Search Cheap Flights to
St. Charles

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

St. Charles Flights as Low as $51

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sun, Sep 6 - Mon, Sep 21
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$51 Roundtrip, found 15 hours ago
$51
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Sep 21, priced at $51 found 15 hours ago
Frontier Airlines
Sun, Sep 6 - Fri, Sep 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$56 Roundtrip, found 15 hours ago
$56
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Sun, Sep 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Sep 25, priced at $56 found 15 hours ago
Frontier Airlines
Fri, Oct 30 - Thu, Nov 19
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$80 Roundtrip, found 1 day ago
$80
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Oct 30 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Nov 19, priced at $80 found 1 day ago
Frontier Airlines
Fri, Sep 11 - Wed, Sep 16
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$88 Roundtrip, found 1 day ago
$88
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Sep 11 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Sep 16, priced at $88 found 1 day ago
Southwest Airlines
Sat, Oct 31 - Sat, Oct 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$100 Roundtrip, found 9 hours ago
$100
Roundtrip
found 9 hours ago
Select Southwest Airlines flight, departing Sat, Oct 31 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Oct 31, priced at $100 found 9 hours ago
Delta
Sat, Oct 31 - Sat, Oct 31
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$112 Roundtrip, found 9 hours ago
$112
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Oct 31 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Oct 31, priced at $112 found 9 hours ago
Frontier Airlines
Thu, Oct 22 - Mon, Oct 26
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$152 Roundtrip, found 11 hours ago
$152
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Thu, Oct 22 from Orlando Intl. to Lambert-St. Louis Intl., returning Mon, Oct 26, priced at $152 found 11 hours ago
American Airlines
Tue, Oct 27 - Tue, Nov 17
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$159 Roundtrip, found 2 hours ago
$159
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Nov 17, priced at $159 found 2 hours ago
United
Tue, Oct 27 - Tue, Nov 17
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$170 Roundtrip, found 2 hours ago
$170
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Oct 27 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Nov 17, priced at $170 found 2 hours ago
Southwest Airlines
Fri, Oct 30 - Thu, Nov 19
DAL
Love Field
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 8 hours ago
$179
Roundtrip
found 8 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from Love Field to Lambert-St. Louis Intl., returning Thu, Nov 19, priced at $179 found 8 hours ago
Frontier Airlines
Mon, Nov 2 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$199 Roundtrip, found 1 day ago
$199
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 2 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Wed, Nov 4, priced at $199 found 1 day ago
Frontier Airlines
Sat, Sep 12 - Mon, Sep 14
DCA
Ronald Reagan Washington National
STL
Lambert-St. Louis Intl.
$201 Roundtrip, found 18 hours ago
$201
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Sat, Sep 12 from Ronald Reagan Washington National to Lambert-St. Louis Intl., returning Mon, Sep 14, priced at $201 found 18 hours ago
Frontier Airlines
Fri, Oct 23 - Fri, Nov 6
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$208 Roundtrip, found 6 days ago
$208
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Oct 23 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Fri, Nov 6, priced at $208 found 6 days ago
Southwest Airlines
Mon, Oct 5 - Fri, Oct 9
FLL
Fort Lauderdale - Hollywood Intl.
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 16 hours ago
$257
Roundtrip
found 16 hours ago
Select Southwest Airlines flight, departing Mon, Oct 5 from Fort Lauderdale - Hollywood Intl. to Lambert-St. Louis Intl., returning Fri, Oct 9, priced at $257 found 16 hours ago
American Airlines
Wed, Sep 23 - Sat, Oct 10
LBB
Preston Smith Intl.
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 17 hours ago
$257
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Sep 23 from Preston Smith Intl. to Lambert-St. Louis Intl., returning Sat, Oct 10, priced at $257 found 17 hours ago
Alaska Airlines
Mon, Aug 31 - Sun, Sep 6
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$393 Roundtrip, found 6 days ago
$393
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Mon, Aug 31 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sun, Sep 6, priced at $393 found 6 days ago

Cheap Flights to St. Charles

Fall in love at first flight with your vacation to St. Charles by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to St. Charles on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in St. Charles, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to St. Charles

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to St. Charles with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to St. Charles?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to St. Charles are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to St. Charles?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to St. Charles.

What airport is best to fly into St. Charles?

When you’re planning your trip to St. Charles, convenience is the name of the game. Luckily, St. Charles Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your St. Charles must-do list.

How much are flights to St. Charles?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to St. Charles on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $51, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to St. Charles?

The trick to saving a stack of cash on your flight to St. Charles? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $51 right now, why wait?

St. Charles Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$51

Last Minute Hotel Deals in St. Charles

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,000 reviews)
"The hotel is in excellent condition. It’s either new or newly remodeled. Bed was super comfortable and pillows awesome. The breakfast area offered a lot to choose from. I highly recommend this hotel at this location in St Charles MO and would definitely stay again. Hotel exit is right off the highway ..."

Reviewed on Aug 12, 2026

Get rates
Hampton Inn St. Charles St. Peters
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Get rates
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Get rates
Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Get rates
Hollywood Casino & Hotel St. Louis
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Get rates
Renaissance St. Louis Airport Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,523 reviews)
"Had a fantastic stay at Heritage Inn and Suites in Fenton! The hotel was clean, quiet, and extremely safe for a solo female traveler—plus, the bed was so comfortable I slept 8.5 hours straight. The staff was super friendly, the water pressure was great, and the hot breakfast of biscuits, sausage, ..."

Reviewed on Aug 14, 2026

Get rates
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
Get rates
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Get rates
Pear Tree Inn St. Louis Near Union Station
See all 2,457 properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.