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Guayaquil Vacation Packages

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A curved pathway lined with palm trees and colorful plants, leading to a hill with colorful buildings.

Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Guayaquil Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Santa Lucia Suites - Barranco

3.5 out of 5

Price was $316, price is now $243 per person

$243

per person

Aug 20 - Aug 23

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this aparthotel in Cuenca. Enjoy free WiFi, in-room massages, and an airport shuttle (surcharge). Popular attractions Inter-American Center of Popular Arts and Río Tomebamba & Calle Larga are located nearby.

Everything is excellent highly recommended to anyone ❤️

Reviewed on Jul 3, 2026

Hotel del Parque

4.5 out of 5

Save 100% on your flight

Price was $2,236, price is now $1,419 per person

$1,419

per person

Sep 10 - Sep 17

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Guayaquil (GYE)

Book a stay at this luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guayaquil Historic Park and Museum of Cocoa and Chocolate are located nearby.

We stayed for a few days, everything was clean and the attention to detail was amazing. The staff was mostly nice and welcoming except for a few interactions but overall I highly recommend this hotel

Reviewed on Jun 29, 2026

Casa Firenza

3.5 out of 5

Price was $468, price is now $307 per person

$307

per person

Aug 20 - Aug 23

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Calderon Park and Convent of the Assumption are located nearby.

Great staff, super clean and in the heart of the historical city. Can’t emphasize how well maintained and safe this hotel is. Gorgeous views and great food too! Rooms are spacious and clean.

Reviewed on Jul 3, 2026

Mansión Alcázar Boutique Hotel

4 out of 5

Price was $441, price is now $296 per person

$296

per person

Aug 20 - Aug 23

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Francisco Plaza Market and San Sebastian Plaza are located nearby.

The property was stunning. From the minute that you enter to the time that you leave the service to the client was absolutely top notch. The young lady that assisted us was great. Overall 100000% recommend.

Reviewed on Jul 4, 2026

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5

Save 100% on your flight

Price was $614, price is now $420 per person

$420

per person

Aug 20 - Aug 23

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this luxury hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Save 100% on your flight

Price was $3,330, price is now $2,289 per person

$2,289

per person

Sep 18 - Sep 26

found 1 day ago

Roundtrip flight included

New York (JFK) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.

Reviewed on Oct 25, 2025

Santa Lucia House - Forum

4 out of 5

Price was $335, price is now $244 per person

$244

per person

Aug 20 - Aug 23

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Plaza Rotary Market and Civic Plaza are located nearby.

Everything was perfect in the property

Reviewed on Jul 3, 2026

Hotel El Conquistador

4 out of 5

Price was $335, price is now $247 per person

Price found within the past 48 hours. Click for updated prices.

Hotel Marcelius

3.5 out of 5

Kennedy

Price was $913, price is now $728 per person

$728

per person

Sep 10 - Sep 17

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Guayaquil (GYE)

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Las Peñas

Save 100% on your flight

Price was $2,870, price is now $1,808 per person

$1,808

per person

Sep 10 - Sep 17

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Guayaquil (GYE)