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South Carolina Midlands

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South Carolina Midlands Flights as Low as $220

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Nov 21 - Wed, Nov 25
SAT
San Antonio Intl.
CLT
Charlotte-Douglas Intl.
$220 Roundtrip, just found
$220
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Nov 21 from San Antonio Intl. to Charlotte-Douglas Intl., returning Wed, Nov 25, priced at $220 just found
Frontier Airlines
Sat, Nov 14 - Sat, Dec 5
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$230 Roundtrip, found 5 hours ago
$230
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Sat, Nov 14 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Sat, Dec 5, priced at $230 found 5 hours ago
Frontier Airlines
Sat, Nov 21 - Wed, Nov 25
SAT
San Antonio Intl.
CLT
Charlotte-Douglas Intl.
$230 Roundtrip, just found
$230
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Nov 21 from San Antonio Intl. to Charlotte-Douglas Intl., returning Wed, Nov 25, priced at $230 just found
Bargain Flight
Wed, Feb 24 - Mon, Mar 1
BOS
Logan Intl.
CLT
Charlotte-Douglas Intl.
$248 Roundtrip, found 4 hours ago
$248
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Wed, Feb 24 from Logan Intl. to Charlotte-Douglas Intl., returning Mon, Mar 1, priced at $248 found 4 hours ago
Bargain Flight
Tue, Nov 17 - Wed, Dec 2
BOS
Logan Intl.
CAE
Columbia Metropolitan
$255 Roundtrip, found 19 hours ago
$255
Roundtrip
found 19 hours ago
Select Bargain Flight flight, departing Tue, Nov 17 from Logan Intl. to Columbia Metropolitan, returning Wed, Dec 2, priced at $255 found 19 hours ago
American Airlines
Wed, Dec 16 - Tue, Jan 5
EWR
Newark Liberty Intl. Airport
AGS
Augusta Regional
$259 Roundtrip, just found
$259
Roundtrip
just found
Select American Airlines flight, departing Wed, Dec 16 from Newark Liberty Intl. Airport to Augusta Regional, returning Tue, Jan 5, priced at $259 just found
Southwest Airlines
Wed, Jan 13 - Tue, Jan 19
DAL
Love Field
CLT
Charlotte-Douglas Intl.
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Wed, Jan 13 from Love Field to Charlotte-Douglas Intl., returning Tue, Jan 19, priced at $283 found 2 hours ago
Delta
Tue, Dec 15 - Mon, Jan 4
EWR
Newark Liberty Intl. Airport
AGS
Augusta Regional
$289 Roundtrip, found 19 hours ago
$289
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Dec 15 from Newark Liberty Intl. Airport to Augusta Regional, returning Mon, Jan 4, priced at $289 found 19 hours ago
Delta
Fri, Dec 25 - Wed, Dec 30
DAL
Love Field
AGS
Augusta Regional
$351 Roundtrip, found 5 days ago
$351
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Dec 25 from Love Field to Augusta Regional, returning Wed, Dec 30, priced at $351 found 5 days ago
United
Mon, Nov 16 - Thu, Nov 26
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$359 Roundtrip, found 8 hours ago
$359
Roundtrip
found 8 hours ago
Select United flight, departing Mon, Nov 16 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Thu, Nov 26, priced at $359 found 8 hours ago
Bargain Flight
Wed, Dec 2 - Wed, Dec 2
SAT
San Antonio Intl.
CAE
Columbia Metropolitan
$360 Roundtrip, found 13 hours ago
$360
Roundtrip
found 13 hours ago
Select Bargain Flight flight, departing Wed, Dec 2 from San Antonio Intl. to Columbia Metropolitan, returning Wed, Dec 2, priced at $360 found 13 hours ago
Delta
Sat, Jan 23 - Sat, Jan 30
DAL
Love Field
CAE
Columbia Metropolitan
$385 Roundtrip, just found
$385
Roundtrip
just found
Select Delta flight, departing Sat, Jan 23 from Love Field to Columbia Metropolitan, returning Sat, Jan 30, priced at $385 just found
American Airlines
Tue, Nov 17 - Wed, Dec 2
SAT
San Antonio Intl.
AGS
Augusta Regional
$404 Roundtrip, found 5 hours ago
$404
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 17 from San Antonio Intl. to Augusta Regional, returning Wed, Dec 2, priced at $404 found 5 hours ago
American Airlines
Tue, Nov 3 - Sat, Nov 7
BOS
Logan Intl.
AGS
Augusta Regional
$417 Roundtrip, found 4 hours ago
$417
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Nov 3 from Logan Intl. to Augusta Regional, returning Sat, Nov 7, priced at $417 found 4 hours ago
JetBlue Airways
Sat, Nov 14 - Sat, Dec 5
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$458 Roundtrip, found 5 hours ago
$458
Roundtrip
found 5 hours ago
Select JetBlue Airways flight, departing Sat, Nov 14 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Sat, Dec 5, priced at $458 found 5 hours ago
American Airlines
Mon, Nov 23 - Wed, Dec 2
SAT
San Antonio Intl.
FLO
Florence Regional
$513 Roundtrip, found 1 day ago
$513
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 23 from San Antonio Intl. to Florence Regional, returning Wed, Dec 2, priced at $513 found 1 day ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in November, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $220, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $220 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$43

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
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Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Colonial ...
8.4/10 Very Good! (1,016 reviews)
"Elevator floor was very dirty and super sticky"

Reviewed on Oct 31, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,216 reviews)
"Friendly staffs. Affordable stay inn"

Reviewed on Oct 30, 2026

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Sleep Inn Columbia
Clarion Pointe Rock Hill Near University

Clarion Pointe Rock Hill Near University

2.5 out of 5
1106 N. Anderson Road Rock Hill SC
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
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Clarion Pointe Rock Hill Near University
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...
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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
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Courtyard by Marriott Columbia Downtown at USC
Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

2.5 out of 5
185 Stoneridge Drive Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Tru By Hilton Columbia Greystone
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.8/10 Good! (1,179 reviews)
"So many things broken. Exercise room out of order, waffle maker out of order, thermostat in room broken, faucet broken, pieces of wall falling apart."

Reviewed on Oct 31, 2026

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Country Inn & Suites by Radisson, Columbia, SC
See all 3,384 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and Colonial ...
5.8/10 (1,001 reviews)
"Nothing like the photos show not much works and the hallways are nasty there’s mold and the paint on the ceiling is peeling off it takes like 10 minutes to get hot water it’s just nasty"

Reviewed on Oct 30, 2026

Get rates
Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
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Clarion Inn Columbia Airport
See all 3,384 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.