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Guayaquil Vacation Packages

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A cityscape at sunset with a river in the foreground and a mix of high-rise and low-rise buildings.

Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Guayaquil Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Mar Azul

3.5 out of 5

Price was $287, price is now $243 per person

$243

per person

Nov 19 - Nov 22

found 18 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Manta. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mall del Pacífico and Museo del Banco Central are located nearby.

Helpful host and cafe in the hotel a plus…

Reviewed on Sep 5, 2026

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Price was $3,642, price is now $2,660 per person

$2,660

per person

Dec 22 - Dec 29

found 1 day ago

Roundtrip flight included

New York (JFK) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

Mansión Alcázar Boutique Hotel

4 out of 5

Price was $343, price is now $251 per person

$251

per person

Nov 14 - Nov 16

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Staff, breakfast

Reviewed on Oct 6, 2026

Hotel Boutique Santa Lucia

4 out of 5

Price was $338, price is now $250 per person

$250

per person

Nov 20 - Nov 22

found 15 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this boutique hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Calderon Park and Cúpulas Lookout are located nearby.

Balandra Hotel

4 out of 5

Price was $341, price is now $283 per person

$283

per person

Nov 19 - Nov 22

found 18 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Manta. Enjoy free parking, a full-service spa, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Museo del Banco Central and Mall del Pacífico are located nearby.

Mantahost Hotel

4 out of 5

Price was $471, price is now $404 per person

$404

per person

Nov 19 - Nov 22

found 18 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this beach hotel in Manta. Enjoy free breakfast, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular attractions Plaza La Quadra and Umiña Tennis Club are located nearby.

Hotel Perla Spondylus

3.5 out of 5

Price was $296, price is now $255 per person

$255

per person

Nov 19 - Nov 22

found 18 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Manta. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Avenida Malecón and Manta Port are located nearby.

Eolia Sustainable Design Hotel

4 out of 5

Price was $403, price is now $349 per person

$349

per person

Nov 19 - Nov 22

found 18 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this beach hotel in Manta. Enjoy free breakfast, free WiFi, and a private beach. Popular attractions Playa Santa Marianita and Umiña Tennis Club are located nearby.

The property is not well maintained and under staffed. The food menu is limited

Reviewed on Jul 25, 2026