Search for Cheap Deals on
Hotels near Mayo Clinic

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion

Hotels near Mayo Clinic

GuestHouse Inn & Suites Rochester
GuestHouse Inn & Suites Rochester
2.5 out of 5
2.1 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms and the overall value in ...
The Towers At Kahler Grand Hotel
The Towers At Kahler Grand Hotel
4 out of 5
0.1 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
0.2 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the restaurant and the helpful staff ...
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
0.1 km from Mayo Clinic
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the helpful staff and the ...
Marriott Rochester Mayo Clinic
Marriott Rochester Mayo Clinic
3.5 out of 5
0.2 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast, and a free shopping center shuttle. Our guests praise the restaurant ...
Brentwood Inn & Suites
Brentwood Inn & Suites
2.5 out of 5
0.3 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and onsite parking. Our guests praise the helpful staff and the clean rooms ...
Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
3.5 out of 5
0.4 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa hotel in Rochester. Enjoy free WiFi, 2 restaurants, and a full-service spa. Our guests praise the pool and the restaurant in our reviews. ...
Hotel Indigo Rochester – Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area
3.5 out of 5
0.4 km from Mayo Clinic
Fully refundable
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast. Our guests praise the restaurant and the clean ...
TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3 out of 5
0.5 km from Mayo Clinic
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a restaurant. Popular attractions Shops University Square and ...
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
0.5 km from Mayo Clinic
Fully refundable
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Popular attractions Shops University Square ...
Staybridge Suites Rochester - Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area
3 out of 5
1.4 km from Mayo Clinic
Fully refundable
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Popular attractions Soldiers Field Veterans ...
Even Hotel Rochester - Mayo Clinic Area
Even Hotel Rochester - Mayo Clinic Area
3.5 out of 5
1.4 km from Mayo Clinic
Fully refundable
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a restaurant, and breakfast. Popular attractions Soldiers Field Veterans Memorial ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Book a cheap hotel near Mayo Clinic in Downtown Rochester

Booking the perfect hotel sometimes means being near some of the destination’s most attractive amenities—especially if your goal is to keep the entire family entertained. When planning a trip to Downtown Rochester, it pays to book a hotel near convenient shopping. With over 308 hotels near Mayo Clinic, Hotwire helps you find the best place to stay. When you search and book a hotel with Hotwire, you can compare prices, amenities, proximity to Mayo Clinic, and more.

Planning your trip last-minute and don’t mind a little spontaneity? Hotwire is dedicated to getting you top deals on some of the best hotels by Mayo Clinic. Book a Hotwire Hot Rate to save up to 60% off a last-minute Downtown Rochester hotel. You’ll select your desired amenities, general location, dates, price range, and let Hotwire do the rest. Hotwire will choose the hotel that matches your desired preferences, but you won’t know which hotel you have until after you book.

If you plan on staying at a hotel near Mayo Clinic, you’re in for way more than a great shopping experience. Be sure to research the best activities and eateries when planning the itinerary for your visit. Don’t forget to explore other area attractions to maximize your vacation experience. Area restaurants, sightseeing tours, and other draws are certain to beef up your vacation.

Your next adventure awaits, and there’s a cheap hotel near Mayo Clinic—that has all the amenities you’ve come to love—with your name on it.

FAQs about Mayo Clinic hotels:

How to find cheap hotels near Mayo Clinic in Downtown Rochester?

The last thing you want to worry about when booking a trip to Downtown Rochester is overpaying for a quality hotel. When you book with Hotwire, you’re sure to get a great hotel with amazing amenities at a competitive price. Oh, and you’ll also rack up savings you can use for “fun money” for the rest of your vacation.

How many hotels are near Mayo Clinic?

Everyone knows that where you stay while on vacation is just as important as the itinerary. So make sure you don’t get sucked into staying somewhere with lackluster appeal just because it has a great price. Browse 308 hotels in the Mayo Clinic area with Hotwire to find your ideal match.

Are there any pet-friendly hotels near Mayo Clinic?

If you’ve experienced trouble finding suitable pet-friendly hotels for you and your furry friend, worry no more. Hotwire has a large selection of Mayo Clinic area hotels that would love to host you and your beloved pet.

Are there any kid-friendly hotels near Mayo Clinic?

There’s nothing quite like a family vacation. We’re talking about an authentic fun-filled, action-packed, attraction-laden family vacation. And if you’re planning one—Hotwire is your go-to for family-friendly hotel options in Downtown Rochester. Just download the Hotwire app and browse dozens of hotels in the area to find one loaded with desirable fam-friendly amenities.

How to find cheap car rentals near Mayo Clinic?

If you find yourself booking a last-minute trip and are in need of a super cheap car rental deal in Mayo Clinic, book a Hotwire Hot Rate. Save up to 60% off to score one of the best car rental deals in the area.

Is it safe to travel to Downtown Rochester now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Downtown Rochester right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

LEFT_FULLBLEED_ONE_HALF

Prices are always lower in the app!

  • Book and go: Last-minute deals and trip details all in one place
  • Exclusive prices: Hot Rate® Hotels always cost less in the app
  • Fresh features: So slick you’ll never go back to desktop

Text yourself a download link

QR code