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Seneca Vacations

Pack those stellar shades. We have Seneca vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Seneca – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Seneca vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Seneca

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Seneca vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Seneca well.

Top Hotel Deals

See all 122 Hotels in Seneca
Quality Inn Seneca / Clemson

Quality Inn Seneca / Clemson

226 Hi Tech Rd, Seneca
    2.5 out of 5.0
     
     

    Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

    Quality Inn Seneca / Clemson$75

    Quality Inn Seneca / Clemson$75
    Hampton Inn & Suites Seneca-Clemson Area

    Hampton Inn & Suites Seneca-Clemson Area

    1011 East North 1st Street, Seneca
      2.5 out of 5.0
       
       

      Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

      Hampton Inn & Suites Seneca-Clemson Area$116

      Hampton Inn & Suites Seneca-Clemson Area$116
      Days Inn Seneca Clemson SC

      Days Inn Seneca Clemson SC

      11015 N Radio Station Rd, Seneca
        2.0 out of 5.0
         
         

        Situated in Seneca, this motel is within 12 mi (20 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

        Clemson University's James F. Martin Inn

        Clemson University's James F. Martin Inn

        240 Madren Center Drive, Clemson
          3.0 out of 5.0
           
           

          Situated on the waterfront, this hotel is 0.1 mi (0.2 km) from Walker Golf Course and 1.3 mi (2.1 km) from Clemson University. Brooks Center for the Performing ...

          Baymont Inn and Suites Anderson Clemson

          Baymont Inn and Suites Anderson Clemson

          128 Interstate Blvd, Anderson
            2.5 out of 5.0
             
             

            Situated in Anderson, this hotel is 4.1 mi (6.6 km) from Anderson Mall and within 12 mi (20 km) of Anderson County Museum and South Carolina Botanical ...

            Quality Inn

            Quality Inn

            3430 Clemson Blvd, Anderson
              2.0 out of 5.0
               
               

              Situated on the Strip, this hotel is 0.8 mi (1.3 km) from Anderson Mall and within 6 mi (10 km) of Anderson County Museum and Anderson University. NewSpring ...

              Quality Inn$75

              Quality Inn$75
              Microtel Inn & Suites by Wyndham Anderson/Clemson

              Microtel Inn & Suites by Wyndham Anderson/Clemson

              102 Electric City Blvd, Anderson
                2.0 out of 5.0
                 
                 

                Situated in Anderson, this hotel is within 9 mi (15 km) of Anderson Mall, Tri-County Technical College, and NewSpring Church. Anderson County Museum and Anderson ...

                Comfort Suites Anderson

                Comfort Suites Anderson

                118 Interstate Blvd, Anderson
                  2.5 out of 5.0
                   
                   

                  Situated in Anderson, this hotel is within 9 mi (15 km) of Anderson Mall, Anderson County Museum, and Anderson University. Tri-County Technical College and NewSpring ...

                  Comfort Suites Anderson$69

                  Comfort Suites Anderson$69
                  Hilton Garden Inn Anderson

                  Hilton Garden Inn Anderson

                  115 Destination Blvd, Anderson
                    3.0 out of 5.0
                     
                     

                    Situated in the business district, this hotel is within 6 mi (10 km) of Anderson Mall, Anderson County Museum, and Anderson University. NewSpring Church and ...

                    Hilton Garden Inn Anderson$103

                    Hilton Garden Inn Anderson$103
                    Hampton Inn Clemson

                    Hampton Inn Clemson

                    851 Tiger Blvd, Clemson
                      2.5 out of 5.0
                       
                       

                      Located in the heart of Clemson, this hotel is within 3 mi (5 km) of Clemson University, Memorial Stadium, and Little John Coliseum. Brooks Center for the Performing ...

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.