Search Cheap Flights to
Seneca

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Seneca Flights as Low as $144

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Fri, May 9 - Mon, May 12
MCO
Orlando Intl.
GSP
Greenville-Spartanburg Intl.
$144 Roundtrip, found 23 hours ago
$144
Roundtrip
found 23 hours ago
Select Breeze Airways flight, departing Fri, May 9 from Orlando Intl. to Greenville-Spartanburg Intl., returning Mon, May 12, priced at $144 found 23 hours ago
Bargain Flight
Tue, Jul 8 - Wed, Jul 9
GRR
Gerald R. Ford Intl.
GSP
Greenville-Spartanburg Intl.
$208 Roundtrip, found 17 hours ago
$208
Roundtrip
found 17 hours ago
Select Bargain Flight flight, departing Tue, Jul 8 from Gerald R. Ford Intl. to Greenville-Spartanburg Intl., returning Wed, Jul 9, priced at $208 found 17 hours ago
United
Thu, Jun 5 - Mon, Jun 9
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$213 Roundtrip, found 19 hours ago
$213
Roundtrip
found 19 hours ago
Select United flight, departing Thu, Jun 5 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Mon, Jun 9, priced at $213 found 19 hours ago
United
Mon, Jun 16 - Tue, Jun 24
ABE
Lehigh Valley Intl.
GSP
Greenville-Spartanburg Intl.
$227 Roundtrip, found 6 days ago
$227
Roundtrip
found 6 days ago
Select United flight, departing Mon, Jun 16 from Lehigh Valley Intl. to Greenville-Spartanburg Intl., returning Tue, Jun 24, priced at $227 found 6 days ago
Bargain Flight
Sat, May 17 - Tue, May 20
BDL
Bradley Intl.
GSP
Greenville-Spartanburg Intl.
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, May 17 from Bradley Intl. to Greenville-Spartanburg Intl., returning Tue, May 20, priced at $229 found 1 day ago
Bargain Flight
Tue, Jun 10 - Wed, Jun 11
STL
Lambert-St. Louis Intl.
GSP
Greenville-Spartanburg Intl.
$232 Roundtrip, found 1 day ago
$232
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jun 10 from Lambert-St. Louis Intl. to Greenville-Spartanburg Intl., returning Wed, Jun 11, priced at $232 found 1 day ago
Bargain Flight
Tue, Jun 24 - Tue, Jul 1
PHL
Philadelphia Intl.
GSP
Greenville-Spartanburg Intl.
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jun 24 from Philadelphia Intl. to Greenville-Spartanburg Intl., returning Tue, Jul 1, priced at $234 found 1 day ago
American Airlines
Fri, May 16 - Sun, May 25
HPN
Westchester County
GSP
Greenville-Spartanburg Intl.
$239 Roundtrip, found 12 hours ago
$239
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Fri, May 16 from Westchester County to Greenville-Spartanburg Intl., returning Sun, May 25, priced at $239 found 12 hours ago
Bargain Flight
Tue, May 27 - Tue, Jun 3
MSY
Louis Armstrong New Orleans Intl.
GSP
Greenville-Spartanburg Intl.
$247 Roundtrip, found 9 hours ago
$247
Roundtrip
found 9 hours ago
Select Bargain Flight flight, departing Tue, May 27 from Louis Armstrong New Orleans Intl. to Greenville-Spartanburg Intl., returning Tue, Jun 3, priced at $247 found 9 hours ago
Delta
Sat, Jun 7 - Mon, Jun 9
CID
Eastern Iowa
GSP
Greenville-Spartanburg Intl.
$253 Roundtrip, found 10 hours ago
$253
Roundtrip
found 10 hours ago
Select Delta flight, departing Sat, Jun 7 from Eastern Iowa to Greenville-Spartanburg Intl., returning Mon, Jun 9, priced at $253 found 10 hours ago
Delta
Wed, Jul 23 - Sun, Jul 27
DEN
Denver Intl.
GSP
Greenville-Spartanburg Intl.
$269 Roundtrip, found 20 hours ago
$269
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jul 23 from Denver Intl. to Greenville-Spartanburg Intl., returning Sun, Jul 27, priced at $269 found 20 hours ago
Bargain Flight
Tue, Jul 15 - Tue, Jul 22
SMF
Sacramento Intl.
GSP
Greenville-Spartanburg Intl.
$277 Roundtrip, found 20 hours ago
$277
Roundtrip
found 20 hours ago
Select Bargain Flight flight, departing Tue, Jul 15 from Sacramento Intl. to Greenville-Spartanburg Intl., returning Tue, Jul 22, priced at $277 found 20 hours ago
Bargain Flight
Sat, May 10 - Wed, May 14
COS
Colorado Springs
GSP
Greenville-Spartanburg Intl.
$278 Roundtrip, found 19 hours ago
$278
Roundtrip
found 19 hours ago
Select Bargain Flight flight, departing Sat, May 10 from Colorado Springs to Greenville-Spartanburg Intl., returning Wed, May 14, priced at $278 found 19 hours ago
Delta
Sat, May 3 - Sat, May 3
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$285 Roundtrip, found 1 day ago
$285
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 3 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, May 3, priced at $285 found 1 day ago
United
Sat, May 3 - Tue, May 6
CYS
Cheyenne Regional
GSP
Greenville-Spartanburg Intl.
$377 Roundtrip, found 6 days ago
$377
Roundtrip
found 6 days ago
Select United flight, departing Sat, May 3 from Cheyenne Regional to Greenville-Spartanburg Intl., returning Tue, May 6, priced at $377 found 6 days ago
Bargain Flight
Fri, May 2 - Mon, May 5
PIT
Pittsburgh Intl.
GSP
Greenville-Spartanburg Intl.
$438 Roundtrip, found 11 hours ago
$438
Roundtrip
found 11 hours ago
Select Bargain Flight flight, departing Fri, May 2 from Pittsburgh Intl. to Greenville-Spartanburg Intl., returning Mon, May 5, priced at $438 found 11 hours ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 8 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $144, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $144 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$144

