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Guayaquil Vacation Packages

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A curved pathway lined with palm trees and colorful plants, leading to a hill with colorful buildings.

Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Guayaquil Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Presidente Internacional

3.5 out of 5

Price was $303, price is now $236 per person

$236

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, room service, and a sauna. Popular attractions Centennial Park and San Francisco Square are located nearby.

Luxury Suites Riverfront GYE

3.5 out of 5

Price was $407, price is now $288 per person

$288

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this aparthotel in Guayaquil. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Santa Ana Hill and Botanical Garden are located nearby.

Hotel del Parque

4.5 out of 5

Save 100% on your flight

Price was $1,172, price is now $841 per person

$841

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Histórico Guayaquil and Guayaquil Historic Park are located nearby.

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Save 100% on your flight

Price was $1,540, price is now $1,109 per person

$1,109

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.

Reviewed on Oct 25, 2025

Hotel Marcelius

3.5 out of 5

Price was $388, price is now $298 per person

$298

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 24-hour room service. Popular attractions San Marino Mall and Supercines Orellana are located nearby.

👍👍👍

Reviewed on Aug 24, 2026

Hotel El Conquistador

4 out of 5

Price was $935, price is now $721 per person

$721

per person

Nov 2 - Nov 9

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Plaza Rotary Market and Calderon Park are located nearby.

Hotel Azul de la Plaza

3.5 out of 5

Price was $465, price is now $364 per person

$364

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Cuenca. Enjoy free breakfast, free WiFi, and room service. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Our stay was very pleasant, thanks

Reviewed on Aug 26, 2026

Hotel Air Suites

2.5 out of 5

Price was $323, price is now $258 per person

$258

per person

Oct 9 - Oct 13

found 5 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Mall del Sol Shopping Center and Antonio Neumane Park are located nearby.

The stuff is great! Thank you.

Reviewed on Aug 7, 2026