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Hotels in Ladys Island

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Choose from 12289 Ladys Island Hotel Deals

Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort

4 out of 5
23 Ocean Lane Hilton Head Island SC
  • 54 min drive from Coosaw Island
Book a stay at this beach resort in Hilton Head Island. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
The room was great. The staff was friendly. Paulette made sure we had a great stay

Reviewed on Dec 7, 2025

Omni Hilton Head Oceanfront Resort
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

4.5 out of 5
1 Hotel Circle Hilton Head Island SC
  • 53 min drive from Coosaw Island
Book a stay at this luxury resort in Hilton Head Island. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,390 reviews)
Nice view of the beach

Reviewed on Dec 8, 2025

Hilton Beachfront Resort & Spa Hilton Head Island
Palmera Inn and Suites

Palmera Inn and Suites

3 out of 5
12 Park Ln Hilton Head Island SC
  • 54 min drive from Coosaw Island
Stay at this hotel in Hilton Head Island. Enjoy free breakfast, a fitness center, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,159 reviews)
The room was very clean and spacious! The walls are thin. You can hear doors shutting and people talking in the hallways, but at night it was quiet so that wasn’t a problem. We only stayed for one night and did not eat breakfast so I can’t review that part, but I would stay here again.

Reviewed on Dec 4, 2025

Palmera Inn and Suites
Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

2.5 out of 5
10 Tanglewood Drive Hilton Head Island SC
  • 58 min drive from Coosaw Island
Book a stay at this business-friendly hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and ...
8.2/10 Very Good! (332 reviews)
Yes

Reviewed on Dec 6, 2025

Holiday Inn Express Hilton Head Island by IHG
Beach House Resort Hilton Head

Beach House Resort Hilton Head

4 out of 5
1 South Forest Beach Drive Hilton Head Island SC
  • 58 min drive from Coosaw Island
Book a stay at this beach hotel in Hilton Head Island. Enjoy free WiFi, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (995 reviews)
The room was very clean. The ocean view was fantastic. The staff was friendly and courteous.

Reviewed on Dec 7, 2025

Beach House Resort Hilton Head
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

4 out of 5
130 Shipyard Drive Hilton Head Island SC
  • 56 min drive from Coosaw Island
Book a stay at this beach hotel in Hilton Head Island. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful ...
8.6/10 Excellent! (1,176 reviews)
Beautiful area and the hotel staff were so friendly. Would love to stay for several days!

Reviewed on Dec 3, 2025

Sonesta Resort Hilton Head Island
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

4 out of 5
2 Grasslawn Ave Hilton Head Island SC
  • 45 min drive from Coosaw Island
Book a stay at this beach hotel in Hilton Head Island. Enjoy 3 outdoor pools, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,002 reviews)
great staff

Reviewed on Dec 1, 2025

The Westin Hilton Head Island Resort & Spa
Hampton Inn Hilton Head

Hampton Inn Hilton Head

2.5 out of 5
1 Dillon Road Hilton Head Island SC
  • 45 min drive from Coosaw Island
Book a stay at this golf hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,002 reviews)
Nice staff, clean room, tasty food

Reviewed on Dec 1, 2025

Hampton Inn Hilton Head
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

2.5 out of 5
3662 Trask Parkway Beaufort SC
  • 13 min drive from Coosaw Island
Book a stay at this business-friendly hotel in Beaufort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (697 reviews)
Amazing

Reviewed on Nov 29, 2025

Tru by Hilton Beaufort, SC
Spark By Hilton Hilton Head Island

Spark By Hilton Hilton Head Island

3 out of 5
11 Lemoyne Avenue Hilton Head Island SC
  • 59 min drive from Coosaw Island
Book a stay at this business-friendly hotel in Hilton Head Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
8.2/10 Very Good! (529 reviews)
No beach view

Reviewed on Dec 9, 2025

Spark By Hilton Hilton Head Island
Best Western Point South

Best Western Point South

2.5 out of 5
3536 Point South Drive Yemassee SC
  • 33 min drive from Coosaw Island
Book a stay at this business-friendly hotel in Yemassee. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,002 reviews)
Very clean

Reviewed on Dec 6, 2025

Best Western Point South
Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head

3 out of 5
1575 Fording Island Rd Hilton Head Island SC
  • 45 min drive from Coosaw Island
Stay at this hotel in Hilton Head Island. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,006 reviews)
Quiet. Not the cleanest, not terrible, but easy fixes. “Lots” of hair in the bathroom, espec on the “ceiling”…of all places!! Outlets are dirty and broken.

Reviewed on Dec 7, 2025

Hilton Garden Inn Hilton Head
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Ladys Island

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Ladys Island.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Ladys Island’s 12,289 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $92. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Ladys Island hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Ladys Island. No matter your reason for visiting Ladys Island, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Ladys Island hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Ladys Island for as low as $92.

How many hotels are there in Ladys Island?

With over 12,289 hotels in Ladys Island, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $92.

How to find cheap car rentals in Ladys Island?

Finding a cheap car rental deal in Ladys Island is as easy as scoring cheap hotels in Ladys Island. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.