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Guayaquil Vacation Packages

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A cityscape at sunset with a river in the foreground and a mix of high-rise and low-rise buildings.

Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Guayaquil Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Ramada

3 out of 5

Price was $275, price is now $192 per person

$192

per person

Jan 11 - Jan 13

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and room service. Popular attractions Chocolate Museum and Museum of Anthropology and Contemporary Art are located nearby.

Excelente atención, good service, sauna and pull in great condition, food very good

Reviewed on Oct 24, 2026

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Save 100% on your flight

Price was $783, price is now $457 per person

$457

per person

Nov 24 - Nov 26

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

Hotel El Conquistador

4 out of 5

Price was $329, price is now $239 per person

$239

per person

Dec 4 - Dec 6

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Plaza Rotary Market and Calderon Park are located nearby.

Toallas viejas y manchadas

Reviewed on Sep 18, 2026

Hotel Marcelius

3.5 out of 5

Price was $347, price is now $252 per person

$252

per person

Dec 29 - Jan 2

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 24-hour room service. Popular attractions San Marino Mall and Supercines Orellana are located nearby.

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5

Price was $416, price is now $304 per person

$304

per person

Jan 11 - Jan 13

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this luxury hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Our room was unbearably hot. Imposible to sleep. Front desk’s response was that the city was unusually warm. Restaurant was very uneven, could be rated a 1 or a 5 depending on the day or meal.

Reviewed on Oct 24, 2026

Hotel GH Galeria

3.5 out of 5

Price was $327, price is now $241 per person

$241

per person

Dec 29 - Jan 2

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Sports Federation of Guayas and Centennial Park are located nearby.

Todo muy bien, es bien ubicado según lo que desees hacer, personal atento. Se podría mejorar el desayuno!

Reviewed on Sep 24, 2026

Mansión Alcázar Boutique Hotel

4 out of 5

Price was $326, price is now $243 per person

$243

per person

Nov 24 - Nov 26

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Great hotel and service

Reviewed on Oct 24, 2026

Hotel Boutique Santa Lucia

4 out of 5

Price was $375, price is now $280 per person

$280

per person

Dec 4 - Dec 6

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this boutique hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Calderon Park and Cúpulas Lookout are located nearby.

Guayaquil Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.

Hotel El Conquistador

4 out of 5

Downtown Cuenca

Save 100% on your flight

Price was $368, price is now $199 per person

$199

per person

Dec 3 - Dec 6

found 19 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)