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Featured Seneca Hotels with a Pool
Hampton Inn & Suites Seneca-Clemson Area
1011 East North 1st Street, Seneca, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Best Western Seneca-Clemson
511 Bypass Highway 123, Seneca, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn by Wyndham Seneca / Clemson Area
11015 N Radio Station Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Seneca
- Family Hotels in Seneca
- Apartment Hotel in Seneca
- Romantic Hotels in Seneca
- Hotels with Free Parking in Seneca
- Pet-friendly Hotels in Seneca
- Hotels with Hot Tubs in Seneca
- Hotel Wedding Venues in Seneca
- Historic Hotels in Seneca
- Resorts & Hotels with Spas in Seneca
- Hotels with smoking rooms in Seneca
Top Neighborhoods in Seneca
Cities near Seneca
- Highlands Hotels (28.85 mi)
- Clemson Hotels (6.58 mi)
- North Carolina Mountains Hotels (75.4 mi)
- Blue Ridge Mountains Hotels (84.01 mi)
- Brevard Hotels (39.8 mi)
- Cashiers Hotels (30.58 mi)
- Anderson Hotels (21.32 mi)
- Clayton Hotels (28.66 mi)
- Sapphire Hotels (29.23 mi)
- Dillard Hotels (31.47 mi)
- Clarkesville Hotels (32.86 mi)
- Toccoa Hotels (22.8 mi)
- Lake Toxaway Hotels (30.86 mi)
- Easley Hotels (22.2 mi)
- Tiger Hotels (29.4 mi)
- Appalachian Mountains Hotels (501.81 mi)
- Cleveland Hotels (32.87 mi)
- Salem Hotels (14.16 mi)
- Hartwell Hotels (23.01 mi)
- Lavonia Hotels (19.33 mi)
Most Booked Hotels in Seneca
- Quality Inn Seneca Clemson Area US-123
- Days Inn by Wyndham Seneca / Clemson Area
- Hampton Inn & Suites Seneca-Clemson Area
- Best Western Seneca-Clemson
- Tru by Hilton Seneca Clemson
- Days Inn by Wyndham Anderson
- Best Western Plus Clemson Hotel & Conference Center
- Comfort Inn & Suites Clemson - University Area
- Baymont by Wyndham Easley/Greenville
- Microtel Inn & Suites by Wyndham Anderson/Clemson
- Hilton Garden Inn Anderson