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Independent in Historic Route 66

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Featured Historic Route 66 Independent

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue, Chicago, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Chicago. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Congress Plaza Hotel
The New Pioneer

The New Pioneer

2.5 out of 5
2200 S Casino Dr, Laughlin, NV
Fully refundableReserve now, pay when you stay
Stay at this hotel in Laughlin. Enjoy free parking, a casino, and 2 bars/lounges. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
The New Pioneer
The Sage Hotel

The Sage Hotel

3 out of 5
725 Cerrillos Rd, Santa Fe, NM
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service, and a 24-hour fitness center. Our guests praise the breakfast and ...
The Sage Hotel
Chicago Club Inn & Suites

Chicago Club Inn & Suites

3 out of 5
630 Pasquinelli Dr, Westmont, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Westmont. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
Chicago Club Inn & Suites
Hotel Felix River North/Magnificent Mile

Hotel Felix River North/Magnificent Mile

4 out of 5
111 W Huron St, Chicago, IL
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Chicago. Enjoy breakfast (surcharge), a 24-hour health club, and valet parking (surcharge). Our guests praise the helpful ...
Hotel Felix River North/Magnificent Mile
Little America Flagstaff

Little America Flagstaff

4 out of 5
2515 E Butler Ave, Flagstaff, AZ
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Flagstaff. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the breakfast and the pool in ...
Little America Flagstaff
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
River Spirit Casino Resort

River Spirit Casino Resort

4 out of 5
8330 Riverside Parkway, Tulsa, OK
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa resort in Tulsa. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the helpful staff in our reviews. ...
River Spirit Casino Resort
University Plaza Hotel and Convention Center Springfield

University Plaza Hotel and Convention Center Springfield

3.5 out of 5
333 S John Q Hammons Pkwy, Springfield, MO
Fully refundable
Stay at this 3.5-star business-friendly hotel in Springfield. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
University Plaza Hotel and Convention Center Springfield
Avi Resort & Casino

Avi Resort & Casino

3.5 out of 5
10000 Aha Macav Pkwy, Laughlin, NV
Stay at this 3.5-star beach hotel in Laughlin. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
Avi Resort & Casino
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

4 out of 5
1301 N State Pkwy, Chicago, IL
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Chicago. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the helpful ...
The Chicago Hotel Collection Ambassador Gold Coast
Edgewater Hotel & Casino Resort

Edgewater Hotel & Casino Resort

3.5 out of 5
2020 S. Casino Drive, Laughlin, NV
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly resort in Laughlin. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the convenient ...
Edgewater Hotel & Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in Historic Route 66

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in Historic Route 66. What can you say? You like their style, they’re in a good part of Historic Route 66, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , Historic Route 66 to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in Historic Route 66 at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $49.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.