Hotels Near
Puerto Santa Ana

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Featured Puerto Santa Ana Hotels

Wyndham Guayaquil Puerto Santa Ana
Wyndham Guayaquil Puerto Santa Ana
4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
"Great staff. Very helpful, friendly and warm."

Reviewed on Jun 22, 2025

Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE
Luxury Suites Riverfront GYE
3.5 out of 5
Puerto Santa Ana, Guayaquil, Guayas
Stay at this 3.5-star aparthotel in Guayaquil. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Santa Ana Hill and Botanical Garden ...
9.2/10 Wonderful! (90 reviews)
"The property is close to the Malecon and airport. The shades and windows were dirty. It looked a bit drab inside."

Reviewed on May 15, 2025

Luxury Suites Riverfront GYE
River View suites Puerto Santa Ana gye
River View suites Puerto Santa Ana gye
3 out of 5
Puerto Santa Ana, Edificios Riverfront, Bellini, junto al hotel Wyndham., Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 3-star apartment in Guayaquil. Enjoy free WiFi, a rooftop terrace, and a fitness center. Popular attractions Santa Ana Hill and Botanical Garden ...
8.2/10 Very Good! (34 reviews)
"Agradable experiencia! Buena comunicación"

Reviewed on Mar 24, 2025

River View suites Puerto Santa Ana gye
Departamento de lujo Bellini 1203
Departamento de lujo Bellini 1203
2.5 out of 5
3er Callejon 11 NE, 1203, Guayaquil, Guayas
Stay at this apartment in Guayaquil. Enjoy free WiFi, a 24-hour front desk, and in-room washers/dryers. Popular attractions Botanical Garden and Santa Ana Garden ...
Departamento de lujo Bellini 1203
Santa Ana Guayaquil Lux Coliving Ecuador
Santa Ana Guayaquil Lux Coliving Ecuador
3 out of 5
2do Callejon 11 Northeast, Guayaquil
Fully refundable
Stay at this 3-star apartment in Guayaquil. Enjoy free WiFi, free parking, and an airport shuttle (surcharge). Popular attractions Botanical Garden and Santa ...
Excellent service and accommodations
"The owner came to meet us and showed us the apartment. He is fluent in English and he was available to answer our calls promptly. The apartment was beautifully furnished and clean. We were missing a large pot for cooking soup. He arranged for his wife to bring it to the apartment. We would definitely ..."

Reviewed on Aug 6, 2024

Santa Ana Guayaquil Lux Coliving Ecuador
Oro Verde Guayaquil
Oro Verde Guayaquil
5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (1,002 reviews)
"I will have good internet"

Reviewed on Jun 29, 2025

Oro Verde Guayaquil
Hilton Colon Guayaquil
Hilton Colon Guayaquil
4.5 out of 5
Av Francisco de Orellana Mz 111, Guayaquil
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (726 reviews)
"Very close to restaurant & stores."

Reviewed on Jun 16, 2025

Hilton Colon Guayaquil
Holiday Inn Guayaquil Airport by IHG
Holiday Inn Guayaquil Airport by IHG
3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
Fully refundable
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,007 reviews)
Great Location
"Great location for a quick night if you're coming from the US and going onto The Galapagos. $5 cab ride or set up a free shuttle through the hotel. Breakfast is a bit over-priced but the freah fruit was outstanding."

Reviewed on Jun 28, 2025

Holiday Inn Guayaquil Airport by IHG
Sheraton Guayaquil Hotel
Sheraton Guayaquil Hotel
5 out of 5
Av. Constitucion, Plaza del Sol, Frente al Mall del Sol, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (551 reviews)
"Beautiful hotel located so close to the airport and in front of very nice mall."

Reviewed on Jun 11, 2025

Sheraton Guayaquil Hotel
Ibis Styles El Malecon Guayaquil
Ibis Styles El Malecon Guayaquil
4 out of 5
Av Malecon Simon Bolivar, Guayaquil
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (219 reviews)
Just a comment
"It was a good place to stay. I thought the clothes rack wasn't very well designed. It's not very comfortable. May be better."

Reviewed on May 17, 2025

Ibis Styles El Malecon Guayaquil
Courtyard by Marriott Guayaquil
Courtyard by Marriott Guayaquil
3.5 out of 5
Av. Francisco De Orellana #236, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,003 reviews)
"Very nice great view of the city. Staff very friendly Excellent service"

Reviewed on Jun 1, 2025

Courtyard by Marriott Guayaquil
Unipark by Oro Verde Hotels
Unipark by Oro Verde Hotels
4 out of 5
Clemente Ballén 406, entre Chile y Chimborazo, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9/10 Wonderful! (1,004 reviews)
"This is my second stay in this wonderful hotel, the security, comfort and hospitality is one of the reasons I highly recommend this place, breakfast is great lots of food options and since it’s a mall I had my hair colored and manicure and pedicure for only $60 dollars in Florida I pay more than ..."

Reviewed on Jun 29, 2025

Unipark by Oro Verde Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Puerto Santa Ana

Guayaquil is a city that has a lot going on, but you have your sights set on Puerto Santa Ana. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Puerto Santa Ana has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Puerto Santa Ana hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Guayaquil so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Puerto Santa Ana underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Puerto Santa Ana city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Puerto Santa Ana cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Puerto Santa Ana at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Puerto Santa Ana hotel you want, book it, and never look back. Because your great escape is ahead of you.