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Seneca

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Seneca Flights as Low as $138

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Allegiant Air
Fri, Oct 16 - Mon, Oct 19
FLL
Fort Lauderdale - Hollywood Intl.
GSP
Greenville-Spartanburg Intl.
$138 Roundtrip, found 1 day ago
$138
Roundtrip
found 1 day ago
Select Allegiant Air flight, departing Fri, Oct 16 from Fort Lauderdale - Hollywood Intl. to Greenville-Spartanburg Intl., returning Mon, Oct 19, priced at $138 found 1 day ago
Allegiant Air
Sun, Oct 18 - Sun, Oct 25
SRQ
Sarasota-Bradenton Intl.
GSP
Greenville-Spartanburg Intl.
$160 Roundtrip, found 1 day ago
$160
Roundtrip
found 1 day ago
Select Allegiant Air flight, departing Sun, Oct 18 from Sarasota-Bradenton Intl. to Greenville-Spartanburg Intl., returning Sun, Oct 25, priced at $160 found 1 day ago
American Airlines
Mon, Nov 9 - Sat, Nov 14
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$180 Roundtrip, found 19 hours ago
$180
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Mon, Nov 9 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Nov 14, priced at $180 found 19 hours ago
Southwest Airlines
Wed, Oct 28 - Fri, Nov 13
BWI
Baltimore Washington Intl. Thurgood Marshall
GSP
Greenville-Spartanburg Intl.
$188 Roundtrip, found 2 days ago
$188
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Oct 28 from Baltimore Washington Intl. Thurgood Marshall to Greenville-Spartanburg Intl., returning Fri, Nov 13, priced at $188 found 2 days ago
Bargain Flight
Wed, Oct 7 - Tue, Oct 20
CLE
Hopkins Intl.
GSP
Greenville-Spartanburg Intl.
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, Oct 7 from Hopkins Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 20, priced at $246 found 1 day ago
Delta
Mon, Dec 14 - Thu, Dec 17
BOS
Logan Intl.
GSP
Greenville-Spartanburg Intl.
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Dec 14 from Logan Intl. to Greenville-Spartanburg Intl., returning Thu, Dec 17, priced at $253 found 3 days ago
Delta
Thu, Nov 26 - Wed, Dec 2
MSP
Minneapolis - St. Paul Intl.
GSP
Greenville-Spartanburg Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 26 from Minneapolis - St. Paul Intl. to Greenville-Spartanburg Intl., returning Wed, Dec 2, priced at $259 found 1 day ago
American Airlines
Tue, Dec 1 - Mon, Dec 21
IND
Indianapolis Intl.
GSP
Greenville-Spartanburg Intl.
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 1 from Indianapolis Intl. to Greenville-Spartanburg Intl., returning Mon, Dec 21, priced at $279 found 1 day ago
Bargain Flight
Tue, Mar 2 - Tue, Mar 9
LAS
Harry Reid Intl.
GSP
Greenville-Spartanburg Intl.
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Mar 2 from Harry Reid Intl. to Greenville-Spartanburg Intl., returning Tue, Mar 9, priced at $296 found 1 day ago
Bargain Flight
Tue, Oct 27 - Tue, Nov 3
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$306 Roundtrip, found 1 day ago
$306
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Oct 27 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Nov 3, priced at $306 found 1 day ago
Bargain Flight
Tue, Oct 6 - Sat, Oct 10
DFW
Dallas-Fort Worth Intl.
GSP
Greenville-Spartanburg Intl.
$312 Roundtrip, found 1 day ago
$312
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Oct 6 from Dallas-Fort Worth Intl. to Greenville-Spartanburg Intl., returning Sat, Oct 10, priced at $312 found 1 day ago
Southwest Airlines
Wed, Nov 11 - Tue, Nov 17
DAL
Love Field
GSP
Greenville-Spartanburg Intl.
$321 Roundtrip, found 22 hours ago
$321
Roundtrip
found 22 hours ago
Select Southwest Airlines flight, departing Wed, Nov 11 from Love Field to Greenville-Spartanburg Intl., returning Tue, Nov 17, priced at $321 found 22 hours ago
United
Thu, Nov 19 - Fri, Dec 4
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$334 Roundtrip, found 4 hours ago
$334
Roundtrip
found 4 hours ago
Select United flight, departing Thu, Nov 19 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Fri, Dec 4, priced at $334 found 4 hours ago
Delta
Fri, Nov 27 - Tue, Dec 8
IAH
George Bush Intercontinental
GSP
Greenville-Spartanburg Intl.
$339 Roundtrip, found 1 hour ago
$339
Roundtrip
found 1 hour ago
Select Delta flight, departing Fri, Nov 27 from George Bush Intercontinental to Greenville-Spartanburg Intl., returning Tue, Dec 8, priced at $339 found 1 hour ago
Bargain Flight
Mon, Sep 28 - Sat, Oct 3
ATL
Hartsfield-Jackson Atlanta Intl.
GSP
Greenville-Spartanburg Intl.
$342 Roundtrip, found 1 day ago
$342
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Mon, Sep 28 from Hartsfield-Jackson Atlanta Intl. to Greenville-Spartanburg Intl., returning Sat, Oct 3, priced at $342 found 1 day ago
Bargain Flight
Mon, Oct 5 - Tue, Oct 6
LAX
Los Angeles Intl.
GSP
Greenville-Spartanburg Intl.
$356 Roundtrip, found 1 day ago
$356
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Mon, Oct 5 from Los Angeles Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 6, priced at $356 found 1 day ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 10 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $138, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $138 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$138

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,005 reviews)
"Great location. Amenities were spot on restaurant staff excellent!"

Reviewed on Sep 23, 2026

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Lakeside Lodge Clemson
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreation Area and Cross Creek Plantation Golf ...
Get rates
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (754 reviews)
"One of the cleanest room I’ve stayed in. The bed slept well and everything worked. The pool was so clean it sparkled. Nothing even floating in the top. The hotel is located in a busy area, but landscaped and built to allow some privacy We would definitely recommend and certainly will be back."

Reviewed on Sep 21, 2026

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Quality Inn Seneca US-123
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Get rates
Hampton Inn & Suites Seneca-Clemson Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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Tru by Hilton Seneca Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

3 out of 5
800 BYPASS 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (274 reviews)
"Awesome hotel! The staff was so nice and the hotel was so clean. Our room was great! And the breakfast was really good as well."

Reviewed on Sep 15, 2026

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Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (786 reviews)
"The property was certainly not what the pictures portrayed. The location is questionable and we did not feel safe. The room smelt of smoke and we immediately went to front desk. Upon our conversation with the staff we decided it would be best to check out. I messaged Expedia as instructed by the ..."

Reviewed on Sep 22, 2026

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Days Inn by Wyndham Seneca / Clemson Area
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (688 reviews)
"Na"

Reviewed on Sep 14, 2026

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Best Western Seneca-Clemson
See all 1,699 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.