Search for Cheap Deals onBest Western in Otay Mesa West
Photo by Leonardo De Leon
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured Otay Mesa West Best Western

Best Western Seven Seas
411 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

Best Western Yacht Harbor Hotel
5005 N Harbor Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...

Best Western Chula Vista/Otay Valley Hotel
4450 Main Street, Chula Vista, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Chula Vista. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Best Western Americana Inn
815 W San Ysidro Boulevard, San Ysidro, CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Ysidro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...

Best Western San Diego Pacific Beach/Mission Bay
2575 Clairemont Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the helpful ...

Best Western Downtown San Diego
840 A Street, San Diego, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and parking (surcharge). Our guests praise the helpful staff in ...

Best Western Santee Lodge
10726 Woodside Ave, Santee, CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
- Top Hotels by Star Rating
- More Hotel Types
- Popular Attractions
- Other Brands
- Popular Neighborhoods
- Nearby Cities
More Hotel Options in Otay Mesa West
Top Points of Interests in Otay Mesa West
- Hotels near San Diego Zoo (12.29 mi)
- Hotels near San Diego Convention Center (10.87 mi)
- Hotels near Mission Bay (17.06 mi)
- Hotels near San Ysidro Border Crossing (2.74 mi)
- Hotels near Petco Park (10.76 mi)
- Hotels near Mission Beach (17.63 mi)
- Hotels near Balboa Park (11.88 mi)
- Hotels near San Diego State University (13.58 mi)
- Hotels near Hotel Circle (14.43 mi)
- Hotels near Naval Base San Diego (7.94 mi)
- Hotels near Port of San Diego (11.85 mi)
- Hotels near USS Midway Museum (11.73 mi)
- Hotels near Marine Corps Recruit Depot (13.97 mi)
- Hotels near Hotel del Coronado (10.11 mi)
- Hotels near University of San Diego (15.6 mi)
- Hotels near Coronado Beach (10.63 mi)
- Hotels near Naval Base Coronado (12.2 mi)
- Hotels near Seaport Village (11.3 mi)
- Hotels near Las Americas Premium Outlets (2.43 mi)
- Hotels near B Street Cruise Ship Terminal (11.92 mi)
Top Neighborhoods in Otay Mesa West
- San Diego Hotels (11.38 mi)
- La Jolla Hotels (21.67 mi)
- Chula Vista Hotels (4.65 mi)
- Coronado Hotels (10.58 mi)
- Playas de Rosarito Hotels (24.36 mi)
- Rosarito Hotels (14.61 mi)
- El Cajon Hotels (15.92 mi)
- Coronado Island Hotels (11.64 mi)
- National City Hotels (7.41 mi)
- Southern California Hotels (89.06 mi)
- La Mesa Hotels (13.26 mi)
- San Ysidro Hotels (1.89 mi)
- Imperial Beach Hotels (3.44 mi)
- Alpine Hotels (24.41 mi)
- Santee Hotels (18.61 mi)
- Spring Valley Hotels (11.99 mi)
- Lakeside Hotels (20.78 mi)
- Bonita Hotels (5.68 mi)
- Jamul Hotels (14.15 mi)
- Lemon Grove Hotels (11.47 mi)