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
The price is $134 per night from May 2 to May 3
$134
includes taxes & fees
May 2 - May 3
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (856 reviews)
"The hotel was great. It was very clean and the location was perfect for our trip."

Reviewed on Apr 28, 2025

Lakeside Lodge Clemson
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
The price is $101 per night from May 19 to May 20
$101
includes taxes & fees
May 19 - May 20
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (583 reviews)
"Nice place for the price. I would stay here again. Looks newly renovated and was clean. Very comfy bed, pillows. Breakfast was basic but delicious. Staff was excellent. Very pleasant and professional. We enjoyed our short stay."

Reviewed on Apr 27, 2025

Quality Inn Seneca US-123
Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
2 out of 5
299 Outpost Rd, Seneca, SC
The price is $149 per night from May 1 to May 2
$149
includes taxes & fees
May 1 - May 2
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
10/10 Exceptional! (4 reviews)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"

Reviewed on Feb 16, 2025

Postcard Cabins Lake Hartwell
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
The price is $111 per night from May 18 to May 19
$111
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (702 reviews)
"excellent"

Reviewed on Apr 23, 2025

Tru by Hilton Seneca Clemson
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
The price is $102 per night from May 6 to May 7
$102
includes taxes & fees
May 6 - May 7
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (581 reviews)
"Always great service"

Reviewed on Apr 22, 2025

Best Western Seneca-Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
The price is $139 per night from May 4 to May 5
$139
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (590 reviews)
"Mostly liked the location. It is in the part of town where we spent most of our time."

Reviewed on Apr 23, 2025

Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
The price is $142 per night from May 1 to May 2
$142
includes taxes & fees
May 1 - May 2
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (143 reviews)
"Loved that there were choices of restaurants nearby, loved the room and shower and loved that we were given a choice of 1st or 3rd floor.Loved the river view and the river walk."

Reviewed on Apr 28, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
The price is $77 per night from May 25 to May 26
$77
includes taxes & fees
May 25 - May 26
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
"The staff was very polite, helpful and accomadating. Room was very clean. Grounds were manicured."

Reviewed on Apr 19, 2025

Days Inn by Wyndham Seneca / Clemson Area
See all 1,548 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.