Search for Cheap Deals onSpa Resort Hotels in St. Charles
Check Last Minute St. Charles Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured St. Charles Resorts & Hotels with Spas
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Research Park Inn St Louis West – Chesterfield
32 Research Park Circle, St. Charles, MO
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz, St. Charles, MO
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn St. Charles St. Peters
3720 W Clay St, St. Charles, MO
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
St. Charles Neighborhoods
Top Points of Interests in St. Charles
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Jaycee Park
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Missouri Artists on Main
- Hotels near Frenchtown Heritage Museum
- Hotels near Mississippi River
- Hotels near Missouri River
Cities near St. Charles
- Maryland Heights Hotels (6.33 mi)
- Chesterfield Hotels (9.49 mi)
- Hazelwood Hotels (6.19 mi)
- O'Fallon Hotels (11 mi)
- Innsbrook Hotels (29.82 mi)
- St. Peters Hotels (6.7 mi)
- Collinsville Hotels (28.73 mi)
- Ozarks Hotels (156.82 mi)
- Alton Hotels (18.27 mi)
- Fenton Hotels (19.25 mi)
- Richmond Heights Hotels (14.6 mi)
- Eureka Hotels (20.94 mi)
- Grafton Hotels (13.05 mi)
- Wentzville Hotels (19.2 mi)
- Edwardsville Hotels (27.79 mi)
- East St. Louis Hotels (22.41 mi)
- Bridgeton Hotels (4.85 mi)
- Kirkwood Hotels (14.96 mi)
- Arnold Hotels (25.37 mi)
- Washington Hotels (31.97 mi)
Car Rentals Near St. Charles
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in Hazelwood
- Car rentals in O'Fallon
- Car rentals in Innsbrook
- Car rentals in St. Peters
- Car rentals in Collinsville
- Car rentals in Ozarks
- Car rentals in Alton
- Car rentals in Fenton
- Car rentals in Richmond Heights
- Car rentals in Eureka
- Car rentals in Grafton
- Car rentals in Wentzville
- Car rentals in Edwardsville
- Car rentals in East St. Louis
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in St. Charles
- Ameristar Casino Resort and Spa
- Relax Inn Saint Charles
- Best Western Plus The Charles Hotel
- Country Inn & Suites by Radisson, St. Charles Historic District
- Hyatt Regency St. Louis at The Arch
- Hollywood Casino & Hotel St. Louis
- Clayton Plaza Hotel & Extended Stay
- River City Casino & Hotel
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza