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Hotels in Saint Helena Island

Choose from 12817 Saint Helena Island Hotel Deals

Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

4 out of 5
130 Shipyard Drive Hilton Head Island SC
  • 43 min drive from Penn Center
Book a stay at this beach hotel in Hilton Head Island. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful ...
8.6/10 Excellent! (1,228 reviews)
Everything about my stay was great...very clean, upscale rooms, friendly and helpful staff. I really enjoyed it.

Reviewed on Jan 31, 2026

Sonesta Resort Hilton Head Island
Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort

4 out of 5
23 Ocean Lane Hilton Head Island SC
  • 41 min drive from Penn Center
Book a stay at this beach resort in Hilton Head Island. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (1,000 reviews)
Everything has been wonderful

Reviewed on Jan 24, 2026

Omni Hilton Head Oceanfront Resort
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

4.5 out of 5
1 Hotel Circle Hilton Head Island SC
  • 40 min drive from Penn Center
Book a stay at this luxury resort in Hilton Head Island. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,413 reviews)
Our room was very comfortable and clean. We had an ocean view room and it was amazing looking out at the sunrise and sunset. The desk staff were very warm and friendly and knowledgeable. The valet staff was excellent, especially Joey and Charles.

Reviewed on Jan 24, 2026

Hilton Beachfront Resort & Spa Hilton Head Island
Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

2.5 out of 5
10 Tanglewood Drive Hilton Head Island SC
  • 45 min drive from Penn Center
Book a stay at this business-friendly hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and ...
8.4/10 Very Good! (397 reviews)
Nice staff. Clean. Great breakfast

Reviewed on Feb 1, 2026

Holiday Inn Express Hilton Head Island by IHG
Palmera Inn and Suites

Palmera Inn and Suites

3 out of 5
12 Park Ln Hilton Head Island SC
  • 42 min drive from Penn Center
Stay at this hotel in Hilton Head Island. Enjoy free breakfast, a fitness center, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,200 reviews)
.

Reviewed on Feb 1, 2026

Palmera Inn and Suites
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

4 out of 5
2 Grasslawn Ave Hilton Head Island SC
  • 32 min drive from Penn Center
Book a stay at this beach hotel in Hilton Head Island. Enjoy 3 outdoor pools, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,002 reviews)
clean. nice layout

Reviewed on Jan 29, 2026

The Westin Hilton Head Island Resort & Spa
Beach House Resort Hilton Head

Beach House Resort Hilton Head

4 out of 5
1 South Forest Beach Drive Hilton Head Island SC
  • 46 min drive from Penn Center
Book a stay at this beach hotel in Hilton Head Island. Enjoy free WiFi, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,048 reviews)
This beautiful, relaxing and well appointed one bedroom apartment in Bimini was the perfect stay for my week of diving and exploring here. Upon arrival, it was spotless and welcoming, with what appears to be all new fixtures, appliances, bedding, towels, ample kitchen supplies and furniture. The ...

Reviewed on Jan 30, 2026

Beach House Resort Hilton Head
Coral Sands Resorts by Palmera

Coral Sands Resorts by Palmera

3.5 out of 5
66 Pope Avenue Hilton Head Island SC
  • 45 min drive from Penn Center
Book a stay at this golf aparthotel in Hilton Head Island. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff ...
9.4/10 Exceptional! (869 reviews)
Favorite place to stay when in Hilton Head. Convenient to everything we enjoy.

Reviewed on Nov 17, 2025

Coral Sands Resorts by Palmera
Montage Palmetto Bluff

Montage Palmetto Bluff

5 out of 5
477 Mount Pelia Road Bluffton SC
  • 45 min drive from Penn Center
Book a stay at this luxury hotel in Bluffton. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (261 reviews)
Return trip for us! We absolutely love it! The hotel, restaurants and grounds are so well maintained.

Reviewed on Jan 24, 2026

Montage Palmetto Bluff
Hampton Inn Hilton Head

Hampton Inn Hilton Head

2.5 out of 5
1 Dillon Road Hilton Head Island SC
  • 32 min drive from Penn Center
Book a stay at this golf hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,003 reviews)
The room was spotless. The staff was very courteous and the breakfast was enjoyable. Will probably come back for another solo trip.

Reviewed on Jan 25, 2026

Hampton Inn Hilton Head
Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head

3 out of 5
1575 Fording Island Rd Hilton Head Island SC
  • 35 min drive from Penn Center
Stay at this hotel in Hilton Head Island. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,001 reviews)
The room was clean and the staff friendly. Only negative was the renovation noise which -of course- couldnt be helped 😊

Reviewed on Jan 29, 2026

Hilton Garden Inn Hilton Head
Spark By Hilton Hilton Head Island

Spark By Hilton Hilton Head Island

3 out of 5
11 Lemoyne Avenue Hilton Head Island SC
  • 46 min drive from Penn Center
Book a stay at this business-friendly hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
8.2/10 Very Good! (563 reviews)
Room was very clean and orderly, Staff was pleasant and helpful.

Reviewed on Jan 24, 2026

Spark By Hilton Hilton Head Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Saint Helena Island

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Saint Helena Island.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Saint Helena Island’s 12,817 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $87. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Saint Helena Island hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Saint Helena Island. No matter your reason for visiting Saint Helena Island, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Saint Helena Island hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Saint Helena Island?

With over 12,817 hotels in Saint Helena Island, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $87.

How to find cheap car rentals in Saint Helena Island?

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