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Featured Panhandle Plains Family Hotels
Hawthorn Suites by Wyndham Lubbock
4435 Marsha Sharp Fwy, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Lubbock. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
MCM Elegante Suites Abilene
4250 Ridgemont Dr, Abilene, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Abilene. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Spark by Hilton Amarillo East
2301 East I40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Home2 Suites by Hilton Amarillo
8251 West Amarillo Blvd., Amarillo, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Studio 6 Amarillo, TX – West Medical Center
6801 W Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...
Ashmore Inn and Suites
4019 S Loop 289, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Drury Inn & Suites Amarillo
8540 W Interstate 40, Amarillo, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
MCM Eleganté Hotel & Suites
801 Avenue Q, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Country Inn & Suites by Radisson, Amarillo I-40 West, TX
2000 Soncy Road, Amarillo, TX
Fully refundable
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Embassy Suites Lubbock
5215 S Loop 289, Lubbock, TX
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the bar in our ...
Days Inn by Wyndham Amarillo East
1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Sleep Inn & Suites West Medical Center
6915 I-40 W, Amarillo, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Panhandle Plains
Studio 6 Amarillo, TX – West Medical Center
6801 W Interstate 40, Amarillo, TX
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...
7.4/10 Good! (1,010 reviews)
"Clean room, friendly environment!"
Reviewed on Oct 11, 2025
Home2 Suites by Hilton Amarillo
8251 West Amarillo Blvd., Amarillo, TX
Stay at this 3-star hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (1,001 reviews)
"Matt at the desk was kind and very helpful. Love that this is a pet friendly property."
Reviewed on Oct 5, 2025
Country Inn & Suites by Radisson, Amarillo I-40 West, TX
2000 Soncy Road, Amarillo, TX
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (2,377 reviews)
"Very nice hotel.A little hard to get to from the highway but my stay was pleasent. I had a problem with my tv and unfortunately the front desk had to call the maintenance guy to come back to work to fix it, after we he had already gone home. It took him 2 seconds to fix it and he was very nice. Had ..."
Reviewed on Oct 9, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Panhandle Plains
La Quinta Inn & Suites by Wyndham Lubbock West Medical Centr
4115 Marsha Sharp Freeway, Lubbock, TX
Stay at this 3-star business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Fairfield Inn & Suites by Marriott Amarillo Central
I-40 East, 1911, Amarillo, TX
Stay at this 3-star business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Spark by Hilton Amarillo East
2301 East I40, Amarillo, TX
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Panhandle Plains
- Hotels with a Pool in Panhandle Plains
- Pet-friendly Hotels in Panhandle Plains
- Hotels with an Indoor Pool in Panhandle Plains
- Hotels with Hot Tubs in Panhandle Plains
- Historic Hotels in Panhandle Plains
- Resorts & Hotels with Spas in Panhandle Plains
- Luxury Hotels in Panhandle Plains
- Winery Hotels in Panhandle Plains
- Apartment Hotel in Panhandle Plains
Panhandle Plains Neighborhoods
Top Points of Interests in Panhandle Plains
- Hotels near Texas Tech University
- Hotels near Sheppard Air Force Base
- Hotels near Possum Kingdom Lake
- Hotels near Palo Duro Canyon State Park
- Hotels near Palo Duro Canyon
- Hotels near Wichita Falls
- Hotels near Buddy Holly Center
- Hotels near Cadillac Ranch
- Hotels near University Medical Center
- Hotels near Abilene Christian University
- Hotels near Midwestern State University
- Hotels near American Quarter Horse Association
- Hotels near Dyess Air Force Base
- Hotels near Mall of Abilene
- Hotels near Hardin Simmons University
- Hotels near Abilene Zoo
- Hotels near Wonderland Amusement Park
- Hotels near Taylor County Expo Center
- Hotels near Covenant Lakeside Hospital
- Hotels near Kiowa Casino
Cities near Panhandle Plains
- Abilene Hotels (135.87 mi)
- Lawton Hotels (141.9 mi)
- Wichita Falls Hotels (135.35 mi)
- Weatherford Hotels (200.9 mi)
- Stephenville Hotels (203.98 mi)
- Hill Country Hotels (284.74 mi)
- Hobbs Hotels (167.65 mi)
- Brownwood Hotels (201.42 mi)
- Big Spring Hotels (138.94 mi)
- Canyon Hotels (82.33 mi)
- Sweetwater Hotels (121.2 mi)
- Mineral Wells Hotels (183.46 mi)
- Clovis Hotels (136.01 mi)
- Decatur Hotels (197.91 mi)
- Snyder Hotels (82.47 mi)
- Dalhart Hotels (160.17 mi)
- Childress Hotels (39.46 mi)
- Dumas Hotels (132.42 mi)
- Clayton Hotels (204.72 mi)
- Graford Hotels (172.17 mi)