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South Carolina Midlands

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South Carolina Midlands Flights as Low as $251

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Thu, May 28 - Tue, Jun 2
BOS
Logan Intl.
CLT
Charlotte-Douglas Intl.
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, May 28 from Logan Intl. to Charlotte-Douglas Intl., returning Tue, Jun 2, priced at $251 found 1 day ago
American Airlines
Sat, Sep 26 - Tue, Sep 29
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$257 Roundtrip, found 8 hours ago
$257
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Sep 26 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Tue, Sep 29, priced at $257 found 8 hours ago
United
Thu, Sep 24 - Sun, Sep 27
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$259 Roundtrip, found 1 hour ago
$259
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Sep 24 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Sun, Sep 27, priced at $259 found 1 hour ago
Frontier Airlines
Thu, Sep 24 - Sun, Sep 27
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$264 Roundtrip, found 1 hour ago
$264
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Thu, Sep 24 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Sun, Sep 27, priced at $264 found 1 hour ago
Delta
Sat, Oct 17 - Tue, Oct 27
EWR
Newark Liberty Intl. Airport
AGS
Augusta Regional
$277 Roundtrip, found 2 days ago
$277
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Oct 17 from Newark Liberty Intl. Airport to Augusta Regional, returning Tue, Oct 27, priced at $277 found 2 days ago
American Airlines
Tue, Sep 15 - Tue, Sep 22
BOS
Logan Intl.
AGS
Augusta Regional
$277 Roundtrip, found 1 hour ago
$277
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Sep 15 from Logan Intl. to Augusta Regional, returning Tue, Sep 22, priced at $277 found 1 hour ago
Delta
Tue, Sep 15 - Tue, Sep 22
BOS
Logan Intl.
AGS
Augusta Regional
$277 Roundtrip, found 1 hour ago
$277
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Sep 15 from Logan Intl. to Augusta Regional, returning Tue, Sep 22, priced at $277 found 1 hour ago
American Airlines
Mon, Jun 15 - Tue, Jun 23
BOS
Logan Intl.
CAE
Columbia Metropolitan
$286 Roundtrip, found 2 days ago
$286
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 15 from Logan Intl. to Columbia Metropolitan, returning Tue, Jun 23, priced at $286 found 2 days ago
American Airlines
Tue, Sep 15 - Tue, Sep 22
OMA
Eppley Field
CAE
Columbia Metropolitan
$291 Roundtrip, found 1 day ago
$291
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 15 from Eppley Field to Columbia Metropolitan, returning Tue, Sep 22, priced at $291 found 1 day ago
United
Sat, Jul 4 - Mon, Jul 20
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$296 Roundtrip, found 3 days ago
$296
Roundtrip
found 3 days ago
Select United flight, departing Sat, Jul 4 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Mon, Jul 20, priced at $296 found 3 days ago
Frontier Airlines
Tue, Jun 9 - Tue, Jun 23
SFO
San Francisco Intl.
CLT
Charlotte-Douglas Intl.
$328 Roundtrip, found 6 days ago
$328
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Tue, Jun 9 from San Francisco Intl. to Charlotte-Douglas Intl., returning Tue, Jun 23, priced at $328 found 6 days ago
Bargain Flight
Sat, Jun 13 - Tue, Jun 16
OMA
Eppley Field
CLT
Charlotte-Douglas Intl.
$345 Roundtrip, found 3 days ago
$345
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Sat, Jun 13 from Eppley Field to Charlotte-Douglas Intl., returning Tue, Jun 16, priced at $345 found 3 days ago
Delta
Sat, Jun 20 - Tue, Jun 30
OMA
Eppley Field
AGS
Augusta Regional
$363 Roundtrip, found 4 days ago
$363
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jun 20 from Eppley Field to Augusta Regional, returning Tue, Jun 30, priced at $363 found 4 days ago
JetBlue Airways
Sat, Sep 26 - Tue, Sep 29
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$383 Roundtrip, found 8 hours ago
$383
Roundtrip
found 8 hours ago
Select JetBlue Airways flight, departing Sat, Sep 26 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Tue, Sep 29, priced at $383 found 8 hours ago
Delta
Wed, Aug 5 - Tue, Aug 25
SFO
San Francisco Intl.
AGS
Augusta Regional
$419 Roundtrip, found 17 hours ago
$419
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Aug 5 from San Francisco Intl. to Augusta Regional, returning Tue, Aug 25, priced at $419 found 17 hours ago
Alaska Airlines
Sat, Sep 26 - Sat, Oct 3
SFO
San Francisco Intl.
CLT
Charlotte-Douglas Intl.
$561 Roundtrip, found 3 days ago
$561
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Sat, Sep 26 from San Francisco Intl. to Charlotte-Douglas Intl., returning Sat, Oct 3, priced at $561 found 3 days ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $251, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $251 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$181

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,072 reviews)
"Well, i was stuck in the elevator, but it was okay! They cgave free tampons and pads when my gf had period so amazing!"

Reviewed on May 23, 2026

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Hilton Garden Inn Columbia/Harbison
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Howard Johnson by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (153 reviews)
"The refrigerator was dirty and didn’t work, bugs on the floor in the bathroom and the room smelled like mildew and musk. The door didn’t close on the bathroom and the lock was broken."

Reviewed on May 24, 2026

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Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,276 reviews)
"La pisina no funciona por lo demas hermoso"

Reviewed on May 24, 2026

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Park Inn by Radisson Florence, SC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
8/10 Very Good! (1,004 reviews)
"My stay was very comfortable and I was able to relax and enjoy myself. Everyone was very helpful and the property is very clean. Rooms are very nice and clean. Food was good . The eggs could be scrambled instead of frozen round eggs. But I will be visiting again😊"

Reviewed on May 24, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,086 reviews)
"Loves the property"

Reviewed on May 24, 2026

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Sleep Inn Columbia
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (670 reviews)
"Beautiful property and rooms, Bar/Restaurant was excellent with complementary wine/beer and appetizers our second night for a special event they were having with guests invited, Staff was very friendly with helpful information on area sites. Breakfast was amazing with a wide array of items to choose ..."

Reviewed on May 24, 2026

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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,011 reviews)
"Unfortunately our room was sub par as far as cleanliness. I told the front desk after checking in that the toilet seemed dirty with some type of residue on the base and floor. Although they apologized nothing was done . The next morning checking out I mentioned it again and said no one followed thru ..."

Reviewed on May 24, 2026

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Courtyard by Marriott Columbia Downtown at USC
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.6/10 (1,001 reviews)
"had to switch rooms twice one tv was broken the other room no shower head and the last room we had there was cockroaches"

Reviewed on May 17, 2026

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Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,006 reviews)
"Room was pretty clean in the right areas but the corners of the rooms held a lot of build up. Great price though! Breakfastwas fantastic and larger than most. Rooms were quiet. Door in the bathroom opened against the shower and blocked it weirdly though. Lovely staff!"

Reviewed on May 24, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,005 reviews)
"The staff were great and very helpful. The rooms were clean but could need some updating. Great place for a convention."

Reviewed on May 24, 2026

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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Staff was awsome, rooms clean, breakfast was good."

Reviewed on May 25, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,003 reviews)
"Staff was very helpful and accommodating ."

Reviewed on May 24, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,004 reviews)
"Pretty clean quit hair dryer wasn't working"

Reviewed on May 21, 2026

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Clarion Inn Columbia Airport
See all 3,291 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.