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Hotels in Otay Mesa

See all 1,219 Properties in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa

2296 Niels Bohr Ct, San Diego
    2.5 out of 5.0
     
     

    Located in Otay Mesa, this hotel is within 6 mi (10 km) of Autonomous University of Baja California Tijuana, U.S. Consulate General Tijuana, and Aquatica. Mattress ...

    Holiday Inn Express Hotel & Suites San Diego Otay Mesa$71

    Holiday Inn Express Hotel & Suites San Diego Otay Mesa$71
    Quality Suites San Diego Otay Mesa

    Quality Suites San Diego Otay Mesa

    2351 Otay Center Dr, San Diego
      2.5 out of 5.0
       
       

      This hotel is in southern San Diego, within a mile of the Mexican border and Tijuana. Knott’s Soak City and Cricket Wireless Amphitheater are within six ...

      Quality Suites San Diego Otay Mesa$89

      Quality Suites San Diego Otay Mesa$89
      The Sofia Hotel

      The Sofia Hotel

      150 W Broadway, San Diego
        3.5 out of 5.0
         
         

        In the heart of downtown San Diego, this historic boutique hotel is 2 blocks from Horton Plaza, 4 blocks from the Gaslamp Quarter, and 6 blocks from the San ...

        The Sofia Hotel$113

        The Sofia Hotel$113
        Best Western Seven Seas

        Best Western Seven Seas

        411 Hotel Circle South, San Diego
          3.0 out of 5.0
           
           

          Adjacent to I-8, this budget-friendly hotel is within 6 miles of 2 sports stadiums, the Gaslamp Quarter, the convention center, the San Diego Zoo, SeaWorld, ...

          Best Western Seven Seas$65

          Best Western Seven Seas$65
          Town and Country San Diego

          Town and Country San Diego

          500 Hotel Circle North, San Diego
            3.5 out of 5.0
             
             

            Comprising 32 acres, this resort and conference center is next to the 27-hole Riverwalk Golf Club; Old Town, Balboa Park, SeaWorld San Diego, and the world famous ...

            Town and Country San Diego$97

            Town and Country San Diego$97
            Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld

            Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld

            543 Hotel Circle S, San Diego
              3.0 out of 5.0
               
               

              Located in San Diego's Mission Valley corridor just off I-8, this San Diego hotel is a half-mile from 2 shopping centers, and within 5 miles of SeaWorld, downtown, ...

              Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld$67

              Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld$67
              Hard Rock Hotel San Diego

              Hard Rock Hotel San Diego

              207 5th Ave, San Diego
                4.0 out of 5.0
                 
                 

                The Hard Rock Hotel is in the center of San Diego's bustling Gaslamp Quarter, with restaurants, bars, and nightlife. The San Diego Convention Center is across ...

                Hard Rock Hotel San Diego$113

                Hard Rock Hotel San Diego$113
                Paradise Point Resort & Spa

                Paradise Point Resort & Spa

                1404 Vacation Rd, San Diego
                  4.0 out of 5.0
                   
                   

                  Paradise Point Resort & Spa is on a private tropical island in San Diego’s Mission Bay. SeaWorld® is a 4-minute drive away over Mission Bay’s South Cove, and ...

                  Paradise Point Resort & Spa$153

                  Paradise Point Resort & Spa$153
                  Wyndham San Diego Bayside

                  Wyndham San Diego Bayside

                  1355 N Harbor Drive, San Diego
                    4.0 out of 5.0
                     
                     

                    Just west of the downtown core, this San Diego hotel is across the street from the cruise ship terminal, Coronado ferry, and the Maritime Museum. The Gaslamp ...

                    Wyndham San Diego Bayside$114

                    Wyndham San Diego Bayside$114
                    Riverleaf Inn Mission Valley

                    Riverleaf Inn Mission Valley

                    2484 Hotel Circle Place, San Diego
                      2.5 out of 5.0
                       
                       

                      Located in Mission Valley, this motel is within 1 mi (2 km) of Presidio Park and Old Town San Diego State Park. University of San Diego and SeaWorld are also ...

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                      Otay Mesa Hotel Guide

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