Search Cheap Flights to
Seneca

Photo by Cindy Keese

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Seneca Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Bargain Flight
American Airlines
Delta
Delta
United
American Airlines
United
Bargain Flight
Delta
Delta
United
Delta
Delta
Delta
Delta

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$120

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (963 reviews)
"Wow if you are in the area and it could be because you’re exhausted with all the driving .. or have an event at Clemson U. Well this is the place to go and unwind! The food, the ambiance, the staff, the room just really will meet your needs! And if not- at least ask! They were very friendly! I want ..."

Reviewed on Jul 28, 2025

Lakeside Lodge Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (179 reviews)
"From the time they greeted you at the front desk and throughout our stay the staff was very courteous and helpful. The facility was very nice, clean, and welcoming. A very enjoyable stay"

Reviewed on Jul 24, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (616 reviews)
Comfortable and convenient
"Easy in and out! Very friendly staff! Breakfast with lots of options and seating. Bed was a bit hard for me but shower was fantastic! Would stay again!"

Reviewed on Jul 27, 2025

Hampton Inn & Suites Seneca-Clemson Area
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (743 reviews)
"Great staff and stay."

Reviewed on Jul 24, 2025

Tru by Hilton Seneca Clemson
Postcard Cabins Lake Hartwell

Postcard Cabins Lake Hartwell

2 out of 5
299 Outpost Rd, Seneca, SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.8/10 Exceptional! (15 reviews)
"Very cute get away"

Reviewed on Jul 29, 2025

Postcard Cabins Lake Hartwell
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 out of 5
511 Bypass Highway 123, Seneca, SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (596 reviews)
"The room was well maintained, quiet and very clean. All amenities I look for were present (refrigerator, microwave, coffee maker, adequate free parking.) Breakfast was varied and bountiful."

Reviewed on Jul 21, 2025

Best Western Seneca-Clemson
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,022 reviews)
"Great service nice rooms price reasonable"

Reviewed on Jul 28, 2025

Days Inn by Wyndham Anderson
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
9.6/10 Exceptional! (645 reviews)
"This was a phenomenal place to stay in downtown Clemson. We will definitely be back!"

Reviewed on Jul 29, 2025

The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.