Search for Cheap Deals on
Hotels in Daufuskie Island

Check Last Minute Daufuskie Island Hotel Deals

Tonight Jun 14 - Jun 15Next weekend Jun 19 - Jun 21

Choose from 15554 Daufuskie Island Hotel Deals

Hotel Indigo Savannah Historic District by IHG

Hotel Indigo Savannah Historic District by IHG

4 out of 5
201 W Bay St Savannah GA
  • 29 min drive from Daufuskie Island Beach
Book a stay at this business-friendly hotel in Savannah. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8/10 Very Good! (2,166 reviews)
"Spacious clean rooms and helpful and friendly staff. Location is premium next to all the restaurants and shopping."

Reviewed on Jun 13, 2026

Hotel Indigo Savannah Historic District by IHG
Hyatt Regency Savannah

Hyatt Regency Savannah

4 out of 5
2 W Bay St Savannah GA
  • 29 min drive from Daufuskie Island Beach
Book a stay at this business-friendly hotel in Savannah. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (3,726 reviews)
"Room war very clean! Staff was very nice and helpful. Breakfast was great."

Reviewed on Jun 14, 2026

Hyatt Regency Savannah
Beach House Resort Hilton Head

Beach House Resort Hilton Head

4 out of 5
1 South Forest Beach Drive Hilton Head Island SC
  • 18 min drive from Daufuskie Island Beach
Book a stay at this beach hotel in Hilton Head Island. Enjoy free WiFi, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
8.8/10 Excellent! (1,277 reviews)
"The resort had a location that can't be beat, near the center of the island and walkable to restaurants, shopping, and the beach. It was clean but worn (most hotels along the water will be). It's hard to keep the humidity out but the room gave it a darn good try. We fell for the upsell of renting ..."

Reviewed on Jun 13, 2026

Beach House Resort Hilton Head
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

4.5 out of 5
1 Hotel Circle Hilton Head Island SC
  • 24 min drive from Daufuskie Island Beach
Book a stay at this luxury resort in Hilton Head Island. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,547 reviews)
"Awesome stay Nice and clean"

Reviewed on Jun 13, 2026

Hilton Beachfront Resort & Spa Hilton Head Island
The DeSoto

The DeSoto

4 out of 5
15 East Liberty Street Savannah GA
  • 29 min drive from Daufuskie Island Beach
Book a stay at this business-friendly hotel in Savannah. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the restaurant and the helpful ...
8.8/10 Excellent! (3,042 reviews)
"The location is great and the staff were amazing. On the downside, no refrigerator in the room."

Reviewed on Jun 13, 2026

The DeSoto
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

4 out of 5
130 Shipyard Drive Hilton Head Island SC
  • 22 min drive from Daufuskie Island Beach
Book a stay at this beach hotel in Hilton Head Island. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful ...
8.8/10 Excellent! (1,384 reviews)
"We had such a wonderful stay at Sonesta Resort Hilton Head Island! We’ve been coming to Hilton Head for over 20 years. We’ve stayed all over the island but really love Sonesta.The property itself is absolutely beautiful and so well maintained. From the gorgeous grounds to the spa-like adult pool ..."

Reviewed on Jun 12, 2026

Sonesta Resort Hilton Head Island
River Street Inn

River Street Inn

4 out of 5
124 E. Bay Street Savannah GA
  • 29 min drive from Daufuskie Island Beach
Book a stay at this luxury hotel in Savannah. Enjoy free WiFi, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the convenient parking ...
9.2/10 Wonderful! (1,938 reviews)
"Always the best stay! The generous Manager’s reception makes this place stand out!"

Reviewed on Jun 14, 2026

River Street Inn
Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

2.5 out of 5
10 Tanglewood Drive Hilton Head Island SC
  • 18 min drive from Daufuskie Island Beach
Book a stay at this business-friendly hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and ...
8.4/10 Very Good! (575 reviews)
"Clean, comfy room walking distance from everything we wanted to do. Staff was very sweet. I was confused by the listing on here saying, "Free buffet breakfast on weekend mornings"--we were only here M-F, and there was a nice free breakfast every day."

Reviewed on Jun 12, 2026

Holiday Inn Express Hilton Head Island by IHG
Palmera Inn and Suites

Palmera Inn and Suites

3 out of 5
12 Park Ln Hilton Head Island SC
  • 21 min drive from Daufuskie Island Beach
Stay at this hotel in Hilton Head Island. Enjoy free breakfast, an outdoor pool, and a fitness center. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,375 reviews)
"Nice pool and spa!! Clean room! Helpful staff!!"

Reviewed on Jun 14, 2026

Palmera Inn and Suites
Marriott Savannah Riverfront

Marriott Savannah Riverfront

4 out of 5
100 General Mcintosh Blvd Savannah GA
  • 28 min drive from Daufuskie Island Beach
Book a stay at this spa hotel in Savannah. Enjoy a full-service spa, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,226 reviews)
"Over all the property is deserving of a rating of maybe 4/5. The room and bathroom were clean, staff was very helpful and the room service ordered meals were promptly delivered in take out plastic bags however the expectation of the hotel was somewhat disappointing. The pool was disgusting!"

Reviewed on Jun 12, 2026

Marriott Savannah Riverfront
Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort

4 out of 5
23 Ocean Lane Hilton Head Island SC
  • 23 min drive from Daufuskie Island Beach
Book a stay at this beach resort in Hilton Head Island. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (1,003 reviews)
"It was nice but you can do better"

Reviewed on Jun 10, 2026

Omni Hilton Head Oceanfront Resort
JW Marriott Savannah Plant Riverside District

JW Marriott Savannah Plant Riverside District

5 out of 5
400 W RIVER ST Savannah GA
  • 29 min drive from Daufuskie Island Beach
Book a stay at this luxury hotel in Savannah. Enjoy free WiFi, a full-service spa, and 12 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,601 reviews)
"Wonderful!!!!"

Reviewed on Jun 12, 2026

JW Marriott Savannah Plant Riverside District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Daufuskie Island

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Daufuskie Island hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Daufuskie Island.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Daufuskie Island’s 15,554 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $156. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Daufuskie Island hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Daufuskie Island. No matter your reason for visiting Daufuskie Island, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Daufuskie Island hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Daufuskie Island for as low as $156.

How many hotels are there in Daufuskie Island?

With over 15,554 hotels in Daufuskie Island, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $156.

How to find cheap car rentals in Daufuskie Island?

Finding a cheap car rental deal in Daufuskie Island is as easy as scoring cheap hotels in Daufuskie Island. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.