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Hotels in Seneca

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Last Minute Hot Rate® Hotel Deals in Seneca

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Choose from 1509 Seneca Hotel Deals

Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
2 out of 5
1007 George Smith Mill Rd, Anderson, SC
  • 43 min drive from Keowee Reservoir
The price is $59 per night from May 16 to May 17
$59
per night
May 16 - May 17
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (708 reviews)
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Reviewed on May 7, 2024

Days Inn by Wyndham Anderson
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $109 per night from May 12 to May 13
$109
per night
May 12 - May 13
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (594 reviews)
"The best pet friendly hotel we have stayed at in a long time. The rooms are spacious and clean. I chose one with a full kitchen and it was equipped with everything i needed. Everywhere we walked the dogs was pristine. We did not see one bit of dog poop anywhere on the property. Awesome place."

Reviewed on May 8, 2024

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $107 per night from May 31 to Jun 1
$107
per night
May 31 - Jun 1
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (566 reviews)
"Clean and comfortable. Seems newer than some of the other Clemson area properties. Good water pressure and updated bathroom. Allows dogs and seems walkable to Death Valley. Across the street from Clemsons rec area by the lake."

Reviewed on Apr 28, 2024

Tru by Hilton Seneca Clemson
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
  • 14 min drive from Keowee Reservoir
The price is $71 per night from May 30 to May 31
$71
per night
May 30 - May 31
Book a stay at this business-friendly motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (597 reviews)
"Excellent front desk service. Nice and clean room, small but had everything needed. Property kept in good condition. Fresh coffee always available. Safe area"

Reviewed on Apr 21, 2024

Days Inn by Wyndham Seneca / Clemson Area
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $89 per night from Jun 6 to Jun 7
$89
per night
Jun 6 - Jun 7
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
7.8/10 Good! (478 reviews)
"House keeping is extremely nice and excellent ,"

Reviewed on Apr 30, 2024

Quality Inn Seneca US-123
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
  • 7 min drive from Keowee Reservoir
The price is $114 per night from May 19 to May 20
$114
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (512 reviews)
"Lovely hotel. Front desk was very helpful. Rooms clean. Some reviews indicated the beds were uncomfortable. They are on the “firm” side but then that’s my preference. Many options for breakfast."

Reviewed on Apr 18, 2024

Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $129 per night from May 20 to May 21
$129
per night
May 20 - May 21
Book a stay at this business-friendly hotel in Seneca. Enjoy free parking, a fitness center, and a 24-hour front desk. Our guests praise the breakfast and the ...
9.4/10 Exceptional! (101 reviews)
"Quite and clean"

Reviewed on May 3, 2024

Fairfield Inn & Suites Seneca Clemson Univ Area
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Keowee Reservoir
The price is $169 per night from May 12 to May 13
$169
per night
May 12 - May 13
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.8/10 Exceptional! (266 reviews)
"Excellent service, beautiful property!"

Reviewed on May 6, 2024

The Shepherd Hotel Downtown Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $99 per night from May 12 to May 13
$99
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,003 reviews)
been there done that
"went down to pick up my daughter from college! Have stayed there before. Hotel meets all basic needs, friendly helpful staff and can’t beat the price!! Stayed three nights so i could’ve use a pool!!"

Reviewed on May 8, 2024

Inn @ Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $101 per night from Jun 11 to Jun 12
$101
per night
Jun 11 - Jun 12
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (777 reviews)
"Great service. Need better fitness center."

Reviewed on May 3, 2024

Best Western Plus Clemson Hotel & Conference Center
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 17 min drive from Keowee Reservoir
The price is $129 per night from May 16 to May 17
$129
per night
May 16 - May 17
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (777 reviews)
"The staff is very friendly. Check in was fast and easy, room was clean with a big TV and nice air conditioning. The breakfast was organized and easy to access as well. Would definitely stay here again if I'm ever in the area."

Reviewed on May 7, 2024

Holiday Inn Express & Suites Clemson, an IHG Hotel
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3 out of 5
240 Madren Center Drive, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $149 per night from May 12 to May 13
$149
per night
May 12 - May 13
Stay at this 3-star golf hotel in Clemson. Enjoy free WiFi, an outdoor pool, and a golf course. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (725 reviews)
"Favorite place to stay in Clemson! The staff are very friendly and the grounds are beautiful! I can’t wait until our next stay!"

Reviewed on Apr 29, 2024

Clemson University's James F. Martin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Seneca

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Seneca hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Seneca.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Seneca’s 1,509 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Seneca hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Seneca. No matter your reason for visiting Seneca, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Seneca hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Seneca for as low as $59.

How many hotels are there in Seneca?

With over 1,509 hotels in Seneca, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Seneca?

Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Seneca now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Seneca right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.