Hotels Near
Santa Cruz

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Featured Santa Cruz Hotels

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Seville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,001 reviews)
excelente hotel

Reviewed on Jan 31, 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,528 reviews)
The room was clean , spacious and beautiful! The staff was generous with their time and very helpful. Great location.

Reviewed on Jan 26, 2026

Hotel Fernando III
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in ...
9.6/10 Exceptional! (1,122 reviews)
Yes, excellent property. Other than when they tried to give us American drip coffee instead of cafe con leche. Staff, room and location-pefect.

Reviewed on Jan 29, 2026

Hotel Amadeus Sevilla
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,133 reviews)
The staff and the hotel were great! The staff were very friendly and helpful. Room was very clean and spacious. Definitely will be staying there again during my next visit to Sevilla. Thank you for everything!!!

Reviewed on Jan 25, 2026

Hotel Rey Alfonso X
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (996 reviews)
Great property

Reviewed on Jan 28, 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Seville. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,005 reviews)
The room was well put together upon arrival the staff provided excellent service, including a map with landmarks and local shops that she pointed out to me.

Reviewed on Jan 20, 2026

Hotel Murillo
Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla

4 out of 5
Don Carlos Alonso Chaparro 3 Seville Seville
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (879 reviews)
Very clean and staff very courteous

Reviewed on Jan 26, 2026

Hotel Boutique Casa del Poeta Sevilla
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (994 reviews)
Room was clean enough. Few staff not very approachable.

Reviewed on Jan 26, 2026

Hotel Doña Maria
Petit Palace Santa Cruz

Petit Palace Santa Cruz

4 out of 5
Munoz y Pabón 18 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
9/10 Wonderful! (958 reviews)
The room had a nice terrace over the courtyard and had tons of storage and amenities. It was a little loud, but the location was great!

Reviewed on Dec 26, 2025

Petit Palace Santa Cruz
Hotel Murillo Reinoso

Hotel Murillo Reinoso

2 out of 5
Lope de Rueda, 16 Seville Seville
Fully refundableReserve now, pay when you stay
Stay at this hotel in Seville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (72 reviews)
Lovely hotel great price central Location

Reviewed on Jan 23, 2026

Hotel Murillo Reinoso
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

4 out of 5
Calle Abades 41-43 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this boutique hotel in Seville. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (496 reviews)
We very much enjoyed our stay here. Excellent location. I would recommend.

Reviewed on Jan 17, 2026

Eurostars Sevilla Boutique
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

5 out of 5
Calle Alemanes 27 Seville Seville
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Seville. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (989 reviews)
Spacious Room. Good for families.

Reviewed on Jan 9, 2026

EME Catedral Mercer Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz

Seville is a city that has a lot going on, but you have your sights set on Santa Cruz. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Santa Cruz has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Santa Cruz hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Seville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Santa Cruz underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Santa Cruz city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Santa Cruz cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Santa Cruz at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $92
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Santa Cruz hotel you want, book it, and never look back. Because your great escape is ahead of you.