
$259
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Nov 14 from Hartsfield-Jackson Atlanta Intl. to Augusta Regional, returning Tue, Nov 17, priced at $259 found 12 hours ago
Delta
Wed, Aug 5 - Mon, Aug 10
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Columbia Metropolitan, returning Mon, Aug 10, priced at $259 found 6 days ago
Bargain Flight
Fri, Jun 5 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
CAE
Columbia Metropolitan
$263 Roundtrip, found 6 hours ago
$263
Roundtrip
found 6 hours ago
Select Bargain Flight flight, departing Fri, Jun 5 from Detroit Metropolitan Wayne County to Columbia Metropolitan, returning Sat, Jun 6, priced at $263 found 6 hours ago
Delta
Tue, Jun 16 - Tue, Jun 23
DCA
Ronald Reagan Washington National
AGS
Augusta Regional
$292 Roundtrip, found 6 days ago
$292
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jun 16 from Ronald Reagan Washington National to Augusta Regional, returning Tue, Jun 23, priced at $292 found 6 days ago
Delta
Wed, Sep 9 - Sat, Sep 12
DAL
Love Field
CLT
Charlotte-Douglas Intl.
$293 Roundtrip, found 22 hours ago
$293
Roundtrip
found 22 hours ago
Select Delta flight, departing Wed, Sep 9 from Love Field to Charlotte-Douglas Intl., returning Sat, Sep 12, priced at $293 found 22 hours ago
Delta
Tue, Jul 7 - Tue, Jul 21
DTW
Detroit Metropolitan Wayne County
AGS
Augusta Regional
$347 Roundtrip, found 6 days ago
$347
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jul 7 from Detroit Metropolitan Wayne County to Augusta Regional, returning Tue, Jul 21, priced at $347 found 6 days ago
Delta
Wed, Sep 9 - Sat, Sep 12
DAL
Love Field
CAE
Columbia Metropolitan
$387 Roundtrip, found 11 hours ago
$387
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Sep 9 from Love Field to Columbia Metropolitan, returning Sat, Sep 12, priced at $387 found 11 hours ago
Delta
Tue, Dec 22 - Tue, Dec 29
DAL
Love Field
AGS
Augusta Regional
$461 Roundtrip, found 3 days ago
$461
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 22 from Love Field to Augusta Regional, returning Tue, Dec 29, priced at $461 found 3 days ago
American Airlines
Thu, Jul 23 - Fri, Jul 31
DTW
Detroit Metropolitan Wayne County
FLO
Florence Regional
$555 Roundtrip, found 6 days ago
$555
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 23 from Detroit Metropolitan Wayne County to Florence Regional, returning Fri, Jul 31, priced at $555 found 6 days ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $186, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $186 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$181

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,070 reviews)
"Well, i was stuck in the elevator, but it was okay! They cgave free tampons and pads when my gf had period so amazing!"

Reviewed on May 23, 2026

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Hilton Garden Inn Columbia/Harbison
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,672 reviews)
"Housekeeping started knocking on the door at 10:30 am to hurry me out! I was about to walk out the door in 10 minutes! And housekeeping left the soap from the previous rooms there in the bathtub! Everything else was clean"

Reviewed on May 24, 2026

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Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (153 reviews)
"The refrigerator was dirty and didn’t work, bugs on the floor in the bathroom and the room smelled like mildew and musk. The door didn’t close on the bathroom and the lock was broken."

Reviewed on May 24, 2026

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Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,276 reviews)
"La pisina no funciona por lo demas hermoso"

Reviewed on May 24, 2026

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Park Inn by Radisson Florence, SC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
8/10 Very Good! (1,004 reviews)
"My stay was very comfortable and I was able to relax and enjoy myself. Everyone was very helpful and the property is very clean. Rooms are very nice and clean. Food was good . The eggs could be scrambled instead of frozen round eggs. But I will be visiting again😊"

Reviewed on May 24, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,085 reviews)
"Loves the property"

Reviewed on May 24, 2026

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Sleep Inn Columbia
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (670 reviews)
"Beautiful property and rooms, Bar/Restaurant was excellent with complementary wine/beer and appetizers our second night for a special event they were having with guests invited, Staff was very friendly with helpful information on area sites. Breakfast was amazing with a wide array of items to choose ..."

Reviewed on May 24, 2026

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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,011 reviews)
"Unfortunately our room was sub par as far as cleanliness. I told the front desk after checking in that the toilet seemed dirty with some type of residue on the base and floor. Although they apologized nothing was done . The next morning checking out I mentioned it again and said no one followed thru ..."

Reviewed on May 24, 2026

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Courtyard by Marriott Columbia Downtown at USC
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.6/10 (1,001 reviews)
"had to switch rooms twice one tv was broken the other room no shower head and the last room we had there was cockroaches"

Reviewed on May 17, 2026

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Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,006 reviews)
"Room was pretty clean in the right areas but the corners of the rooms held a lot of build up. Great price though! Breakfastwas fantastic and larger than most. Rooms were quiet. Door in the bathroom opened against the shower and blocked it weirdly though. Lovely staff!"

Reviewed on May 24, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,004 reviews)
"I would highly recommend this hotel. It's close to downtown Columbia, and the rooms were updated and clean. The staff is friendly everywhere. The gym, pool and food/beverages at Columbo's was excellent! I will stay here again when needed."

Reviewed on May 22, 2026

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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"Libby and breakfast area was nice and clean. Room wasn’t as clean."

Reviewed on May 17, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
"Wonderful stay as always. The Bar and Restaurant are really good with helpful staff and delicious meals. For breakfast April was the best !!!"

Reviewed on May 22, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,004 reviews)
"Pretty clean quit hair dryer wasn't working"

Reviewed on May 21, 2026

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Clarion Inn Columbia Airport
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.