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Hotels in Houston

Choose from 7819 Houston Hotel Deals

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
  • 9 min drive from MD Anderson Cancer Center
The price is $125 per night from Apr 6 to Apr 7
$125
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,156 reviews)
"Good hotel, we had a refurbed room. Good little bistro that did great breakfast. No self parking - we used a nearby public garage. Despite being one block from main street the area didn't exactly feel safe. The garages all had active security guards and there were many vagrants."

Reviewed on Mar 22, 2025

Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
  • 6 min drive from MD Anderson Cancer Center
The price is $169 per night from Apr 4 to Apr 5
$169
includes taxes & fees
Apr 4 - Apr 5
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,864 reviews)
"Our room was spacious and clean. The hotel overall was great and we will be returning."

Reviewed on Mar 22, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Sonesta Hotel Houston IAH Airport
Sonesta Hotel Houston IAH Airport
4 out of 5
425 North Sam Houston Parkway East, Houston, TX
  • 39 min drive from MD Anderson Cancer Center
The price is $83 per night from Mar 26 to Mar 27
$83
includes taxes & fees
Mar 26 - Mar 27
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
7.4/10 Good! (1,025 reviews)
"Pool wasn't clean, waterfall wasn't running. Bar closed at 10 pm every night so my friends couldn't get something when they got in. Sam's restaurant staff were very nice but front desk employees were not friendly."

Reviewed on Mar 23, 2025

Sonesta Hotel Houston IAH Airport
The Whitehall Houston
The Whitehall Houston
4 out of 5
1700 Smith St, Houston, TX
  • 8 min drive from MD Anderson Cancer Center
The price is $167 per night from Apr 6 to Apr 7
$167
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,295 reviews)
"Property is showing wear, John front desk was amazingly kind"

Reviewed on Mar 22, 2025

The Whitehall Houston
Hyatt Place Houston-North
Hyatt Place Houston-North
3.5 out of 5
300 Ronan Park Place, Houston, TX
  • 39 min drive from MD Anderson Cancer Center
The price is $80 per night from Apr 13 to Apr 14
$80
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
6.6/10 (919 reviews)
"If I ever come back to Texas definitely will stay At this hotel again"

Reviewed on Mar 22, 2025

Hyatt Place Houston-North
Holiday Inn Houston Downtown by IHG
Holiday Inn Houston Downtown by IHG
3 out of 5
1616 Main St, Houston, TX
  • 8 min drive from MD Anderson Cancer Center
The price is $139 per night from Apr 7 to Apr 8
$139
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,091 reviews)
"We had a fantastic stay! This was a great pick for us for location, convenience and also amenities! The free shuttle and breakfast was sooo appreciated. Wonderful and helpful staff! Highly recommend"

Reviewed on Mar 22, 2025

Holiday Inn Houston Downtown by IHG
Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
  • 12 min walk from MD Anderson Cancer Center
The price is $158 per night from Mar 30 to Mar 31
$158
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,177 reviews)
"The rooms were spotless and very clean. The fitness center was perfect too, they gave everything you need at this hotel."

Reviewed on Mar 21, 2025

Blossom Hotel Houston
The Royal Sonesta Houston Galleria
The Royal Sonesta Houston Galleria
4 out of 5
2222 West Loop South, Houston, TX
  • 6 min drive from MD Anderson Cancer Center
The price is $221 per night from Apr 11 to Apr 12
$221
includes taxes & fees
Apr 11 - Apr 12
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,021 reviews)
"10/10. The only place I’ll be staying from now on when I need a staycation away from home."

Reviewed on Mar 21, 2025

The Royal Sonesta Houston Galleria
Hyatt Regency Houston West
Hyatt Regency Houston West
3.5 out of 5
13210 Katy Fwy, Houston, TX
  • 14 min drive from MD Anderson Cancer Center
The price is $119 per night from Apr 6 to Apr 7
$119
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3.5-star business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.4/10 Very Good! (1,017 reviews)
"Inside the room mildew mold"

Reviewed on Mar 23, 2025

Hyatt Regency Houston West
Hilton Americas-Houston
Hilton Americas-Houston
4 out of 5
1600 Lamar Street, Houston, TX
  • 7 min drive from MD Anderson Cancer Center
The price is $210 per night from Apr 5 to Apr 6
$210
includes taxes & fees
Apr 5 - Apr 6
Stay at this 4-star spa hotel in Houston. Enjoy a full-service spa, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,208 reviews)
"Convenient to Discovery Green"

Reviewed on Mar 21, 2025

Hilton Americas-Houston
Heritage Inn & Suites The Woodlands, Trademark by Wyndham
Heritage Inn & Suites The Woodlands, Trademark by Wyndham
3 out of 5
28099 I 45 N, The Woodlands, TX
  • 1 hour drive from MD Anderson Cancer Center
The price is $109 per night from Mar 30 to Mar 31
$109
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in The Woodlands. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,188 reviews)
"Staff was friendly and helpful. Room was quiet and spacious and clean. I recommend this place based on easy access, great staff, good price point and clean."

Reviewed on Mar 24, 2025

Heritage Inn & Suites The Woodlands, Trademark by Wyndham
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4 out of 5
1100 Texas St, Houston, TX
  • 9 min drive from MD Anderson Cancer Center
The price is $145 per night from Mar 30 to Mar 31
$145
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,006 reviews)
"Great stay. Room service was awesome!"

Reviewed on Mar 21, 2025

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Book Last Minute Hotel Deals in Houston

Space shuttles aren’t the only thing to take off in Houston. This is a city meant for explorers, adventures, and the ones who say “no thank you” to conventional travel plans. It’s a place where you can rocket yourself as far as space and as deep as hidden art installations below the ground.

Ready to leave the others in the dust? Good. Whether you’re hitting up one of the hotels near Johnson Space Center or somewhere downtown, it’s time to plant your flag in this Texas town.

Make Your Own Mission

  • Uncover the Underground Scene: Literally. Go below the surface to the Buffalo Bayou Park Cistern, a former underground drinking water reservoir. The massive space has since turned into a trippy art installation with a 17-second echo. Prefer a more traditional underground scene? Knock twice on the red door for access into Last Concert Café, a quirky space for live jams, or unlock the oddities at Notsouh (but can you guess the bar’s namesake?).

  • Breakfast of Champions: Expect some funny looks if you’re not shoving breakfast tacos down your gullet every morning. Different day? Different taco joint. Bring those dolla’ bills to Tacos Tierra Caliente, where the breakfast tacos are a $1 a pop, or hit up the drive-thru at El Rey Taqueria, which gets bonus points for letting you order in your PJs. Make your home base one of the hotels in Downtown Houston and map out your taco hop from there.

  • Burp the Bayou: See that red button at Buffalo Bayou Park? Go on, push it. Just do it! We dare you. Under the Preston Street bridge, there’s an art installation known as the Big Bubble. We can’t tell you where exactly the button is—finding it is half the fun. What is it about mysterious red buttons that make them so irresistible? Find out for yourself and discover what the heck it means to burp the bayou.

  • Full of Bull: You can’t do Houston right without a rodeo. And the Houston Livestock Show and Rodeo isn’t just any ol’ rodeo; it’s the largest rodeo in the world. No bull. It’s three weeks of country music, barbecue contests, livestock shows, and a whole lot of cowboy boots.

It’s hard not to go big in a place like Houston, which means you’re definitely not going home yet. You can choose from hotels near Minute Maid Park—watch for fly balls!—or Houston hotels near the airport. Pick a Hotwire Hot Rate, it’s like clicking your own red button, and you’ll score the biggest last-minute hotel deals in Houston.