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Featured South Loop Resorts & Hotels with Spas

Estimated price for 1 night/2 adults

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Recently Booked South Loop Spa Resorts

South Loop Hotel Guide

Search for hotels in South Loop on Hotwire. You can easily find your hotels in South Loop using one of the methods below:

  • View our selection of featured hotels in South Loop
  • Use the map to find hotels in the South Loop neighborhood you prefer
  • Use the filters to see hotels in a specific area of South Loop, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in South Loop
  • Enter your travel dates to view the best deals on hotels in South Loop - while they last