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Seneca Flights as Low as $103

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Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $103, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $103 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$103

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,008 reviews)
Spotless room, great staff, and amenities

Reviewed on Jan 25, 2026

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (805 reviews)
The staff here are top tier! We had to be at a meet at the university by 6am and they made breakfast early so our kids could eat before the meet! Genuine care for their guest! Love it here!

Reviewed on Jan 11, 2026

Tru by Hilton Seneca Clemson
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.6/10 Exceptional! (57 reviews)
Very clean! Cozy space. Great 24 hour getaway!

Reviewed on Jan 27, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (675 reviews)
Woman at the front desk

Reviewed on Jan 27, 2026

Hampton Inn & Suites Seneca-Clemson Area
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (673 reviews)
Our stay was very nice. Clean room. The outside was clean.

Reviewed on Jan 20, 2026

Quality Inn Seneca Clemson Area US-123
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 out of 5
800 BYPASS 123 Seneca SC
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (206 reviews)
Spotless, friendly staff, great location.

Reviewed on Jan 14, 2026

Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2 out of 5
11015 N Radio Station Rd Seneca SC
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (724 reviews)
Good

Reviewed on Dec 6, 2025

Days Inn by Wyndham Seneca / Clemson Area
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (753 reviews)
Would definitely stay here again. Was an amazing hotel.

Reviewed on Jan 21, 2026

The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.