Search for Cheap Deals on
Hotels in Middletown Station

Choose from 5301 Middletown Station Hotel Deals

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
  • 5 min drive from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9/10 Wonderful! (3,351 reviews)
The staff is amazing. Everyone acted like they actually enjoyed their jobs…we always felt very welcome. The food was terrific…Happy Hour snacks (crab tater tots, sliders), dinner entrees (Colette steak, pasta, brown sugar glazed pork), hamburgers and best breakfast I’ve ever had — crab tater tot ...

Reviewed on Feb 1, 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
  • 5 min drive from San Diego Zoo
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
8.8/10 Excellent! (3,279 reviews)
Staff was nice and helpful

Reviewed on Jan 30, 2026

Hard Rock Hotel San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
  • 7 min drive from San Diego Zoo
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (2,389 reviews)
Room was cleaned, but the restaurants in premises close early

Reviewed on Jan 31, 2026

Paradise Point Resort & Spa
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
  • 19 min walk from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (997 reviews)
This is the second time we stayed there. Room is very clean and friendly staff. We will choose the same hotel next time in San Diego.

Reviewed on Feb 1, 2026

The DEXTRO Little Italy, BW Premier Collection
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
  • 8 min drive from San Diego Zoo
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,340 reviews)
Great room, great amenities, the resort was so nice.

Reviewed on Jan 21, 2026

San Diego Mission Bay Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
  • 28 min walk from San Diego Zoo
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,732 reviews)
Excellent location! The staff was friendly and the hotel is lovely. Our room was nice and spacious, and the bed was very comfortable. I would not hesitate to stay here again in the future.

Reviewed on Jan 29, 2026

The Sofia Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
  • 6 min drive from San Diego Zoo
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (4,043 reviews)
The room was good, quite, staff are nice, location is good . The first night the AC wasn’t working and there was no one after hours to fix it which made the night freezing the second night they fixed it.

Reviewed on Jan 31, 2026

The Dana on Mission Bay
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
  • 4 min drive from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.8/10 Good! (3,181 reviews)
Room was clean and functional.

Reviewed on Jan 31, 2026

Best Western Seven Seas
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St San Diego CA
  • 4 min drive from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
9.2/10 Wonderful! (586 reviews)
Rooms were very accommodating and clean and good size. The staff were helpful and friendly. I highly recommend staying here

Reviewed on Jan 30, 2026

Hampton Inn & Suites by Hilton San Diego SeaWorld
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
  • 24 min walk from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,013 reviews)
Room was c

Reviewed on Jan 29, 2026

Wyndham San Diego Bayside
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
  • 4 min drive from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
7.8/10 Good! (2,448 reviews)
Great

Reviewed on Jan 29, 2026

Days Inn by Wyndham San Diego Hotel Circle
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
  • 5 min drive from San Diego Zoo
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8/10 Very Good! (2,311 reviews)
Staff was helpful

Reviewed on Jan 31, 2026

Hilton San Diego Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.