Hotels Near
Puerto Santa Ana

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Featured Puerto Santa Ana Hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,010 reviews)
The entire hotel looks gorgeous. The room was spotless. The staff was fantastic. I highly recommend.

Reviewed on Jan 15, 2026

Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana Guayaquil Guayas
Stay at this aparthotel in Guayaquil. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Santa Ana Hill and Botanical Garden are ...
9.2/10 Wonderful! (104 reviews)
La habitación estaba muy limpia excelente suite

Reviewed on Jan 25, 2026

Luxury Suites Riverfront GYE
River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye

3 out of 5
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Stay at this apartment in Guayaquil. Enjoy free WiFi, a rooftop terrace, and a fitness center. Popular attractions Santa Ana Hill and Botanical Garden are located ...
8.6/10 Excellent! (46 reviews)
Excellent

Reviewed on Jan 15, 2026

River View suites Puerto Santa Ana gye
Administradora Condominio Guayaquil

Administradora Condominio Guayaquil

2 out of 5
Puerto Santa Ana Guayaquil
Stay at this apartment in Guayaquil. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Santa Ana Hill and Botanical Garden ...
Administradora Condominio Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,022 reviews)
Yes

Reviewed on Jan 25, 2026

Holiday Inn Guayaquil Airport by IHG
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (1,000 reviews)
Upgrade was excellent as wss the complimentary airport transfers.

Reviewed on Jan 25, 2026

Oro Verde Guayaquil
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (836 reviews)
Yes

Reviewed on Jan 20, 2026

Hilton Colon Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,007 reviews)
Easy check-in. Nice, modern, clean room.

Reviewed on Jan 26, 2026

Wyndham Garden Guayaquil
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in our ...
8.8/10 Excellent! (1,000 reviews)
Excelentes desayunos.

Reviewed on Jan 27, 2026

TRYP by Wyndham Guayaquil Airport
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9/10 Wonderful! (1,000 reviews)
Customer service, amenities, restaurant service. Professional team. Clean room, location.

Reviewed on Jan 20, 2026

Unipark by Oro Verde Hotels
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4 out of 5
Av 33. Ciudadela La Garzota Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (233 reviews)
Great stay and great staff!

Reviewed on Jan 27, 2026

Hotel Puerto Pacifico Guayaquil Airport
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

5 out of 5
Av. Constitucion, Plaza del Sol Guayaquil Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (617 reviews)
Very Good

Reviewed on Jan 28, 2026

Sheraton Guayaquil Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Puerto Santa Ana

Guayaquil is a city that has a lot going on, but you have your sights set on Puerto Santa Ana. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Puerto Santa Ana has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Puerto Santa Ana hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Guayaquil so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Puerto Santa Ana underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Puerto Santa Ana city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Puerto Santa Ana cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Puerto Santa Ana at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $71
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Puerto Santa Ana hotel you want, book it, and never look back. Because your great escape is ahead of you.