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Featured Clayton Independent
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Forest Park Hotel by MDR
5915 Wilson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
The Cheshire
6300 Clayton Rd, Richmond Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
The West End
4215 Lindell Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions St. Louis Union Station and Busch Stadium ...
Casino Queen Hotel
200 Front Street, East St. Louis, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in East St. Louis. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean ...
Relax Inn Saint Charles
3800 Harry S Truman Blvd, St. Charles, MO
Fully refundable
Stay at this motel in St. Charles. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
Moonrise Hotel
6177 Delmar Blvd, St. Louis, MO
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
The Wildwood Hotel
2801 Fountain Pl, Wildwood, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
The Knight Center at Washington University
Throop Drive and Snow Way, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
The Last Hotel
1501 Washington Ave, St. Louis, MO
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Principal Hotel
310 S Main St, Columbia, IL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Triple Lakes Golf Course and Eckert’s Millstadt ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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- Historic Hotels in Clayton
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- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
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- Hotels with an Indoor Pool in Clayton
Top Points of Interests in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near Westport Plaza (7.79 mi)
- Hotels near St Charles Convention Center (12.99 mi)
- Hotels near Hollywood Casino (11.47 mi)
Top Neighborhoods in Clayton
- St. Charles Hotels (13.73 mi)
- Chesterfield Hotels (13.04 mi)
- Maryland Heights Hotels (7.51 mi)
- O'Fallon Hotels (22.54 mi)
- Fairview Heights Hotels (17.13 mi)
- St. Peters Hotels (19 mi)
- O'Fallon Hotels (23.35 mi)
- Brentwood Hotels (2.21 mi)
- Fenton Hotels (11.04 mi)
- Alton Hotels (18.7 mi)
- Collinsville Hotels (18.31 mi)
- Edwardsville Hotels (21.4 mi)
- Eureka Hotels (19.05 mi)
- Kirkwood Hotels (6.06 mi)
- Bridgeton Hotels (9.81 mi)
- Arnold Hotels (14.77 mi)
- Richmond Heights Hotels (0.98 mi)
- Belleville Hotels (20.19 mi)
- Southern Illinois Hotels (82.5 mi)
- Ozarks Hotels (156.82 mi)