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Seneca

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Seneca Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Fri, Aug 8 - Mon, Aug 11
MCO
Orlando Intl.
GSP
Greenville-Spartanburg Intl.
$120 Roundtrip, found 3 days ago
$120
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Fri, Aug 8 from Orlando Intl. to Greenville-Spartanburg Intl., returning Mon, Aug 11, priced at $120 found 3 days ago
Bargain Flight
Mon, Sep 8 - Sat, Sep 20
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Mon, Sep 8 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Sep 20, priced at $174 found 1 day ago
American Airlines
Wed, Aug 20 - Sun, Aug 24
TPA
Tampa Intl.
GSP
Greenville-Spartanburg Intl.
$187 Roundtrip, found 21 hours ago
$187
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Tampa Intl. to Greenville-Spartanburg Intl., returning Sun, Aug 24, priced at $187 found 21 hours ago
Delta
Tue, Aug 19 - Wed, Aug 27
BWI
Baltimore Washington Intl. Thurgood Marshall
GSP
Greenville-Spartanburg Intl.
$190 Roundtrip, found 1 day ago
$190
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Aug 19 from Baltimore Washington Intl. Thurgood Marshall to Greenville-Spartanburg Intl., returning Wed, Aug 27, priced at $190 found 1 day ago
Delta
Sat, Sep 6 - Tue, Sep 9
PNS
Pensacola Intl.
GSP
Greenville-Spartanburg Intl.
$197 Roundtrip, found 7 hours ago
$197
Roundtrip
found 7 hours ago
Select Delta flight, departing Sat, Sep 6 from Pensacola Intl. to Greenville-Spartanburg Intl., returning Tue, Sep 9, priced at $197 found 7 hours ago
United
Sun, Aug 31 - Sat, Sep 6
ORD
O'Hare Intl.
GSP
Greenville-Spartanburg Intl.
$208 Roundtrip, found 20 hours ago
$208
Roundtrip
found 20 hours ago
Select United flight, departing Sun, Aug 31 from O'Hare Intl. to Greenville-Spartanburg Intl., returning Sat, Sep 6, priced at $208 found 20 hours ago
American Airlines
Fri, Aug 22 - Wed, Aug 27
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 4 days ago
$209
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Aug 22 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, Aug 27, priced at $209 found 4 days ago
United
Sun, Aug 17 - Sun, Aug 24
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
Select United flight, departing Sun, Aug 17 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Sun, Aug 24, priced at $223 found 1 day ago
Bargain Flight
Thu, Sep 4 - Mon, Sep 8
DFW
Dallas-Fort Worth Intl.
GSP
Greenville-Spartanburg Intl.
$235 Roundtrip, found 18 hours ago
$235
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Thu, Sep 4 from Dallas-Fort Worth Intl. to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $235 found 18 hours ago
Delta
Tue, Sep 30 - Tue, Oct 7
MSY
Louis Armstrong New Orleans Intl.
GSP
Greenville-Spartanburg Intl.
$237 Roundtrip, found 1 day ago
$237
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 30 from Louis Armstrong New Orleans Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 7, priced at $237 found 1 day ago
Delta
Mon, Aug 25 - Sat, Aug 30
SYR
Hancock Intl.
GSP
Greenville-Spartanburg Intl.
$240 Roundtrip, found 9 hours ago
$240
Roundtrip
found 9 hours ago
Select Delta flight, departing Mon, Aug 25 from Hancock Intl. to Greenville-Spartanburg Intl., returning Sat, Aug 30, priced at $240 found 9 hours ago
United
Sun, Aug 31 - Sat, Sep 6
FNT
Bishop Intl.
GSP
Greenville-Spartanburg Intl.
$258 Roundtrip, found 4 hours ago
$258
Roundtrip
found 4 hours ago
Select United flight, departing Sun, Aug 31 from Bishop Intl. to Greenville-Spartanburg Intl., returning Sat, Sep 6, priced at $258 found 4 hours ago
Delta
Wed, Nov 19 - Tue, Dec 9
GNV
Gainesville Regional
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Nov 19 from Gainesville Regional to Greenville-Spartanburg Intl., returning Tue, Dec 9, priced at $287 found 1 day ago
Delta
Mon, Oct 27 - Tue, Nov 4
SLC
Salt Lake City Intl.
GSP
Greenville-Spartanburg Intl.
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Oct 27 from Salt Lake City Intl. to Greenville-Spartanburg Intl., returning Tue, Nov 4, priced at $313 found 4 days ago
Delta
Sat, Sep 27 - Tue, Oct 7
BIL
Logan Intl.
GSP
Greenville-Spartanburg Intl.
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Sep 27 from Logan Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 7, priced at $324 found 1 day ago
Delta
Sat, Aug 23 - Tue, Sep 2
GPT
Gulfport - Biloxi Intl.
GSP
Greenville-Spartanburg Intl.
$337 Roundtrip, found 13 hours ago
$337
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, Aug 23 from Gulfport - Biloxi Intl. to Greenville-Spartanburg Intl., returning Tue, Sep 2, priced at $337 found 13 hours ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$120

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (963 reviews)
"Wow if you are in the area and it could be because you’re exhausted with all the driving .. or have an event at Clemson U. Well this is the place to go and unwind! The food, the ambiance, the staff, the room just really will meet your needs! And if not- at least ask! They were very friendly! I want ..."

Reviewed on Jul 28, 2025

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Lakeside Lodge Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (179 reviews)
"From the time they greeted you at the front desk and throughout our stay the staff was very courteous and helpful. The facility was very nice, clean, and welcoming. A very enjoyable stay"

Reviewed on Jul 24, 2025

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Fairfield Inn & Suites Seneca Clemson Univ Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (616 reviews)
Comfortable and convenient
"Easy in and out! Very friendly staff! Breakfast with lots of options and seating. Bed was a bit hard for me but shower was fantastic! Would stay again!"

Reviewed on Jul 27, 2025

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Hampton Inn & Suites Seneca-Clemson Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (743 reviews)
"Great staff and stay."

Reviewed on Jul 24, 2025

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Tru by Hilton Seneca Clemson
Postcard Cabins Lake Hartwell

Postcard Cabins Lake Hartwell

2 out of 5
299 Outpost Rd, Seneca, SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.8/10 Exceptional! (15 reviews)
"Very cute get away"

Reviewed on Jul 29, 2025

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Postcard Cabins Lake Hartwell
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (596 reviews)
"The room was well maintained, quiet and very clean. All amenities I look for were present (refrigerator, microwave, coffee maker, adequate free parking.) Breakfast was varied and bountiful."

Reviewed on Jul 21, 2025

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Best Western Seneca-Clemson
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,022 reviews)
"Great service nice rooms price reasonable"

Reviewed on Jul 28, 2025

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Days Inn by Wyndham Anderson
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
9.6/10 Exceptional! (645 reviews)
"This was a phenomenal place to stay in downtown Clemson. We will definitely be back!"

Reviewed on Jul 29, 2025

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The Shepherd Hotel Downtown Clemson
See all 1,592 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.